Structural basis of activation-dependent binding of ligand-mimetic antibody AL-57 to integrin LFA-1

Structural basis of activation-dependent binding of ligand-mimetic antibody AL-57 to integrin LFA-1

Item
http://www.wikidata.org/entity/Q27657681
Stable Coordination of the Inhibitory Ca2+ Ion at the Metal Ion-Dependent Adhesion Site in Integrin CD11b/CD18 by an Antibody-Derived Ligand Aspartate: Implications for Integrin Regulation and Structure-Based Drug DesignStructure ofStreptococcus agalactiaetip pilin GBS104: a model for GBS pili assembly and host interactionsSmall molecule agonists of integrin CD11b/CD18 do not induce global conformational changes and are significantly better than activating antibodies in reducing vascular injury.Dynamic structural changes are observed upon collagen and metal ion binding to the integrin α1 I domain.CSL311, a novel, potent, therapeutic monoclonal antibody for the treatment of diseases mediated by the common β chain of the IL-3, GM-CSF and IL-5 receptorsSevoflurane binds and allosterically blocks integrin lymphocyte function-associated antigen-1.Selective Targeting of High-Affinity LFA-1 Does Not Augment Costimulation Blockade in a Nonhuman Primate Renal Transplantation Model.Structure and dynamics of the integrin LFA-1 I-domain in the inactive state underlie its inside-out/outside-in signaling and allosteric mechanisms.Crystal structure of the antigen-binding fragment of a monoclonal antibody specific for the multidrug-resistance-linked ABC transporter human P-glycoprotein2E8 binds to the high affinity I-domain in a metal ion-dependent manner: a second generation monoclonal antibody selectively targeting activated LFA-1.NMR characterization of the conformational fluctuations of the human lymphocyte function-associated antigen-1 I-domain
P2860

Structural basis of activation-dependent binding of ligand-mimetic antibody AL-57 to integrin LFA-1

Item
http://www.wikidata.org/entity/Q27657681
description
2009 nî lūn-bûn
@nan
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Structural basis of activation ...... tibody AL-57 to integrin LFA-1
@ast
Structural basis of activation ...... tibody AL-57 to integrin LFA-1
@en
Structural basis of activation ...... tibody AL-57 to integrin LFA-1
@nl
type
label
Structural basis of activation ...... tibody AL-57 to integrin LFA-1
@ast
Structural basis of activation ...... tibody AL-57 to integrin LFA-1
@en
Structural basis of activation ...... tibody AL-57 to integrin LFA-1
@nl
prefLabel
Structural basis of activation ...... tibody AL-57 to integrin LFA-1
@ast
Structural basis of activation ...... tibody AL-57 to integrin LFA-1
@en
Structural basis of activation ...... tibody AL-57 to integrin LFA-1
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P921
P932
P356
P1433
P1476
Structural basis of activation ...... tibody AL-57 to integrin LFA-1
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P921
P932