2-{3-[4-(Alkylsulfinyl)phenyl]-1-benzofuran-5-yl}-5-methyl-1,3,4-oxadiazole derivatives as novel inhibitors of glycogen synthase kinase-3beta with good brain permeability

2-{3-[4-(Alkylsulfinyl)phenyl]-1-benzofuran-5-yl}-5-methyl-1,3,4-oxadiazole derivatives as novel inhibitors of glycogen synthase kinase-3beta with good brain permeability

Item
http://www.wikidata.org/entity/Q27657532
Structure-based virtual screening of glycogen synthase kinase 3β inhibitors: analysis of scoring functions applied to large true actives and decoy sets.Small-Molecule Inhibitors of GSK-3: Structural Insights and Their Application to Alzheimer's Disease ModelsHypothermic Preconditioning Reverses Tau Ontogenesis in Human Cortical Neurons and is Mimicked by Protein Phosphatase 2A Inhibition.Novel Non-phosphorylated Serine 9/21 GSK3β/α Antibodies: Expanding the Tools for Studying GSK3 RegulationGlycogen synthase kinase-3 as a therapeutic target for cognitive dysfunction in neuropsychiatric disorders.Identification of dual kinase inhibitors of CK2 and GSK3β: combined qualitative and quantitative pharmacophore modeling approach.Quantitative Structure-Activity Relationship Analysis and a Combined Ligand-Based/Structure-Based Virtual Screening Study for Glycogen Synthase Kinase-3.A novel glycogen synthase kinase-3 inhibitor 2-methyl-5-(3-{4-[(S )-methylsulfinyl]phenyl}-1-benzofuran-5-yl)-1,3,4-oxadiazole decreases tau phosphorylation and ameliorates cognitive deficits in a transgenic model of Alzheimer's disease.Design, Synthesis and Bioactivity Evaluation of Novel β-carboline 1,3,4-oxadiazole Derivatives.Synthesis and preliminary characterization of radioiodinated benzofuran-3-yl-(indol-3-yl)maleimide derivatives as potential SPECT imaging probes for the detection of glycogen synthase kinase-3β (GSK-3β) in the brain.Total synthesis of diptoindonesin G and its analogues as selective modulators of estrogen receptors.Role of bridging water molecules in GSK3β-inhibitor complexes: insights from QM/MM, MD, and molecular docking studies.Synthesis of Novel Pyrimidin-4-One Bearing Piperazine Ring-Based Amides as Glycogen Synthase Kinase-3β Inhibitors with Antidepressant Activity.Oxadiazole-2-thiol adsorption on gold nanorods: a joint theoretical and experimental study by using SERS, XPS, and DFT
P2860

2-{3-[4-(Alkylsulfinyl)phenyl]-1-benzofuran-5-yl}-5-methyl-1,3,4-oxadiazole derivatives as novel inhibitors of glycogen synthase kinase-3beta with good brain permeability

Item
http://www.wikidata.org/entity/Q27657532
description
2009 nî lūn-bûn
@nan
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
2-{3-[4-(Alkylsulfinyl)phenyl] ...... a with good brain permeability
@ast
2-{3-[4-(Alkylsulfinyl)phenyl] ...... a with good brain permeability
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2-{3-[4-(Alkylsulfinyl)phenyl] ...... a with good brain permeability
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type
label
2-{3-[4-(Alkylsulfinyl)phenyl] ...... a with good brain permeability
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2-{3-[4-(Alkylsulfinyl)phenyl] ...... a with good brain permeability
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2-{3-[4-(Alkylsulfinyl)phenyl] ...... a with good brain permeability
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prefLabel
2-{3-[4-(Alkylsulfinyl)phenyl] ...... a with good brain permeability
@ast
2-{3-[4-(Alkylsulfinyl)phenyl] ...... a with good brain permeability
@en
2-{3-[4-(Alkylsulfinyl)phenyl] ...... a with good brain permeability
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2-{3-[4-(Alkylsulfinyl)phenyl] ...... a with good brain permeability
@en
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P921