Potent HIV-1 protease inhibitors incorporating meso-bicyclic urethanes as P2-ligands: structure-based design, synthesis, biological evaluation and protein–ligand X-ray studies

Potent HIV-1 protease inhibitors incorporating meso-bicyclic urethanes as P2-ligands: structure-based design, synthesis, biological evaluation and protein–ligand X-ray studies

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http://www.wikidata.org/entity/Q27652460
Optimized hydrophobic interactions and hydrogen bonding at the target-ligand interface leads the pathways of drug-designingHarnessing nature's insight: design of aspartyl protease inhibitors from treatment of drug-resistant HIV to Alzheimer's disease.Novel HIV-1 protease inhibitors (PIs) containing a bicyclic P2 functional moiety, tetrahydropyrano-tetrahydrofuran, that are potent against multi-PI-resistant HIV-1 variantsSynthesis and biological evaluation of novel allophenylnorstatine-based HIV-1 protease inhibitors incorporating high affinity P2-ligands.HIV-1 Protease: Structural Perspectives on Drug ResistanceTetrahydrofuran, tetrahydropyran, triazoles and related heterocyclic derivatives as HIV protease inhibitors.Enhancing protein backbone binding--a fruitful concept for combating drug-resistant HIV.Recent Progress in the Development of HIV-1 Protease Inhibitors for the Treatment of HIV/AIDS
P2860

Potent HIV-1 protease inhibitors incorporating meso-bicyclic urethanes as P2-ligands: structure-based design, synthesis, biological evaluation and protein–ligand X-ray studies

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http://www.wikidata.org/entity/Q27652460
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Potent HIV-1 protease inhibito ...... d protein–ligand X-ray studies
@ast
Potent HIV-1 protease inhibito ...... d protein–ligand X-ray studies
@en
Potent HIV-1 protease inhibito ...... d protein–ligand X-ray studies
@nl
type
label
Potent HIV-1 protease inhibito ...... d protein–ligand X-ray studies
@ast
Potent HIV-1 protease inhibito ...... d protein–ligand X-ray studies
@en
Potent HIV-1 protease inhibito ...... d protein–ligand X-ray studies
@nl
prefLabel
Potent HIV-1 protease inhibito ...... d protein–ligand X-ray studies
@ast
Potent HIV-1 protease inhibito ...... d protein–ligand X-ray studies
@en
Potent HIV-1 protease inhibito ...... d protein–ligand X-ray studies
@nl
P1433
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P2093
P2860
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P356
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P5875
P698
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P1433
P1476
Potent HIV-1 protease inhibito ...... d protein-ligand X-ray studies
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P921
P932