Three-dimensional structure of the elastase of Pseudomonas aeruginosa at 1.5-A resolution
about
The metzincins--topological and sequential relations between the astacins, adamalysins, serralysins, and matrixins (collagenases) define a superfamily of zinc-peptidasesCrystal Structure of the Protealysin Precursor: INSIGHTS INTO PROPEPTIDE FUNCTIONStructure of Gentlyase, the neutral metalloprotease ofPaenibacillus polymyxaDissecting the Machinery That Introduces Disulfide Bonds in Pseudomonas aeruginosaEffects of Glycosylation on the Enzymatic Activity and Mechanisms of ProteasesEfficient production and processing of elastase and LasA by Pseudomonas aeruginosa require zinc and calcium ionsTetanus toxin is a zinc protein and its inhibition of neurotransmitter release and protease activity depend on zincHighly sensitive quenched fluorescent substrate of Legionella major secretory protein (msp) based on its structural analysis.Characterization of a periplasmic thiol:disulfide interchange protein required for the functional maturation of secreted virulence factors of Vibrio choleraeProteome analysis of the effect of mucoid conversion on global protein expression in Pseudomonas aeruginosa strain PAO1 shows induction of the disulfide bond isomerase, dsbA.Role of α-helical structure in organic solvent-activated homodimer of elastase strain K.Bacterial extracellular zinc-containing metalloproteasesCarboxylate binding modes in zinc proteins: a theoretical studyThe Pseudomonas aeruginosa flagellum confers resistance to pulmonary surfactant protein-A by impacting the production of exoproteases through quorum-sensingAntagonism of a zinc metalloprotease using a unique metal-chelating scaffold: tropolones as inhibitors of P. aeruginosa elastase.Mechanistic insights into elastin degradation by pseudolysin, the major virulence factor of the opportunistic pathogen Pseudomonas aeruginosa.A comprehensive alanine-scanning mutagenesis study reveals roles for salt bridges in the structure and activity of Pseudomonas aeruginosa elastase.Identification of Pseudolysin (lasB) as an Aciduric Gluten-Degrading Enzyme with High Therapeutic Potential for Celiac DiseaseA substitution at His-120 in the LasA protease of Pseudomonas aeruginosa blocks enzymatic activity without affecting propeptide processing or extracellular secretionFurther molecular characterization of the cloned Legionella pneumophila zinc metalloprotease.The LasB Elastase of Pseudomonas aeruginosa Acts in Concert with Alkaline Protease AprA To Prevent Flagellin-Mediated Immune Recognition.Pseudomonas aeruginosa lasB1 mutants produce an elastase, substituted at active-site His-223, that is defective in activity, processing, and secretion.Cocatalytic zinc motifs in enzyme catalysis.Substitution of active-site His-223 in Pseudomonas aeruginosa elastase and expression of the mutated lasB alleles in Escherichia coli show evidence for autoproteolytic processing of proelastase.The type II secretion system: biogenesis, molecular architecture and mechanism.Expression of virus-encoded proteinases: functional and structural similarities with cellular enzymesCold adaptation of zinc metalloproteases in the thermolysin family from deep sea and arctic sea ice bacteria revealed by catalytic and structural properties and molecular dynamics: new insights into relationship between conformational flexibility anSite-directed mutagenesis of Glu-141 and His-223 in Pseudomonas aeruginosa elastase: catalytic activity, processing, and protective activity of the elastase against Pseudomonas infection.Cloning of a metalloprotease gene involved in the virulence mechanism of Vibrio anguillarum.Role of intermolecular disulfide bonds of the organic solvent-stable PST-01 protease in its organic solvent stability.DsbA and DsbC affect extracellular enzyme formation in Pseudomonas aeruginosa.Purification, characterization, and primary structure of Clostridium perfringens lambda-toxin, a thermolysin-like metalloprotease.Identification of neutralizing epitopes on Pseudomonas aeruginosa elastase and effects of cross-reactions on other thermolysin-like proteases.Target cell contact triggers expression and polarized transfer of Yersinia YopE cytotoxin into mammalian cells.Effect of Pseudomonas aeruginosa elastase B on level and activity of immune proteins/peptides of Galleria mellonella hemolymph.Evidence that Asn542 of neprilysin (EC 3.4.24.11) is involved in binding of the P2' residue of substrates and inhibitors.Structural analysis of zinc substitutions in the active site of thermolysin.Binding to thermolysin of phenolate-containing inhibitors necessitates a revised mechanism of catalysis.Capillary-seeding crystallization and preliminary crystallographic analysis of a solvent-tolerant elastase from Pseudomonas aeruginosa strain K.Identification of glutamate-169 as the third zinc-binding residue in proteinase III, a member of the family of insulin-degrading enzymes.
P2860
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P2860
Three-dimensional structure of the elastase of Pseudomonas aeruginosa at 1.5-A resolution
description
1991 nî lūn-bûn
@nan
1991 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
Three-dimensional structure of the elastase of Pseudomonas aeruginosa at 1.5-A resolution
@ast
Three-dimensional structure of the elastase of Pseudomonas aeruginosa at 1.5-A resolution
@en
Three-dimensional structure of the elastase of Pseudomonas aeruginosa at 1.5-A resolution
@nl
type
label
Three-dimensional structure of the elastase of Pseudomonas aeruginosa at 1.5-A resolution
@ast
Three-dimensional structure of the elastase of Pseudomonas aeruginosa at 1.5-A resolution
@en
Three-dimensional structure of the elastase of Pseudomonas aeruginosa at 1.5-A resolution
@nl
prefLabel
Three-dimensional structure of the elastase of Pseudomonas aeruginosa at 1.5-A resolution
@ast
Three-dimensional structure of the elastase of Pseudomonas aeruginosa at 1.5-A resolution
@en
Three-dimensional structure of the elastase of Pseudomonas aeruginosa at 1.5-A resolution
@nl
P2093
P1476
Three-dimensional structure of the elastase of Pseudomonas aeruginosa at 1.5-A resolution
@en
P2093
K M Flaherty
M M Thayer
P304
P407
P577
1991-02-15T00:00:00Z