Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases - Wikidata - awgldk - TriplyDB

Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases

Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases

http://www.wikidata.org/entity/Q27657740

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Structural basis of selective ubiquitination of TRF1 by SCFFbx4 Tumor-suppressor role for the SPOP ubiquitin ligase in signal-dependent proteolysis of the oncogenic co-activator SRC-3/AIB1 The Cullin 3 substrate adaptor KLHL20 mediates DAPK ubiquitination to control interferon responses Ubiquitin ligase activity of Cul3-KLHL7 protein is attenuated by autosomal dominant retinitis pigmentosa causative mutation SPOP promotes tumorigenesis by acting as a key regulatory hub in kidney cancer Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer Cullin 3 Ubiquitin Ligases in Cancer Biology: Functions and Therapeutic Implications Cul3-KLHL20 ubiquitin ligase: physiological functions, stress responses, and disease implications Quantifying ubiquitin signaling Structural Basis for Cul3 Protein Assembly with the BTB-Kelch Family of E3 Ubiquitin Ligases Molecular Architecture of the Ankyrin SOCS Box Family of Cul5-Dependent E3 Ubiquitin Ligases Multimeric Complexes among Ankyrin-Repeat and SOCS-box Protein 9 (ASB9), ElonginBC, and Cullin 5: Insights into the Structure and Assembly of ECS-type Cullin-RING E3 Ubiquitin Ligases Structure of the BTB domain of Keap1 and its interaction with the triterpenoid antagonist CDDO Structural basis of high-order oligomerization of the cullin-3 adaptor SPOP SCFCdc4 enables mating type switching in yeast by cyclin-dependent kinase-mediated elimination of the Ash1 transcriptional repressor.Cullin-RING ubiquitin ligases in salicylic acid-mediated plant immune signaling CSNAP Is a Stoichiometric Subunit of the COP9 Signalosome Cullin3-KLHL15 ubiquitin ligase mediates CtIP protein turnover to fine-tune DNA-end resection Comprehensive assessment of cancer missense mutation clustering in protein structures A SPOPL/Cullin-3 ubiquitin ligase complex regulates endocytic trafficking by targeting EPS15 at endosomes Stabilizing mutations of KLHL24 ubiquitin ligase cause loss of keratin 14 and human skin fragility Conserved properties of Drosophila Insomniac link sleep regulation and synaptic function Emerging role of the ubiquitin proteasome system in the control of shoot apical meristem function(f).Ku and DNA-dependent protein kinase dynamic conformations and assembly regulate DNA binding and the initial non-homologous end joining complex.Hedgehog signaling downregulates suppressor of fused through the HIB/SPOP-Crn axis in Drosophila.Identification and Expression Profiling of the BTB Domain-Containing Protein Gene Family in the Silkworm, Bombyx mori Mechanism and evolution of cytosolic Hedgehog signal transduction Tumor suppressor SPOP ubiquitinates and degrades EglN2 to compromise growth of prostate cancer cells Targeting Cullin-RING E3 ubiquitin ligases for drug discovery: structure, assembly and small-molecule modulation.Evidence for molecular differences in prostate cancer between African American and Caucasian men Twists and turns in ubiquitin-like protein conjugation cascades.Succination of Keap1 and activation of Nrf2-dependent antioxidant pathways in FH-deficient papillary renal cell carcinoma type 2.SPOP suppresses tumorigenesis by regulating Hedgehog/Gli2 signaling pathway in gastric cancer.Transfer of Ho endonuclease and Ufo1 to the proteasome by the UbL-UbA shuttle protein, Ddi1, analysed by complex formation in vitro.Mechanism of cullin3 E3 ubiquitin ligase dimerization.The emerging role of speckle-type POZ protein (SPOP) in cancer development.Identification of a novel germline SPOP mutation in a family with hereditary prostate cancer.A novel bipartite nuclear localization signal guides BPM1 protein to nucleolus suggesting its Cullin3 independent function The instability of the BTB-KELCH protein Gigaxonin causes Giant Axonal Neuropathy and constitutes a new penetrant and specific diagnostic test Identification of speckle-type POZ protein somatic mutations in African American prostate cancer.

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Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases

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2009 nî lūn-bûn

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2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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Structures of SPOP-Substrate C ...... of BTB-Cul3 Ubiquitin Ligases

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Structures of SPOP-Substrate C ...... of BTB-Cul3 Ubiquitin Ligases

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Structures of SPOP-Substrate C ...... of BTB-Cul3 Ubiquitin Ligases

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Structures of SPOP-Substrate C ...... of BTB-Cul3 Ubiquitin Ligases

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Structures of SPOP-Substrate C ...... of BTB-Cul3 Ubiquitin Ligases

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Structures of SPOP-Substrate C ...... of BTB-Cul3 Ubiquitin Ligases

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Structures of SPOP-Substrate C ...... of BTB-Cul3 Ubiquitin Ligases

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Structures of SPOP-Substrate C ...... of BTB-Cul3 Ubiquitin Ligases

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Structures of SPOP-Substrate C ...... of BTB-Cul3 Ubiquitin Ligases

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Structures of SPOP-substrate c ...... of BTB-Cul3 ubiquitin ligases

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Amanda Nourse

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Brenda A Schulman

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Darcie J Miller

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David M Duda

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Helen Walden

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J Wade Harper

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Jiang Liu

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Kevin P White

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M Brett Waddell

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Matthew F Calabrese

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P2860

Cullin-RING ubiquitin ligases: global regulation and activation cycles

Structure of the VHL-ElonginC-ElonginB complex: implications for VHL tumor suppressor function

Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex

Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex

Structure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signaling

Distinct molecular mechanism for initiating TRAF6 signalling

Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery

Structural basis of UV DNA-damage recognition by the DDB1-DDB2 complex

Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair

Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation

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1

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