Structural insight into distinct mechanisms of protease inhibition by antibodies
about
Structure of an Fab–Protease Complex Reveals a Highly Specific Non-canonical Mechanism of InhibitionStructural and Functional Analysis of a C3b-specific Antibody That Selectively Inhibits the Alternative Pathway of ComplementA Single-Domain Llama Antibody Potently Inhibits the Enzymatic Activity of Botulinum Neurotoxin by Binding to the Non-Catalytic α-Exosite Binding RegionHedgehog Pathway Antagonist 5E1 Binds Hedgehog at the Pseudo-active SiteAllosteric antibody inhibition of human hepsin proteaseA Reverse Binding Motif That Contributes to Specific Protease Inhibition by AntibodiesInhibiting Alternative Pathway Complement Activation by Targeting the Factor D ExositeAllosteric Inhibition of the NS2B-NS3 Protease from Dengue VirusSelection of full-length IgGs by tandem display on filamentous phage particles and Escherichia coli fluorescence-activated cell sorting screening.Interactions outside the proteinase-binding loop contribute significantly to the inhibition of activated coagulation factor XII by its canonical inhibitor from corn.An allosteric anti-hepsin antibody derived from a constrained phage display library.Inhibition and Reversal of Microbial Attachment by an Antibody with Parasteric Activity against the FimH Adhesin of Uropathogenic E. coliMonoclonal Antibodies Targeting the Alpha-Exosite of Botulinum Neurotoxin Serotype/A Inhibit Catalytic ActivityNew Infestin-4 Mutants with Increased Selectivity against Factor XIIa.Active-site MMP-selective antibody inhibitors discovered from convex paratope synthetic libraries.Generation of inhibitory monoclonal antibodies targeting matrix metalloproteinase-14 by motif grafting and CDR optimization.An inhibitory antibody against dipeptidyl peptidase IV improves glucose tolerance in vivoA Camelid-derived Antibody Fragment Targeting the Active Site of a Serine Protease Balances between Inhibitor and Substrate Behavior.The structure of a furin-antibody complex explains non-competitive inhibition by steric exclusion of substrate conformers.Hepatocyte growth factor activator (HGFA): molecular structure and interactions with HGFA inhibitor-1 (HAI-1).Structural and mechanistic insight into how antibodies inhibit serine proteases.Mechanisms of macromolecular protease inhibitorsα-Ketobenzothiazole Serine Protease Inhibitors of Aberrant HGF/c-MET and MSP/RON Kinase Pathway Signaling in Cancer.Engineering a potent inhibitor of matriptase from the natural hepatocyte growth factor activator inhibitor type-1 (HAI-1) protein.Selectivity Conversion of Protease Inhibitory Antibodies
P2860
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P2860
Structural insight into distinct mechanisms of protease inhibition by antibodies
description
2007 nî lūn-bûn
@nan
2007 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Structural insight into distinct mechanisms of protease inhibition by antibodies
@ast
Structural insight into distinct mechanisms of protease inhibition by antibodies
@en
Structural insight into distinct mechanisms of protease inhibition by antibodies
@nl
type
label
Structural insight into distinct mechanisms of protease inhibition by antibodies
@ast
Structural insight into distinct mechanisms of protease inhibition by antibodies
@en
Structural insight into distinct mechanisms of protease inhibition by antibodies
@nl
prefLabel
Structural insight into distinct mechanisms of protease inhibition by antibodies
@ast
Structural insight into distinct mechanisms of protease inhibition by antibodies
@en
Structural insight into distinct mechanisms of protease inhibition by antibodies
@nl
P2093
P2860
P3181
P356
P1476
Structural insight into distinct mechanisms of protease inhibition by antibodies
@en
P2093
Daniel Kirchhofer
Michael T Lipari
Rajkumar Ganesan
Scott Stawicki
Steven Shia
Wei-Ching Liang
P2860
P304
P3181
P356
10.1073/PNAS.0708251104
P407
P577
2007-12-11T00:00:00Z