Application of crystallographic and modeling methods in the design of purine nucleoside phosphorylase inhibitors
about
Role of purine nucleoside phosphorylase in interactions between 2',3'-dideoxyinosine and allopurinol, ganciclovir, or tenofovirImmucillin H, a powerful transition-state analog inhibitor of purine nucleoside phosphorylase, selectively inhibits human T lymphocytesConservation of structure and activity in Plasmodium purine nucleoside phosphorylasesStructure of grouper iridovirus purine nucleoside phosphorylaseApplication of the PM6 semi-empirical method to modeling proteins enhances docking accuracy of AutoDockStructural analyses reveal two distinct families of nucleoside phosphorylasesCrystal Structure of Schistosoma mansoni Adenosine Phosphorylase/5'-Methylthioadenosine Phosphorylase and Its Importance on Adenosine Salvage PathwayXanthosine and xanthineBenchmarking sets for molecular dockingThree-dimensional models of non-NMDA glutamate receptorsDecoys for dockingLoop-tryptophan human purine nucleoside phosphorylase reveals submillisecond protein dynamics.Natural Products as New Treatment Options for Trichomoniasis: A Molecular Docking Investigation.Transition Path Sampling Study of the Reaction Catalyzed by Purine Nucleoside PhosphorylaseAnalysis of cyclic and acyclic nicotinic cholinergic agonists using radioligand binding, single channel recording, and nuclear magnetic resonance spectroscopy.Conformational dynamics in human purine nucleoside phosphorylase with reactants and transition-state analoguesRemote mutations and active site dynamics correlate with catalytic properties of purine nucleoside phosphorylase.Modulating Enzyme Catalysis through Mutations Designed to Alter Rapid Protein Dynamics.Multisubstrate adduct inhibitors: drug design and biological tools.8-Azapurines as isosteric purine fluorescent probes for nucleic acid and enzymatic research.Application of X-ray crystallographic methods in the design of purine nucleoside phosphorylase inhibitors.Activities of two 9-deazaguanine analogue inhibitors of purine nucleoside phosphorylase, CI-972 and PD 141955, in vitro and in vivo.Design of an adenosine phosphorylase by active-site modification of murine purine nucleoside phosphorylase. Enzyme kinetics and molecular dynamics simulation of Asn-243 and Lys-244 substitutions of purine nucleoside phosphorylase.The Role of Motivation in Scientific Research III: The Paths of ProgressInterdisciplinary approaches to drug discovery An academic approach
P2860
Q24321512-999EF4EB-9E87-4F3A-8935-9A8A8AD584DFQ24635226-23D9CF88-B1A6-498D-AA25-F4D78C5473DFQ27646441-1DA0026E-8062-455E-B872-382D02FEF3C4Q27659406-7B83C5D3-4A1C-4910-8155-980083EAAD08Q27702054-9F16B58F-6A41-40C9-83E5-625ACE9F61F2Q28366428-07BA5C4B-F51C-4281-B746-AB9D153909A0Q28554851-5270981C-94D3-4591-9C14-11719B481FDAQ29398416-544C50FC-1286-403D-9FD5-79C694425AA2Q29619637-E4F70988-5169-4F5F-904B-F44AB5BFDD8BQ30177008-30B9E668-77C8-4FEF-AC36-1CB9DF61DC05Q30350781-5365BDE9-53D6-461B-8DBF-B42B276C1C81Q33405379-6F6F866C-4AFC-45B7-8F54-564AFC6B63ABQ33553302-CF18707D-285D-4A7E-85C3-97D6617D0421Q34018484-D5ED664E-0EA4-460E-BC9C-7CBCE7AEDEFFQ34092074-9554DD2E-3526-4568-8D54-127C2DD60799Q34424004-91BC7CFC-0031-45C1-8F59-E9D5DB0A8C4DQ36632125-69C4019F-4DD1-4378-9A45-E928C760ECEBQ36693213-943713FE-7220-4711-97B4-B15B4AAE04A8Q37632419-47143486-6BEF-4F3D-B91A-2050ACC27271Q38240046-9D0E45E0-BBD5-4CD0-B295-2B1D53F1D21FQ40841450-F5291F43-090B-4CB0-ABA3-011420006B55Q42288411-C7E61040-DA9C-451D-9CEF-2D0E3DC9F59BQ42995267-DB623D51-50FF-4C5A-AC2F-78922C99497AQ58533123-6D1E157A-7FC7-4340-9FCC-A6E632A9C287Q58540750-D422A0FA-7F7E-4608-8605-A411DCEDA07B
P2860
Application of crystallographic and modeling methods in the design of purine nucleoside phosphorylase inhibitors
description
1991 nî lūn-bûn
@nan
1991 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
Application of crystallographi ...... oside phosphorylase inhibitors
@ast
Application of crystallographi ...... oside phosphorylase inhibitors
@en
Application of crystallographi ...... oside phosphorylase inhibitors
@nl
type
label
Application of crystallographi ...... oside phosphorylase inhibitors
@ast
Application of crystallographi ...... oside phosphorylase inhibitors
@en
Application of crystallographi ...... oside phosphorylase inhibitors
@nl
prefLabel
Application of crystallographi ...... oside phosphorylase inhibitors
@ast
Application of crystallographi ...... oside phosphorylase inhibitors
@en
Application of crystallographi ...... oside phosphorylase inhibitors
@nl
P2093
P2860
P356
P1476
Application of crystallographi ...... oside phosphorylase inhibitors
@en
P2093
J A Montgomery
J A Secrist
S E Ealick
P2860
P304
P356
10.1073/PNAS.88.24.11540
P407
P577
1991-12-15T00:00:00Z