KIR2DS4 is a product of gene conversion with KIR3DL2 that introduced specificity for HLA-A * 11 while diminishing avidity for HLA-C - Wikidata - awgldk - TriplyDB

KIR2DS4 is a product of gene conversion with KIR3DL2 that introduced specificity for HLA-A * 11 while diminishing avidity for HLA-C

KIR2DS4 is a product of gene conversion with KIR3DL2 that introduced specificity for HLA-A * 11 while diminishing avidity for HLA-C

http://www.wikidata.org/entity/Q27657994

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The shaping of modern human immune systems by multiregional admixture with archaic humans Genome hyperevolution and the success of a parasite The Impact of KIR Polymorphism on the Risk of Developing Cancer: Not as Strong as Imagined?Activating KIRs and NKG2C in Viral Infections: Toward NK Cell Memory?Activating killer cell immunoglobulin-like receptor 2DS2 binds to HLA-A*11 HLA-F and MHC class I open conformers are ligands for NK cell Ig-like receptors Co-evolution of human leukocyte antigen (HLA) class I ligands with killer-cell immunoglobulin-like receptors (KIR) in a genetically diverse population of sub-Saharan Africans Coevolution of killer cell Ig-like receptors with HLA-C to become the major variable regulators of human NK cells Canonical and Cross-reactive Binding of NK Cell Inhibitory Receptors to HLA-C Allotypes Is Dictated by Peptides Bound to HLA-C.The structure of the atypical killer cell immunoglobulin-like receptor, KIR2DL4.KIR2DS4 promotes HIV-1 pathogenesis: new evidence from analyses of immunogenetic data and natural killer cell function Imputation of KIR Types from SNP Variation Data.Uterine Natural Killer Cells: Functional Distinctions and Influence on Pregnancy in Humans and Mice.Self-association of an activating natural killer cell receptor, KIR2DS1 Primate-specific regulation of natural killer cells.DAP12 impacts trafficking and surface stability of killer immunoglobulin-like receptors on natural killer cells Significant association of KIR2DL3-HLA-C1 combination with cerebral malaria and implications for co-evolution of KIR and HLA.Maternal activating KIRs protect against human reproductive failure mediated by fetal HLA-C2.KIR diversity in Māori and Polynesians: populations in which HLA-B is not a significant KIR ligand.Time to seroconversion in HIV-exposed subjects carrying protective versus non protective KIR3DS1/L1 and HLA-B genotypes.Killer immunoglobulin-like receptor (KIR) and HLA genotypes affect the outcome of allogeneic kidney transplantation.Balancing natural killer cell activation through paired receptors.Impact of a functional KIR2DS4 allele on heterosexual HIV-1 transmission among discordant Zambian couples.The structural basis of ligand recognition by natural killer cell receptors.Humans differ from other hominids in lacking an activating NK cell receptor that recognizes the C1 epitope of MHC class I Killer-cell immunoglobulin-like receptor genotyping and HLA killer-cell immunoglobulin-like receptor-ligand identification by real-time polymerase chain reaction KIR2DS5 in the presence of HLA-C C2 protects against endometriosis Analysis of binding of KIR3DS1*014 to HLA suggests distinct evolutionary history of KIR3DS1 Expression of activating KIR2DS2 and KIR2DS4 genes after hematopoietic cell transplantation: relevance to cytomegalovirus infection How does variability of immune system genes affect placentation?Human-specific evolution of killer cell immunoglobulin-like receptor recognition of major histocompatibility complex class I molecules.Revealing mammalian evolutionary relationships by comparative analysis of gene clusters Mutation at positively selected positions in the binding site for HLA-C shows that KIR2DL1 is a more refined but less adaptable NK cell receptor than KIR2DL3.Structural insights into activation of antiviral NK cell responses Genetic (KIR, HLA-C) and Some Clinical Parameters Influencing the Level of Liver Enzymes and Early Virologic Response in Patients with Chronic Hepatitis C Conserved KIR allele-level haplotypes are altered by microvariation in individuals with European ancestry.Killer cell immunoglobulin-like receptor gene associations with autoimmune and allergic diseases, recurrent spontaneous abortion, and neoplasms.Donor killer immunoglobulin-like receptor genes and reactivation of cytomegalovirus after HLA-matched hematopoietic stem-cell transplantation: HLA-C allotype is an essential cofactor Analysis of memory-like natural killer cells in human cytomegalovirus-infected children undergoing αβ+T and B cell-depleted hematopoietic stem cell transplantation for hematological malignancies.The effects of killer cell immunoglobulin-like receptor (KIR) genes on susceptibility to HIV-1 infection in the Polish population.

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KIR2DS4 is a product of gene conversion with KIR3DL2 that introduced specificity for HLA-A * 11 while diminishing avidity for HLA-C

http://www.wikidata.org/entity/Q27657994

description

2009 nî lūn-bûn

@nan

2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

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2009年論文

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2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

KIR2DS4 is a product of gene c ...... diminishing avidity for HLA-C

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KIR2DS4 is a product of gene c ...... diminishing avidity for HLA-C

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KIR2DS4 is a product of gene c ...... diminishing avidity for HLA-C

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type

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KIR2DS4 is a product of gene c ...... diminishing avidity for HLA-C

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KIR2DS4 is a product of gene c ...... diminishing avidity for HLA-C

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KIR2DS4 is a product of gene c ...... diminishing avidity for HLA-C

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prefLabel

KIR2DS4 is a product of gene c ...... diminishing avidity for HLA-C

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KIR2DS4 is a product of gene c ...... diminishing avidity for HLA-C

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KIR2DS4 is a product of gene c ...... diminishing avidity for HLA-C

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Journal of Experimental Medicine

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KIR2DS4 is a product of gene c ...... diminishing avidity for HLA-C

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Anastazia M Older Aguilar

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David A Bushnell

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John A Hammond

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Laurent Abi-Rached

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Lisbeth A Guethlein

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Michael Gleimer

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Peter Parham

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Philip J Robinson

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Thorsten Graef

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P2860

HLA-E-bound peptides influence recognition by inhibitory and triggering CD94/NKG2 receptors: preferential response to an HLA-G-derived nonamer

Cloning of immunoglobulin-superfamily members associated with HLA-C and HLA-B recognition by human natural killer cells

A novel surface molecule homologous to the p58/p50 family of receptors is selectively expressed on a subset of human natural killer cells and induces both triggering of cell functions and proliferation

Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains

MAFFT: a novel method for rapid multiple sequence alignment based on fast Fourier transform

Electrostatics of nanosystems: application to microtubules and the ribosome

The natural killer cell receptor specific for HLA-A allotypes: a novel member of the p58/p70 family of inhibitory receptors that is characterized by three immunoglobulin-like domains and is expressed as a 140-kD disulphide-linked dimer

IMGT/HLA and IMGT/MHC: sequence databases for the study of the major histocompatibility complex

IPD--the Immuno Polymorphism Database

Processing of X-ray diffraction data collected in oscillation mode

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2557-2572

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scholarly article

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4730726

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10.1084/JEM.20091010

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11

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206

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38037671

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19858347

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