The novel 2Fe–2S outer mitochondrial protein mitoNEET displays conformational flexibility in its N-terminal cytoplasmic tethering domain
about
Mutation of the His ligand in mitoNEET stabilizes the 2Fe–2S cluster despite conformational heterogeneity in the ligand environmentMitoneet mediates TNFα-induced necroptosis promoted by exposure to fructose and ethanol.Binding of histidine in the (Cys)3(His)1-coordinated [2Fe-2S] cluster of human mitoNEET.The mitochondrial complex I activity is reduced in cells with impaired cystic fibrosis transmembrane conductance regulator (CFTR) function.Facile transfer of [2Fe-2S] clusters from the diabetes drug target mitoNEET to an apo-acceptor proteinNovel ligands that target the mitochondrial membrane protein mitoNEETMitoNEET-dependent formation of intermitochondrial junctions.Characterization of Arabidopsis NEET reveals an ancient role for NEET proteins in iron metabolism.The unique fold and lability of the [2Fe-2S] clusters of NEET proteins mediate their key functions in health and disease.
P2860
Q27668146-212BEB7F-E769-484A-B77B-1FE76A929906Q30571859-0E73768A-6A0C-45BA-8DE3-504DABA90166Q33645749-CAD4C196-7285-455A-B017-19E97569E29AQ34489613-336D6B7B-D9B5-415D-B323-F7F1C8083D43Q35164588-7C811EAB-B651-43EB-9D0D-D0AE8A117E57Q36337739-3DBD155E-9F18-4BF3-92B2-FD25C45FB669Q41293358-2E966D55-57D6-4F13-BE1F-B86668AB9359Q47205694-FE921CA5-08E3-4B66-8787-26CF66D0A998Q50051515-59E52A74-80B5-4B25-B66C-CEF2C6DFA8D7
P2860
The novel 2Fe–2S outer mitochondrial protein mitoNEET displays conformational flexibility in its N-terminal cytoplasmic tethering domain
description
2009 nî lūn-bûn
@nan
2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
The novel 2Fe–2S outer mitocho ...... l cytoplasmic tethering domain
@ast
The novel 2Fe–2S outer mitocho ...... l cytoplasmic tethering domain
@en
The novel 2Fe–2S outer mitocho ...... l cytoplasmic tethering domain
@nl
type
label
The novel 2Fe–2S outer mitocho ...... l cytoplasmic tethering domain
@ast
The novel 2Fe–2S outer mitocho ...... l cytoplasmic tethering domain
@en
The novel 2Fe–2S outer mitocho ...... l cytoplasmic tethering domain
@nl
prefLabel
The novel 2Fe–2S outer mitocho ...... l cytoplasmic tethering domain
@ast
The novel 2Fe–2S outer mitocho ...... l cytoplasmic tethering domain
@en
The novel 2Fe–2S outer mitocho ...... l cytoplasmic tethering domain
@nl
P2093
P2860
P50
P921
P1476
The novel 2Fe–2S outer mitocho ...... l cytoplasmic tethering domain
@en
P2093
Andrea R Conlan
Edward C Abresch
Mark L Paddock
Melinda Roy
Patricia A Jennings
Sandra Wiley
P2860
P356
10.1107/S1744309109019605
P577
2009-07-01T00:00:00Z