An inhibitor of FtsZ with potent and selective anti-staphylococcal activity - Wikidata - awgldk - TriplyDB

An inhibitor of FtsZ with potent and selective anti-staphylococcal activity

An inhibitor of FtsZ with potent and selective anti-staphylococcal activity

http://www.wikidata.org/entity/Q27652237

about

3D-SIM super resolution microscopy reveals a bead-like arrangement for FtsZ and the division machinery: implications for triggering cytokinesis A cell-based screen reveals that the albendazole metabolite, albendazole sulfone, targets Wolbachia Molecular docking and ligand specificity in fragment-based inhibitor discovery Restoring methicillin-resistant Staphylococcus aureus susceptibility to β-lactam antibiotics Structural Change in FtsZ Induced by Intermolecular Interactions between Bound GTP and the T7 Loop Structural reorganization of the bacterial cell-division protein FtsZ from Staphylococcus aureus Targeting the Wolbachia cell division protein FtsZ as a new approach for antifilarial therapy Artificial polyploidy improves bacterial single cell genome recovery Relacin, a novel antibacterial agent targeting the Stringent Response Rational design of berberine-based FtsZ inhibitors with broad-spectrum antibacterial activity Variations in the binding pocket of an inhibitor of the bacterial division protein FtsZ across genotypes and species Screening for FtsZ Dimerization Inhibitors Using Fluorescence Cross-Correlation Spectroscopy and Surface Resonance Plasmon Analysis Screening and Development of New Inhibitors of FtsZ from M. Tuberculosis A flexible C-terminal linker is required for proper FtsZ assembly in vitro and cytokinetic ring formation in vivo Streptomyces: a screening tool for bacterial cell division inhibitors Antibiotics for emerging pathogens Newer antibacterial drugs for a new century.FtsZ in bacterial cytokinesis: cytoskeleton and force generator all in one.High throughput 3D super-resolution microscopy reveals Caulobacter crescentus in vivo Z-ring organization.Proliferation of Listeria monocytogenes L-form cells by formation of internal and external vesicles.Comparison of small molecule inhibitors of the bacterial cell division protein FtsZ and identification of a reliable cross-species inhibitor.Characterization of ftsZ mutations that render Bacillus subtilis resistant to MinC A Thiazole Orange Derivative Targeting the Bacterial Protein FtsZ Shows Potent Antibacterial Activity Postgenomic strategies in antibacterial drug discovery.Challenges of antibacterial discovery Coral-mucus-associated Vibrio integrons in the Great Barrier Reef: genomic hotspots for environmental adaptation The pH dependence of polymerization and bundling by the essential bacterial cytoskeletal protein FtsZ N-O chemistry for antibiotics: discovery of N-alkyl-N-(pyridin-2-yl)hydroxylamine scaffolds as selective antibacterial agents using nitroso Diels-Alder and ene chemistry.Chrysophaentins A-H, antibacterial bisdiarylbutene macrocycles that inhibit the bacterial cell division protein FtsZ.Oligochlorophens are potent inhibitors of Bacillus anthracis Drug discovery targeting cell division proteins, microtubules and FtsZ.Antibiotics and bacterial resistance in the 21st century.Bacterial tubulin distinct loop sequences and primitive assembly properties support its origin from a eukaryotic tubulin ancestor.Structure-based design and screening of inhibitors for an essential bacterial GTPase, Der.Antibiotic acyldepsipeptides activate ClpP peptidase to degrade the cell division protein FtsZ Failsafe mechanisms couple division and DNA replication in bacteria.Inhibition of cell division induced by external guide sequences (EGS Technology) targeting ftsZ Discovery of anti-TB agents that target the cell-division protein FtsZ.Systems-level antimicrobial drug and drug synergy discovery.Overcoming resistance to β-lactam antibiotics.

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P2860

An inhibitor of FtsZ with potent and selective anti-staphylococcal activity

http://www.wikidata.org/entity/Q27652237

description

2008 nî lūn-bûn

@nan

2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

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2008年論文

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2008年论文

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name

An inhibitor of FtsZ with potent and selective anti-staphylococcal activity

@ast

An inhibitor of FtsZ with potent and selective anti-staphylococcal activity

@en

An inhibitor of FtsZ with potent and selective anti-staphylococcal activity

@nl

type

label

An inhibitor of FtsZ with potent and selective anti-staphylococcal activity

@ast

An inhibitor of FtsZ with potent and selective anti-staphylococcal activity

@en

An inhibitor of FtsZ with potent and selective anti-staphylococcal activity

@nl

prefLabel

An inhibitor of FtsZ with potent and selective anti-staphylococcal activity

@ast

An inhibitor of FtsZ with potent and selective anti-staphylococcal activity

@en

An inhibitor of FtsZ with potent and selective anti-staphylococcal activity

@nl

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An inhibitor of FtsZ with potent and selective anti-staphylococcal activity

@en

P2093

Amit Taneja

http://www.w3.org/2001/XMLSchema#string

Anil Srivastava

http://www.w3.org/2001/XMLSchema#string

David J Haydon

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David R Brown

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David W Rice

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Greta Galbraith

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Ian Collins

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James M Bennett

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Jonathan R Heal

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Joseph M Sheridan

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P2860

Structural insights into the conformational variability of FtsZ

Preclinical evaluation of novel antibacterial agents by microbiological and molecular techniques

Cytokinesis in bacteria

How Taxol stabilises microtubule structure.

Structural basis for the interaction of tubulin with proteins and drugs that affect microtubule dynamics.

The prokaryotic cytoskeleton: a putative target for inhibitors and antibiotics?

Cell-division inhibitors: new insights for future antibiotics.

Targeting cell division: small-molecule inhibitors of FtsZ GTPase perturb cytokinetic ring assembly and induce bacterial lethality.

Discovery of a small molecule that inhibits cell division by blocking FtsZ, a novel therapeutic target of antibiotics.

Novel inhibitors of bacterial cytokinesis identified by a cell-based antibiotic screening assay.

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2866920

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10.1126/SCIENCE.1159961

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18801997

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