Structure of the antitumour enzyme L-methionine gamma-lyase from Pseudomonas putida at 1.8 A resolution
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A novel mechanism of sulfur transfer catalyzed byO-acetylhomoserine sulfhydrylase in the methionine-biosynthetic pathway ofWolinella succinogenesThe role of amino acid residues in the active site of L-methionine γ-lyase from Pseudomonas putidaAlliin is a suicide substrate of Citrobacter freundii methionine γ-lyase: structural bases of inactivation of the enzymeX-Ray snapshots of a pyridoxal enzyme: a catalytic mechanism involving concerted [1,5]-hydrogen sigmatropy in methionine γ-lyaseKinetic characterization of methionine gamma-lyases from the enteric protozoan parasite Entamoeba histolytica against physiological substrates and trifluoromethionine, a promising lead compound against amoebiasis.Methionine gamma-lyase: the unique reaction mechanism, physiological roles, and therapeutic applications against infectious diseases and cancers.Expression, purification and preliminary crystallographic analysis of O-acetylhomoserine sulfhydrylase from Mycobacterium tuberculosis.Current and future perspectives on the chemotherapy of the parasitic protozoa Trichomonas vaginalis and Entamoeba histolytica.Dissociative mechanism for irreversible thermal denaturation of oligomeric proteins.High-Level Expression, Purification and Large-Scale Production of l-Methionine γ-Lyase from Idiomarina as a Novel Anti-Leukemic Drug.Structural and mechanistic insights into homocysteine degradation by a mutant of methionine γ-lyase based on substrate-assisted catalysis.Gene cloning, characterization, and cytotoxic activity of methionine γ-lyase from Clostridium novyi.Pre-steady-state kinetic and structural analysis of interaction of methionine γ-lyase from Citrobacter freundii with inhibitors.L-methionase: a therapeutic enzyme to treat malignancies.The draft genome of tropical fruit durian (Durio zibethinus).Molecular and Spectroscopic Characterization of Aspergillus flavipes and Pseudomonas putida L-Methionine γ-Lyase in Vitro.Targeting altered cancer methionine metabolism with recombinant methioninase (rMETase) overcomes partial gemcitabine-resistance and regresses a patient-derived orthotopic xenograft (PDOX) nude mouse model of pancreatic cancer.Intra-tumor L-methionine level highly correlates with tumor size in both pancreatic cancer and melanoma patient-derived orthotopic xenograft (PDOX) nude-mouse models.Structure of methionine γ-lyase from Clostridium sporogenes.
P2860
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P2860
Structure of the antitumour enzyme L-methionine gamma-lyase from Pseudomonas putida at 1.8 A resolution
description
2007 nî lūn-bûn
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2007 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
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name
Structure of the antitumour en ...... nas putida at 1.8 A resolution
@ast
Structure of the antitumour en ...... nas putida at 1.8 A resolution
@en
Structure of the antitumour en ...... nas putida at 1.8 A resolution
@nl
type
label
Structure of the antitumour en ...... nas putida at 1.8 A resolution
@ast
Structure of the antitumour en ...... nas putida at 1.8 A resolution
@en
Structure of the antitumour en ...... nas putida at 1.8 A resolution
@nl
prefLabel
Structure of the antitumour en ...... nas putida at 1.8 A resolution
@ast
Structure of the antitumour en ...... nas putida at 1.8 A resolution
@en
Structure of the antitumour en ...... nas putida at 1.8 A resolution
@nl
P2093
P356
P1476
Structure of the antitumour en ...... nas putida at 1.8 A resolution
@en
P2093
Akio Takimoto
Daizou Kudou
Kenji Inagaki
Masao Yamashita
Nobuyoshi Esaki
Robert M Hoffman
Shigeo Yagi
Shintaro Misaki
Takashi Tamura
Takayuki Yoshioka
P304
P356
10.1093/JB/MVM055
P577
2007-04-01T00:00:00Z