Crystal Structure of the First Eubacterial Mre11 Nuclease Reveals Novel Features that May Discriminate Substrates During DNA Repair
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Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repairDNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease ActivitiesStructural basis for DNA recognition and nuclease processing by the Mre11 homologue SbcD in double-strand breaks repairEnvisioning the dynamics and flexibility of Mre11-Rad50-Nbs1 complex to decipher its roles in DNA replication and repairAutoinhibition of bacteriophage T4 Mre11 by its C-terminal domain.Crystal structure of the Mre11-Rad50-ATPγS complex: understanding the interplay between Mre11 and Rad50Structure and computational analysis of a novel protein with metallopeptidase-like and circularly permuted winged-helix-turn-helix domains reveals a possible role in modified polysaccharide biosynthesisMimivirus reveals Mre11/Rad50 fusion proteins with a sporadic distribution in eukaryotes, bacteria, viruses and plasmidsMre11-Rad50 complex crystals suggest molecular calisthenics.Functional Analysis of the Bacteriophage T4 Rad50 Homolog (gp46) Coiled-coil DomainDisruption of the bacteriophage T4 Mre11 dimer interface reveals a two-state mechanism for exonuclease activityMRE11 facilitates the removal of human topoisomerase II complexes from genomic DNA.Disease-associated MRE11 mutants impact ATM/ATR DNA damage signaling by distinct mechanisms.Archaeal genome guardians give insights into eukaryotic DNA replication and damage response proteins.Structural studies of DNA end detection and resection in homologous recombination.ATP puts the brake on DNA double-strand break repair: a new study shows that ATP switches the Mre11-Rad50-Nbs1 repair factor between signaling and processing of DNA ends.A network of allosterically coupled residues in the bacteriophage T4 Mre11-Rad50 complexStructure of the catalytic domain of Mre11 from Chaetomium thermophilum.Contribution of Pentose Catabolism to Molecular Hydrogen Formation by Targeted Disruption of Arabinose Isomerase (araA) in the Hyperthermophilic Bacterium Thermotoga maritima.Post-translational methylations of the archaeal Mre11:Rad50 complex throughout the DNA damage response.The MRE11-RAD50-NBS1 Complex Conducts the Orchestration of Damage Signaling and Outcomes to Stress in DNA Replication and Repair.
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P2860
Crystal Structure of the First Eubacterial Mre11 Nuclease Reveals Novel Features that May Discriminate Substrates During DNA Repair
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2010 nî lūn-bûn
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2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2010 թվականի ապրիլին հրատարակված գիտական հոդված
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2010年の論文
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年學術文章
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Crystal Structure of the First ...... e Substrates During DNA Repair
@ast
Crystal Structure of the First ...... e Substrates During DNA Repair
@en
Crystal Structure of the First ...... e Substrates During DNA Repair
@nl
type
label
Crystal Structure of the First ...... e Substrates During DNA Repair
@ast
Crystal Structure of the First ...... e Substrates During DNA Repair
@en
Crystal Structure of the First ...... e Substrates During DNA Repair
@nl
prefLabel
Crystal Structure of the First ...... e Substrates During DNA Repair
@ast
Crystal Structure of the First ...... e Substrates During DNA Repair
@en
Crystal Structure of the First ...... e Substrates During DNA Repair
@nl
P2093
P2860
P50
P1476
Crystal Structure of the First ...... e Substrates During DNA Repair
@en
P2093
Andrew T Morse
Ashley M Deacon
Christine B Trame
Christopher L Rife
Davide Moiani
Debanu Das
Dustin Ernst
Gye Won Han
Henry J Tien
Hsiu-Ju Chiu
P2860
P304
P356
10.1016/J.JMB.2010.01.049
P407
P50
P577
2010-04-02T00:00:00Z