Crystal structure of unphosphorylated STAT3 core fragment
about
The Complex Role of STAT3 in Viral InfectionsThe consequences of selective inhibition of signal transducer and activator of transcription 3 (STAT3) tyrosine705 phosphorylation by phosphopeptide mimetic prodrugs targeting the Src homology 2 (SH2) domainObservation of unphosphorylated STAT3 core protein binding to target dsDNA by PEMSA and X-ray crystallographyHow Intrinsic Molecular Dynamics Control Intramolecular Communication in Signal Transducers and Activators of Transcription Factor STAT5Inhibitory effect of ent-Sauchinone on amyloidogenesis via inhibition of STAT3-mediated NF-κB activation in cultured astrocytes and microglial BV-2 cellsDynamics of the STAT3 transcription factor: nuclear import dependent on Ran and importin-β1.Changes in signal transducer and activator of transcription 3 (STAT3) dynamics induced by complexation with pharmacological inhibitors of Src homology 2 (SH2) domain dimerization.Anti-arthritis effects of (E)-2,4-bis(p-hydroxyphenyl)-2-butenal are mediated by inhibition of the STAT3 pathwayPotent and selective phosphopeptide mimetic prodrugs targeted to the Src homology 2 (SH2) domain of signal transducer and activator of transcription 3.Impact of the N-Terminal Domain of STAT3 in STAT3-Dependent Transcriptional ActivityAllosteric Communication across STAT3 Domains Associated with STAT3 Function and Disease-Causing Mutation.Rhodium(II) Proximity-Labeling Identifies a Novel Target Site on STAT3 for Inhibitors with Potent Anti-Leukemia Activity.Structural basis for DNA recognition by STAT6.EGFR signaling and autophagy dependence for growth, survival, and therapy resistance.Novel inhibitors of signal transducer and activator of transcription 3 signaling pathway: an update on the recent patent literature.STAT3 the oncogene - still eluding therapy?A fluorescent reporter of the phosphorylation status of the substrate protein STAT3.Role of STAT3 in Genesis and Progression of Human Malignant Gliomas.Evaluation of quantitative assays for the identification of direct signal transducer and activator of transcription 3 (STAT3) inhibitors.The replication and transcription activator of murine gammaherpesvirus 68 cooperatively enhances cytokine-activated, STAT3-mediated gene expression.Distinct mutations at the same positions of STAT3 cause either loss or gain of function.An SH2 domain model of STAT5 in complex with phospho-peptides define "STAT5 Binding Signatures".Structural characterization of unphosphorylated STAT5a oligomerization equilibrium in solution by small-angle X-ray scattering.Nanomolar-Potency Small Molecule Inhibitor of STAT5 Protein.Characterization of molecular recognition of STAT3 SH2 domain inhibitors through molecular simulation.AlloFinder: a strategy for allosteric modulator discovery and allosterome analyses.Structural Biology of STAT3 and Its Implications for Anticancer Therapies Development.
P2860
Q26801053-A98C2AFD-F90F-46AC-B69E-9C87FAF9599AQ26861758-C5AEB603-EDB5-40EB-A6F9-CE4036B346A6Q27684066-4B968070-6067-4F7E-965C-C3D6060E1308Q28551904-6386A289-394B-4ABB-B1DD-B595D144318FQ33877126-8CB6B69B-377C-449C-9124-E0C91ECB4703Q33916478-FF1589CD-31B0-41D1-BAB3-895D5C55DEA5Q34552575-4EBD06F7-017F-4D33-BC00-083335970FC0Q34570822-65FBB7F6-B3E2-4918-917E-D54FF1C04D11Q35869426-4A19FA4A-D498-4E57-8489-A7DF12706795Q36033384-B655BDE5-E49A-46C6-8BD7-F656D20DED82Q36619740-F57563E3-961A-446E-AF75-18D0BC00B420Q37295115-45079CE5-DA11-42B4-801F-B99CC7102871Q37469583-F14D2A4E-A6F8-488A-9A70-ACC3246623C8Q38171032-F2E024FF-7ED4-4958-A49B-745D14A1CC26Q38179031-AAB7FB7B-D3D1-47CD-A0AE-77A50911BC1CQ38396909-D80CF68A-BC7F-4276-B028-72C2B9B18E23Q38769839-982D0AEC-D3C4-4805-99F3-335DDA890041Q38962315-7597167A-0492-4E52-A381-4F562521BCC3Q39237865-BA99B49C-56A6-40CF-9224-A234E9F00B07Q40077951-305FFB25-0F42-4392-9EA9-3705B35A6442Q40636507-74D795C4-C05C-494A-9D76-3165D6D4C5FFQ41264901-06E54A72-7085-469F-8DF5-2B464A55C0D1Q41904480-F61C680E-16D8-4881-873E-DFBE210B3916Q43009401-2DF26761-AC92-46C9-BC5E-F60374E24FA0Q53436083-3E73CC0D-E5E1-4DCD-BBD8-9E163E5AB28FQ55518791-E77E8840-9CA2-46B4-9856-6C14080AF93AQ55637644-DC7DA43E-B4D7-4B5C-964A-545A77AE3A7F
P2860
Crystal structure of unphosphorylated STAT3 core fragment
description
2008 nî lūn-bûn
@nan
2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Crystal structure of unphosphorylated STAT3 core fragment
@ast
Crystal structure of unphosphorylated STAT3 core fragment
@en
Crystal structure of unphosphorylated STAT3 core fragment
@nl
type
label
Crystal structure of unphosphorylated STAT3 core fragment
@ast
Crystal structure of unphosphorylated STAT3 core fragment
@en
Crystal structure of unphosphorylated STAT3 core fragment
@nl
prefLabel
Crystal structure of unphosphorylated STAT3 core fragment
@ast
Crystal structure of unphosphorylated STAT3 core fragment
@en
Crystal structure of unphosphorylated STAT3 core fragment
@nl
P2093
P1476
Crystal structure of unphosphorylated STAT3 core fragment
@en
P2093
Claudia Mertens
John S McMurray
Michael J Romanowski
Pijus K Mandal
Ravi Krishnaraj
Xiaomin Chen
Zhiyong Ren
P356
10.1016/J.BBRC.2008.04.049
P407
P577
2008-09-12T00:00:00Z