2-amino-1,3-thiazol-4(5H)-ones as potent and selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitors: enzyme-ligand co-crystal structure and demonstration of pharmacodynamic effects in C57Bl/6 mice

2-amino-1,3-thiazol-4(5H)-ones as potent and selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitors: enzyme-ligand co-crystal structure and demonstration of pharmacodynamic effects in C57Bl/6 mice

Item
http://www.wikidata.org/entity/Q27650349
Optimization of 1,2,4-Triazolopyridines as Inhibitors of Human 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD-1)11β-Hydroxysteroid dehydrogenase type 1: relevance of its modulation in the pathophysiology of obesity, the metabolic syndrome and type 2 diabetes mellitus.The lipophilic bullet hits the targets: medicinal chemistry of adamantane derivativesHuman hydroxysteroid dehydrogenases and pre-receptor regulation: insights into inhibitor design and evaluation.Crystal structures of 11β-hydroxysteroid dehydrogenase type 1 and their use in drug discovery.Peripheral targets in obesity treatment: a comprehensive update.On-column ligand exchange for structure-based drug design: a case study with human 11β-hydroxysteroid dehydrogenase type 1.2-Allylaminothiazole and 2-allylaminodihydrothiazole derivatives: synthesis, characterization, and evaluation of bioactivity.
P2860

2-amino-1,3-thiazol-4(5H)-ones as potent and selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitors: enzyme-ligand co-crystal structure and demonstration of pharmacodynamic effects in C57Bl/6 mice

Item
http://www.wikidata.org/entity/Q27650349
description
2008 nî lūn-bûn
@nan
2008 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2008年の論文
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2008年論文
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2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
2-amino-1,3-thiazol-4(5H)-ones ...... ynamic effects in C57Bl/6 mice
@ast
2-amino-1,3-thiazol-4(5H)-ones ...... ynamic effects in C57Bl/6 mice
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2-amino-1,3-thiazol-4(5H)-ones ...... ynamic effects in C57Bl/6 mice
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type
label
2-amino-1,3-thiazol-4(5H)-ones ...... ynamic effects in C57Bl/6 mice
@ast
2-amino-1,3-thiazol-4(5H)-ones ...... ynamic effects in C57Bl/6 mice
@en
2-amino-1,3-thiazol-4(5H)-ones ...... ynamic effects in C57Bl/6 mice
@nl
prefLabel
2-amino-1,3-thiazol-4(5H)-ones ...... ynamic effects in C57Bl/6 mice
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2-amino-1,3-thiazol-4(5H)-ones ...... ynamic effects in C57Bl/6 mice
@en
2-amino-1,3-thiazol-4(5H)-ones ...... ynamic effects in C57Bl/6 mice
@nl
P1433
P1476
P2093
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P478
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P698
P921
P356
P1433
P1476
2-amino-1,3-thiazol-4(5H)-ones ...... ynamic effects in C57Bl/6 mice
@en
P2093
P304
P31
P356
P407
P433
P478
P577
P698
P921