Structure analysis of bone morphogenetic protein-2 type I receptor complexes reveals a mechanism of receptor inactivation in juvenile polyposis syndrome
about
New insights into the molecular mechanism of multiple synostoses syndrome (SYNS): mutation within the GDF5 knuckle epitope causes noggin-resistanceA Selection Fit Mechanism in BMP Receptor IA as a Possible Source for BMP Ligand-Receptor PromiscuityAn evolutionary and structural characterization of mammalian protein complex organization.Modifications of human growth differentiation factor 9 to improve the generation of embryos from low competence oocytes.Optimal effector functions in human natural killer cells rely upon autocrine bone morphogenetic protein signalingSecreted phosphoprotein 24 kD (Spp24) and Spp14 affect TGF-β induced bone formation differentlyGDF-5 can act as a context-dependent BMP-2 antagonist.A host-guest relationship in bone morphogenetic protein receptor-II defines specificity in ligand-receptor recognition.Discovery of fully human anti-MET monoclonal antibodies with antitumor activity against colon cancer tumor models in vivo.Duplications involving a conserved regulatory element downstream of BMP2 are associated with brachydactyly type A2.Receptor oligomerization and beyond: a case study in bone morphogenetic proteins.Enrichment map profiling of the cancer invasion front suggests regulation of colorectal cancer progression by the bone morphogenetic protein antagonist, gremlin-1.Production, Isolation, and Structural Analysis of Ligands and Receptors of the TGF-β Superfamily.Signaling Receptors for TGF-β Family Members.Structural Biology and Evolution of the TGF-β FamilyN-linked glycosylation of the bone morphogenetic protein receptor type 2 (BMPR2) enhances ligand binding.SKEMPI: a Structural Kinetic and Energetic database of Mutant Protein Interactions and its use in empirical models.Expression patterns of bone morphogenetic protein antagonists in colorectal cancer desmoplastic invasion fronts.BMPR1A mutations in juvenile polyposis affect cellular localization.Crystallization of BMP receptor type IA bound to the antibody Fab fragment AbD1556.The anti-myeloma activity of bone morphogenetic protein 2 predominantly relies on the induction of growth arrest and is apoptosis-independent.BMP-2 and bFGF release and in vitro effect on human osteoblasts after adsorption to bone grafts and biomaterials.BmpR1A is a major type 1 BMP receptor for BMP-Smad signaling during skull development.BMP pathway suppression is an early event in inflammation-driven colon neoplasmatogenesis of uPA-deficient mice.
P2860
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P2860
Structure analysis of bone morphogenetic protein-2 type I receptor complexes reveals a mechanism of receptor inactivation in juvenile polyposis syndrome
description
2008 nî lūn-bûn
@nan
2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Structure analysis of bone mor ...... in juvenile polyposis syndrome
@ast
Structure analysis of bone mor ...... in juvenile polyposis syndrome
@en
Structure analysis of bone mor ...... in juvenile polyposis syndrome
@nl
type
label
Structure analysis of bone mor ...... in juvenile polyposis syndrome
@ast
Structure analysis of bone mor ...... in juvenile polyposis syndrome
@en
Structure analysis of bone mor ...... in juvenile polyposis syndrome
@nl
prefLabel
Structure analysis of bone mor ...... in juvenile polyposis syndrome
@ast
Structure analysis of bone mor ...... in juvenile polyposis syndrome
@en
Structure analysis of bone mor ...... in juvenile polyposis syndrome
@nl
P2093
P2860
P50
P356
P1476
Structure analysis of bone mor ...... in juvenile polyposis syndrome
@en
P2093
Axel Seher
Kai Heinecke
Laura van Geersdaele
Thomas D Mueller
P2860
P304
P356
10.1074/JBC.M706029200
P407
P577
2008-02-29T00:00:00Z