A D-pathway mutation decouples the Paracoccus denitrificans cytochrome c oxidase by altering the side-chain orientation of a distant conserved glutamate
about
Crystallographic and online spectral evidence for role of conformational change and conserved water in cytochrome oxidase proton pumpCopper active sites in biologyMicroscopic basis for kinetic gating in Cytochrome c oxidase: insights from QM/MM analysis.Exploration of the cytochrome c oxidase pathway puzzle and examination of the origin of elusive mutational effects.The K(C) channel in the cbb3-type respiratory oxygen reductase from Rhodobacter capsulatus is required for both chemical and pumped protonsPartial steps of charge translocation in the nonpumping N139L mutant of Rhodobacter sphaeroides cytochrome c oxidase with a blocked D-channel.Decoupling mutations in the D-channel of the aa(3)-type cytochrome c oxidase from Rhodobacter sphaeroides suggest that a continuous hydrogen-bonded chain of waters is essential for proton pumping.Intricate role of water in proton transport through cytochrome c oxidase.Alternative initial proton acceptors for the D pathway of Rhodobacter sphaeroides cytochrome c oxidase.Modulation of the active site conformation by site-directed mutagenesis in cytochrome c oxidase from Paracoccus denitrificans.Communication between R481 and Cu(B) in cytochrome bo(3) ubiquinol oxidase from Escherichia coli.A conserved asparagine in a P-type proton pump is required for efficient gating of protons.The cytochrome ba3 oxygen reductase from Thermus thermophilus uses a single input channel for proton delivery to the active site and for proton pumping.Coupled electron and proton transfer reactions during the O→E transition in bovine cytochrome c oxidase.Current advances in research of cytochrome c oxidase.Structural Changes and Proton Transfer in Cytochrome c Oxidase.Biochemical and biophysical characterization of the two isoforms of cbb3-type cytochrome c oxidase from Pseudomonas stutzeriProton-transport mechanisms in cytochrome c oxidase revealed by studies of kinetic isotope effects.Similarity of cytochrome c oxidases in different organisms.Molecular dynamics simulation of water in cytochrome c oxidase reveals two water exit pathways and the mechanism of transport.A pathogenic mutation in cytochrome c oxidase results in impaired proton pumping while retaining O(2)-reduction activity.Understanding the essential proton-pumping kinetic gates and decoupling mutations in cytochrome c oxidase.Cavity hydration dynamics in cytochrome c oxidase and functional implications.Membrane proteins take center stage in Frankfurt.Mutations in the D-channel of cytochrome c oxidase causes leakage of the proton pump.
P2860
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P2860
A D-pathway mutation decouples the Paracoccus denitrificans cytochrome c oxidase by altering the side-chain orientation of a distant conserved glutamate
description
2008 nî lūn-bûn
@nan
2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
A D-pathway mutation decouples ...... a distant conserved glutamate
@ast
A D-pathway mutation decouples ...... a distant conserved glutamate
@en
A D-pathway mutation decouples ...... a distant conserved glutamate
@nl
type
label
A D-pathway mutation decouples ...... a distant conserved glutamate
@ast
A D-pathway mutation decouples ...... a distant conserved glutamate
@en
A D-pathway mutation decouples ...... a distant conserved glutamate
@nl
prefLabel
A D-pathway mutation decouples ...... a distant conserved glutamate
@ast
A D-pathway mutation decouples ...... a distant conserved glutamate
@en
A D-pathway mutation decouples ...... a distant conserved glutamate
@nl
P2093
P1476
A D-pathway mutation decouples ...... a distant conserved glutamate
@en
P2093
Bernd Ludwig
Elena Olkhova
Guohong Peng
Hannelore Müller
Hartmut Michel
Heike Angerer
Juergen Koepke
Katharina L Dürr
Oliver-Matthias H Richter
P304
P356
10.1016/J.JMB.2008.09.074
P407
P577
2008-12-26T00:00:00Z