Structure-guided directed evolution of alkenyl and arylmalonate decarboxylases
about
Biocatalyst development by directed evolutionEnhancing the thermal robustness of an enzyme by directed evolution: least favorable starting points and inferior mutants can map superior evolutionary pathways.Many pathways in laboratory evolution can lead to improved enzymes: how to escape from local minima.The Enantioselective Dakin-West Reaction.One-pot decarboxylative acylation of N-, O-, S-nucleophiles and peptides with 2,2-disubstituted malonic acids.Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently.Computational tools for the evaluation of laboratory-engineered biocatalysts.Arylmalonate decarboxylase-a highly selective bacterial biocatalyst with unknown function.Sequence-Based Screening for Rare Enzymes: New Insights into the World of AMDases Reveal a Conserved Motif and 58 Novel Enzymes Clustering in Eight Distinct Families.New cofactor supports α,β-unsaturated acid decarboxylation via 1,3-dipolar cycloaddition.Enzymatic enantioselective decarboxylative protonation of heteroaryl malonates.Improvement of the Process Stability of Arylmalonate Decarboxylase by Immobilization for Biocatalytic Profen Synthesis.Synthesis of Thymoquinone-Artemisinin Hybrids: New Potent Antileukemia, Antiviral, and Antimalarial AgentsThe Enantioselective Dakin-West Reaction
P2860
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P2860
Structure-guided directed evolution of alkenyl and arylmalonate decarboxylases
description
2009 nî lūn-bûn
@nan
2009 թուականին հրատարակուած գիտական յօդուած
@hyw
2009 թվականին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Structure-guided directed evolution of alkenyl and arylmalonate decarboxylases
@ast
Structure-guided directed evolution of alkenyl and arylmalonate decarboxylases
@en
Structure-guided directed evolution of alkenyl and arylmalonate decarboxylases
@nl
type
label
Structure-guided directed evolution of alkenyl and arylmalonate decarboxylases
@ast
Structure-guided directed evolution of alkenyl and arylmalonate decarboxylases
@en
Structure-guided directed evolution of alkenyl and arylmalonate decarboxylases
@nl
prefLabel
Structure-guided directed evolution of alkenyl and arylmalonate decarboxylases
@ast
Structure-guided directed evolution of alkenyl and arylmalonate decarboxylases
@en
Structure-guided directed evolution of alkenyl and arylmalonate decarboxylases
@nl
P2093
P3181
P356
P1476
Structure-guided directed evolution of alkenyl and arylmalonate decarboxylases
@en
P2093
Bernhard Hauer
Colin Levy
Jason Micklefield
Krzysztof Okrasa
Mark Goodall
Matthew Wilding
Nina Baudendistel
P304
P3181
P356
10.1002/ANIE.200904112
P407
P50
P577
2009-01-01T00:00:00Z