Crystal Structure of Coxsackievirus B3 3Dpol Highlights the Functional Importance of Residue 5 in Picornavirus Polymerases
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RNA-Dependent RNA Polymerases of Picornaviruses: From the Structure to Regulatory MechanismsPicornavirus RNA polyadenylation by 3D(pol), the viral RNA-dependent RNA polymeraseStructures of EV71 RNA-dependent RNA polymerase in complex with substrate and analogue provide a drug target against the hand-foot-and-mouth disease pandemic in ChinaStructures of coxsackievirus, rhinovirus, and poliovirus polymerase elongation complexes solved by engineering RNA mediated crystal contactsDistinct Conformations of a Putative Translocation Element in Poliovirus PolymeraseThe Crystal Structure of a Cardiovirus RNA-Dependent RNA Polymerase Reveals an Unusual Conformation of the Polymerase Active SiteThe RNA template channel of the RNA-dependent RNA polymerase as a target for development of antiviral therapy of multiple genera within a virus familyFidelity variants of RNA dependent RNA polymerases uncover an indirect, mutagenic activity of amiloride compounds.Cytoplasmic viral RNA-dependent RNA polymerase disrupts the intracellular splicing machinery by entering the nucleus and interfering with Prp8Novel roles of the picornaviral 3D polymerase in viral pathogenesis.Structure-function relationships underlying the replication fidelity of viral RNA-dependent RNA polymerases.Computational Analysis of Amiloride Analogue Inhibitors of Coxsackievirus B3 RNA Polymerase.Coxsackievirus B3 mutator strains are attenuated in vivo.Highly similar structural frames link the template tunnel and NTP entry tunnel to the exterior surface in RNA-dependent RNA polymerases.Polyprotein context regulates the activity of poliovirus 2CATPase bound to bilayer nanodiscs.Structural features of a picornavirus polymerase involved in the polyadenylation of viral RNA.Homology-Based Identification of a Mutation in the Coronavirus RNA-Dependent RNA Polymerase That Confers Resistance to Multiple MutagensA quantitative stopped-flow fluorescence assay for measuring polymerase elongation ratesSUMO Modification Stabilizes Enterovirus 71 Polymerase 3D To Facilitate Viral Replication.Ribavirin-resistant variants of foot-and-mouth disease virus: the effect of restricted quasispecies diversity on viral virulence.Expanding knowledge of P3 proteins in the poliovirus lifecycle.Attenuation of Foot-and-Mouth Disease Virus by Engineered Viral Polymerase Fidelity.Picornaviral polymerase structure, function, and fidelity modulation.Dominant CD4-dependent RNA-dependent RNA polymerase-specific T-cell responses in children acutely infected with human enterovirus 71 and healthy adult controls.Crystal Structure and Thermostability Characterization of Enterovirus D68 3Dpol.Identification of tolerated insertion sites in poliovirus non-structural proteinsHydrophobic and charged residues in the C-terminal arm of hepatitis C virus RNA-dependent RNA polymerase regulate initiation and elongation.Poliovirus polymerase residue 5 plays a critical role in elongation complex stability.A template RNA entry channel in the fingers domain of the poliovirus polymerase.
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P2860
Crystal Structure of Coxsackievirus B3 3Dpol Highlights the Functional Importance of Residue 5 in Picornavirus Polymerases
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Crystal Structure of Coxsackie ...... 5 in Picornavirus Polymerases
@ast
Crystal Structure of Coxsackie ...... 5 in Picornavirus Polymerases
@en
Crystal Structure of Coxsackie ...... 5 in Picornavirus Polymerases
@nl
type
label
Crystal Structure of Coxsackie ...... 5 in Picornavirus Polymerases
@ast
Crystal Structure of Coxsackie ...... 5 in Picornavirus Polymerases
@en
Crystal Structure of Coxsackie ...... 5 in Picornavirus Polymerases
@nl
prefLabel
Crystal Structure of Coxsackie ...... 5 in Picornavirus Polymerases
@ast
Crystal Structure of Coxsackie ...... 5 in Picornavirus Polymerases
@en
Crystal Structure of Coxsackie ...... 5 in Picornavirus Polymerases
@nl
P2093
P2860
P356
P1433
P1476
Crystal Structure of Coxsackie ...... 5 in Picornavirus Polymerases
@en
P2093
Grace Campagnola
Kirsten Scoggin
Mark Weygandt
Olve Peersen
P2860
P304
P356
10.1128/JVI.00647-08
P577
2008-10-01T00:00:00Z