Structural evidence for consecutive Hel308-like modules in the spliceosomal ATPase Brr2
about
Structural basis for functional cooperation between tandem helicase cassettes in Brr2-mediated remodeling of the spliceosomeAn interaction between human Sec63 and nucleoredoxin may provide the missing link between the SEC63 gene and polycystic liver diseaseSF1 and SF2 helicases: family mattersThe organization and contribution of helicases to RNA splicingCryoEM structures of two spliceosomal complexes: starter and dessert at the spliceosome feastFunctional roles of DExD/H-box RNA helicases in Pre-mRNA splicingSki2-like RNA helicase structures: common themes and complex assembliesRNA helicases in splicingRNA helicase proteins as chaperones and remodelersStructural basis for the function of DEAH helicasesPrp43p contains a processive helicase structural architecture with a specific regulatory domainMechanism for Aar2p function as a U5 snRNP assembly factorStructural basis for dual roles of Aar2p in U5 snRNP assemblyStructural Basis of Brr2-Prp8 Interactions and Implications for U5 snRNP Biogenesis and the Spliceosome Active SiteInhibition of RNA helicase Brr2 by the C-terminal tail of the spliceosomal protein Prp8A noncanonical PWI domain in the N-terminal helicase-associated region of the spliceosomal Brr2 proteinStructural studies and the assembly of the heptameric post-translational translocon complexThe highly conserved eukaryotic DRG factors are required for efficient translation in a manner redundant with the putative RNA helicase Slh1A conserved membrane-binding domain targets proteins to organelle contact sites.RNA unwinding by the Trf4/Air2/Mtr4 polyadenylation (TRAMP) complexSpliceosome Structure and FunctionMutations in spliceosomal proteins and retina degenerationThe crystal structure of Mtr4 reveals a novel arch domain required for rRNA processingWinged helix domains with unknown function in Hel308 and related helicases.A novel missense SNRNP200 mutation associated with autosomal dominant retinitis pigmentosa in a Chinese family.The Mtr4 ratchet helix and arch domain both function to promote RNA unwindingBrr2 plays a role in spliceosomal activation in addition to U4/U6 unwinding.BRR2a Affects Flowering Time via FLC SplicingFunctional roles of protein splicing factors.Mutations in Splicing Factor Genes Are a Major Cause of Autosomal Dominant Retinitis Pigmentosa in Belgian FamiliesThe Ski2-family helicase Obelus regulates Crumbs alternative splicing and cell polarity.Brr2p-mediated conformational rearrangements in the spliceosome during activation and substrate repositioningSpliceosome activation: U4 is the path, stem I is the goal, and Prp8 is the keeper. Let's cheer for the ATPase Brr2!Retinitis Pigmentosa Mutations in Bad Response to Refrigeration 2 (Brr2) Impair ATPase and Helicase ActivityContribution of SNRNP200 sequence variations to retinitis pigmentosa.Autosomal-dominant retinitis pigmentosa caused by a mutation in SNRNP200, a gene required for unwinding of U4/U6 snRNAs.High prevalence of mutations affecting the splicing process in a Spanish cohort with autosomal dominant retinitis pigmentosa.The spliceosomal proteome: at the heart of the largest cellular ribonucleoprotein machine.Staying on message: ensuring fidelity in pre-mRNA splicing.Structural analyses of the pre-mRNA splicing machinery
P2860
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P2860
Structural evidence for consecutive Hel308-like modules in the spliceosomal ATPase Brr2
description
2009 nî lūn-bûn
@nan
2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Structural evidence for consecutive Hel308-like modules in the spliceosomal ATPase Brr2
@ast
Structural evidence for consecutive Hel308-like modules in the spliceosomal ATPase Brr2
@en
Structural evidence for consecutive Hel308-like modules in the spliceosomal ATPase Brr2
@nl
type
label
Structural evidence for consecutive Hel308-like modules in the spliceosomal ATPase Brr2
@ast
Structural evidence for consecutive Hel308-like modules in the spliceosomal ATPase Brr2
@en
Structural evidence for consecutive Hel308-like modules in the spliceosomal ATPase Brr2
@nl
prefLabel
Structural evidence for consecutive Hel308-like modules in the spliceosomal ATPase Brr2
@ast
Structural evidence for consecutive Hel308-like modules in the spliceosomal ATPase Brr2
@en
Structural evidence for consecutive Hel308-like modules in the spliceosomal ATPase Brr2
@nl
P2093
P2860
P3181
P356
P1476
Structural evidence for consecutive Hel308-like modules in the spliceosomal ATPase Brr2
@en
P2093
Christine Guthrie
Corina Maeder
James Shanks
Jeffrey A Pleiss
Laura-Oana Bud
Lingdi Zhang
P2860
P2888
P3181
P356
10.1038/NSMB.1625
P577
2009-07-01T00:00:00Z
P5875
P6179
1009328534