Think twice: understanding the high potency of bis(phenyl)methane inhibitors of thrombin
about
Water in cavity-ligand recognition.Experimental and computational active site mapping as a starting point to fragment-based lead discoveryBeyond heparinization: design of highly potent thrombin inhibitors suitable for surface couplingThermodynamics of protein-ligand interactions as a reference for computational analysis: how to assess accuracy, reliability and relevance of experimental dataBoosting Affinity by Correct Ligand Preorganization for the S2 Pocket of Thrombin: A Study by Isothermal Titration Calorimetry, Molecular Dynamics, and High-Resolution Crystal StructuresSite Identification by Ligand Competitive Saturation (SILCS) simulations for fragment-based drug designSurvey of the year 2009: applications of isothermal titration calorimetry.Stacking with No Planarity?Reproducing crystal binding modes of ligand functional groups using Site-Identification by Ligand Competitive Saturation (SILCS) simulationsMarine Diterpenes: Molecular Modeling of Thrombin Inhibitors with Potential Biotechnological Application as an Antithrombotic.A systematic analysis of atomic protein-ligand interactions in the PDB.Rapid decomposition and visualisation of protein-ligand binding free energies by residue and by water.
P2860
Q24618521-8B2ED0DB-C370-4CDB-8723-5838C12358AAQ27676521-1EAC07E8-09AE-4034-B05D-8E6D365DAC7DQ27682019-471A27BB-C8AA-415B-8987-18DA5E87B4B5Q27702163-427D954B-1A1F-4DA2-8912-528AC651E56DQ27703608-7C5C430C-6BC8-47AA-9091-AE1D4EDD56E9Q35566613-DE4B2524-22B5-4273-8FBE-9D15039C84D9Q37820930-AF2DAFC4-0CE9-4477-A612-1F096737896AQ40277037-657887D5-C998-414B-8A13-880084B774FFQ42130025-41DAAA20-60DF-4AC1-95D7-AD809B43B204Q42314217-29B66A78-DF41-4708-8BC9-FEBA65CEF6D7Q47098164-223560EA-9259-4570-93AA-D31C3737174BQ51021008-07F4CD81-2B4A-4C7F-9938-EA24A890E1A3
P2860
Think twice: understanding the high potency of bis(phenyl)methane inhibitors of thrombin
description
2009 nî lūn-bûn
@nan
2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2009年の論文
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2009年論文
@yue
2009年論文
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2009年論文
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2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Think twice: understanding the high potency of bis(phenyl)methane inhibitors of thrombin
@ast
Think twice: understanding the high potency of bis(phenyl)methane inhibitors of thrombin
@en
Think twice: understanding the high potency of bis(phenyl)methane inhibitors of thrombin
@nl
type
label
Think twice: understanding the high potency of bis(phenyl)methane inhibitors of thrombin
@ast
Think twice: understanding the high potency of bis(phenyl)methane inhibitors of thrombin
@en
Think twice: understanding the high potency of bis(phenyl)methane inhibitors of thrombin
@nl
prefLabel
Think twice: understanding the high potency of bis(phenyl)methane inhibitors of thrombin
@ast
Think twice: understanding the high potency of bis(phenyl)methane inhibitors of thrombin
@en
Think twice: understanding the high potency of bis(phenyl)methane inhibitors of thrombin
@nl
P2093
P1476
Think twice: understanding the high potency of bis(phenyl)methane inhibitors of thrombin
@en
P2093
Andreas Heine
Bernhard Baum
David Hangauer
Laveena Muley
Michael Smolinski
P304
P356
10.1016/J.JMB.2009.06.016
P407
P577
2009-08-21T00:00:00Z