Structural insight into signal conversion and inactivation by NTPDase2 in purinergic signaling
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Structural insight into activation mechanism of Toxoplasma gondii nucleoside triphosphate diphosphohydrolases by disulfide reductionThe crystal structure of Toxoplasma gondii nucleoside triphosphate diphosphohydrolase 1 represents a conformational intermediate in the reductive activation mechanism of the tetrameric enzymeThe ATP/ADP substrate specificity switch between Toxoplasma gondii NTPDase1 and NTPDase3 is caused by an altered mode of binding of the substrate baseStructures of Legionella pneumophila NTPDase1 in complex with polyoxometallatesThe biochemical properties of the Arabidopsis ecto-nucleoside triphosphate diphosphohydrolase AtAPY1 contradict a direct role in purinergic signalingCharacterization of a monoclonal antibody as the first specific inhibitor of human NTP diphosphohydrolase-3 : partial characterization of the inhibitory epitope and potential applicationsRevelation of a catalytic calcium-binding site elucidates unusual metal dependence of a human apyraseCellular function and molecular structure of ecto-nucleotidases.Epitope mapping in cell surface proteins by site-directed masking: defining the structural elements of NTPDase3 inhibition by a monoclonal antibody.Proline residues link the active site to transmembrane domain movements in human nucleoside triphosphate diphosphohydrolase 3 (NTPDase3)The GDA1_CD39 superfamily: NTPDases with diverse functions.Possible effects of microbial ecto-nucleoside triphosphate diphosphohydrolases on host-pathogen interactions.Autocrine ATP release coupled to extracellular pyrophosphate accumulation in vascular smooth muscle cells.The ENTPD5/mt-PCPH oncoprotein is a catalytically inactive member of the ectonucleoside triphosphate diphosphohydrolase family.Therapeutic potentials of ecto-nucleoside triphosphate diphosphohydrolase, ecto-nucleotide pyrophosphatase/phosphodiesterase, ecto-5'-nucleotidase, and alkaline phosphatase inhibitors.Structures and kinetics for plant nucleoside triphosphate diphosphohydrolases support a domain motion catalytic mechanism.Multiple ecto-nucleoside triphosphate diphosphohydrolases facilitate intracellular replication of Legionella pneumophila.New crystal forms of NTPDase1 from the bacterium Legionella pneumophilaCD39 reveals novel insights into the role of transmembrane domains in protein processing, apical targeting and activity.Mycobacterium tuberculosis proteasomal ATPase Mpa has a β-grasp domain that hinders docking with the proteasome core protease.Mutagenesis of apyrase conserved region 1 alters the nucleotide substrate specificity.Extracellular purine metabolism in blood vessels (Part II): Activity of ecto-enzymes in blood vessels of patients with abdominal aortic aneurysm.Conserved polar residues stabilize transmembrane domains and promote oligomerization in human nucleoside triphosphate diphosphohydrolase 3Apyrase (nucleoside triphosphate-diphosphohydrolase) and extracellular nucleotides regulate cotton fiber elongation in cultured ovules.Various N-glycoforms differentially upregulate E-NTPDase activity of the NTPDase3/CD39L3 ecto-enzymatic domain.Molecular dynamic simulations reveal structural insights into substrate and inhibitor binding modes and functionality of Ecto-Nucleoside Triphosphate Diphosphohydrolases.Ectonucleotidase inhibitors: a patent review (2011-2016).
P2860
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P2860
Structural insight into signal conversion and inactivation by NTPDase2 in purinergic signaling
description
2008 nî lūn-bûn
@nan
2008 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Structural insight into signal ...... PDase2 in purinergic signaling
@ast
Structural insight into signal ...... PDase2 in purinergic signaling
@en
Structural insight into signal ...... PDase2 in purinergic signaling
@nl
type
label
Structural insight into signal ...... PDase2 in purinergic signaling
@ast
Structural insight into signal ...... PDase2 in purinergic signaling
@en
Structural insight into signal ...... PDase2 in purinergic signaling
@nl
prefLabel
Structural insight into signal ...... PDase2 in purinergic signaling
@ast
Structural insight into signal ...... PDase2 in purinergic signaling
@en
Structural insight into signal ...... PDase2 in purinergic signaling
@nl
P2860
P356
P1476
Structural insight into signal ...... PDase2 in purinergic signaling
@en
P2860
P304
P356
10.1073/PNAS.0802535105
P407
P577
2008-05-13T00:00:00Z