Cysteine p K a Depression by a Protonated Glutamic Acid in Human DJ-1 † ‡
about
DJ-1 is a copper chaperone acting on SOD1 activationStructure and Function of Parkin, PINK1, and DJ-1, the Three Musketeers of NeuroprotectionCysteine oxidative posttranslational modifications: emerging regulation in the cardiovascular systemThe redox biochemistry of protein sulfenylation and sulfinylationFormation of a Stabilized Cysteine Sulfinic Acid Is Critical for the Mitochondrial Function of the Parkinsonism Protein DJ-1Evolution of New Enzymatic Function by Structural Modulation of Cysteine Reactivity in Pseudomonas fluorescens Isocyanide Hydratasep K a Coupling at the Intein Active Site: Implications for the Coordination Mechanism of Protein Splicing with a Conserved AspartateChemical genetic strategy for targeting protein kinases based on covalent complementarityInfluence of peptide dipoles and hydrogen bonds on reactive cysteine pKavalues in fission yeast DJ-1Identification of an artificial peptide motif that binds and stabilizes reduced human DJ-1Conservation of oxidative protein stabilization in an insect homologue of parkinsonism-associated protein DJ-1Tuning of thioredoxin redox properties by intramolecular hydrogen bondsA Glutathione-independent Glyoxalase of the DJ-1 Superfamily Plays an Important Role in Managing Metabolically Generated Methylglyoxal in Candida albicansUse of cysteine-reactive cross-linkers to probe conformational flexibility of human DJ-1 demonstrates that Glu18 mutations are dimersStereospecific mechanism of DJ-1 glyoxalases inferred from their hemithioacetal-containing crystal structuresSulfenic acid chemistry, detection and cellular lifetimeThe unique functional role of the C-HS hydrogen bond in the substrate specificity and enzyme catalysis of type 1 methionine aminopeptidase.Engineered disulfide bonds restore chaperone-like function of DJ-1 mutants linked to familial Parkinson's disease.Effect of single amino acid substitution on oxidative modifications of the Parkinson's disease-related protein, DJ-1Site-specific mapping and quantification of protein S-sulphenylation in cells.Monomer DJ-1 and its N-terminal sequence are necessary for mitochondrial localization of DJ-1 mutants.Cysteine-mediated redox signaling: chemistry, biology, and tools for discoveryThe role of cysteine oxidation in DJ-1 function and dysfunction.Deciphering the role of histidine 252 in mycobacterial adenosine 5'-phosphosulfate (APS) reductase catalysis.Substrate-mediated fidelity mechanism ensures accurate decoding of proline codons.Aging--RNA in development and disease.SufB intein of Mycobacterium tuberculosis as a sensor for oxidative and nitrosative stresses.Dopamine-derived quinones affect the structure of the redox sensor DJ-1 through modifications at Cys-106 and Cys-53A low pKa cysteine at the active site of mouse methionine sulfoxide reductase AOxidant-induced Interprotein Disulfide Formation in Cardiac Protein DJ-1 Occurs via an Interaction with Peroxiredoxin 2.Oxidation and interaction of DJ-1 with 20S proteasome in the erythrocytes of early stage Parkinson's disease patients.Dissection of the dimerization modes in the DJ-1 superfamily.Toxoplasma DJ-1 Regulates Organelle Secretion by a Direct Interaction with Calcium-Dependent Protein Kinase 1.Proteomic profiling of nitrosative stress: protein S-oxidation accompanies S-nitrosylation.Oxidized DJ-1 as a possible biomarker of Parkinson's diseaseCysteine-mediated redox signalling in the mitochondria.Human Frataxin Folds Via an Intermediate State. Role of the C-Terminal Region.Protein DJ-1 and its anti-oxidative stress function play an important role in renal cell mediated response to profibrotic agents.Short Carboxylic Acid-Carboxylate Hydrogen Bonds Can Have Fully Localized Protons.Novel Redox-Dependent Esterase Activity (EC 3.1.1.2) for DJ-1: Implications for Parkinson's Disease.
P2860
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P2860
Cysteine p K a Depression by a Protonated Glutamic Acid in Human DJ-1 † ‡
description
2008 nî lūn-bûn
@nan
2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Cysteine p K a Depression by a Protonated Glutamic Acid in Human DJ-1 † ‡
@ast
Cysteine p K a Depression by a Protonated Glutamic Acid in Human DJ-1 † ‡
@en
Cysteine p K a Depression by a Protonated Glutamic Acid in Human DJ-1 † ‡
@nl
type
label
Cysteine p K a Depression by a Protonated Glutamic Acid in Human DJ-1 † ‡
@ast
Cysteine p K a Depression by a Protonated Glutamic Acid in Human DJ-1 † ‡
@en
Cysteine p K a Depression by a Protonated Glutamic Acid in Human DJ-1 † ‡
@nl
altLabel
Cysteine pKa depression by a protonated glutamic acid in human DJ-1.
@en
Cysteine pKaDepression by a Protonated Glutamic Acid in Human DJ-1†‡
@en
prefLabel
Cysteine p K a Depression by a Protonated Glutamic Acid in Human DJ-1 † ‡
@ast
Cysteine p K a Depression by a Protonated Glutamic Acid in Human DJ-1 † ‡
@en
Cysteine p K a Depression by a Protonated Glutamic Acid in Human DJ-1 † ‡
@nl
P2860
P50
P3181
P356
P1433
P1476
Cysteine p K a Depression by a Protonated Glutamic Acid in Human DJ-1 † ‡
@en
P2860
P304
P3181
P356
10.1021/BI800282D
P4011
4d99bd449866c2fbbbf857b1f0f688bf38f430f2
P407
P577
2008-07-15T00:00:00Z