The Structure of the Mammalian RNase H2 Complex Provides Insight into RNA{middle dot}DNA Hybrid Processing to Prevent Immune Dysfunction
about
The structural and biochemical characterization of human RNase H2 complex reveals the molecular basis for substrate recognition and Aicardi-Goutières syndrome defectsCrystal Structures of RNase H2 in Complex with Nucleic Acid Reveal the Mechanism of RNA-DNA Junction Recognition and CleavageThe Structure of the Human RNase H2 Complex Defines Key Interaction Interfaces Relevant to Enzyme Function and Human DiseasePCNA directs type 2 RNase H activity on DNA replication and repair substratesRNase H2 roles in genome integrity revealed by unlinking its activitiesActivity, stability, and structure of metagenome-derived LC11-RNase H1, a homolog ofSulfolobus tokodaiiRNase H1Structure and characterization of RNase H3 from Aquifex aeolicusAnalysis of subunit assembly and function of the Saccharomyces cerevisiae RNase H2 complex.Crystal structure of a TAF1-TAF7 complex in human transcription factor IID reveals a promoter binding moduleRole of N-terminal extension of Bacillus stearothermophilus RNase H2 and C-terminal extension of Thermotoga maritima RNase H2.Ribonucleotide incorporation by human DNA polymerase η impacts translesion synthesis and RNase H2 activity.Enzymatic removal of ribonucleotides from DNA is essential for mammalian genome integrity and development.Ribonuclease H2 in health and disease.Identification of host proteins interacting with the integrin-like A domain of Toxoplasma gondii micronemal protein MIC2 by yeast-two-hybrid screening.Reduction of hRNase H2 activity in Aicardi-Goutières syndrome cells leads to replication stress and genome instabilityFunctional consequences of the RNase H2A subunit mutations that cause Aicardi-Goutieres syndrome.The Yin and Yang of R-loop biology.The Balancing Act of Ribonucleotides in DNASynonymous mutations in RNASEH2A create cryptic splice sites impairing RNase H2 enzyme function in Aicardi-Goutières syndrome.Aicardi-Goutières syndrome: clues from the RNase H2 knock-out mouse.Structural studies of RFCCtf18 reveal a novel chromatin recruitment role for Dcc1.Effects of neutral salts and pH on the activity and stability of human RNase H2.Mapping Ribonucleotides Incorporated into DNA by Hydrolytic End-Sequencing.
P2860
Q24319186-AB910AD2-B5B7-455F-9411-075A520F82DBQ27666026-4B89C8ED-78CD-491D-A018-F931FCF3DE5DQ27666373-10F6820A-2912-44FF-85D8-D5AF9F7024FBQ27666608-93153668-8647-4EB6-95CA-3FEDDDB76592Q27676027-D90AAAD8-48B0-4F33-8628-496A8698CBA9Q27677834-581EB00B-60BC-4FFE-967D-33A3E9FAB916Q27681104-9E2F3F62-CE5F-42DF-A413-00E820CCC5E3Q27935271-A8D23719-5433-4E50-AF47-D909349B7DE2Q28116042-80E9C1C7-B293-400E-B18C-010E3EF1FA74Q30352778-DF665E55-EB0D-4209-AC8A-BD8D2804A2B7Q33557461-DDE100AD-6D1C-4E6E-A272-18FDD85B1A2CQ34274334-3F856F3D-F4AA-43B9-89B4-A8B53AF9D8F6Q34433093-C5CDB46A-D379-4BBC-892B-016136664893Q34645558-DB6B723D-C733-43A8-99FA-4ABC1FD61075Q34920730-FB58A60D-989B-4DAF-AF0A-1DCC6E28E8B3Q34947859-C4628474-7C03-48BC-A404-3BE8AAF6F37AQ35908868-009B1D90-59A3-4D1B-8A4F-38AF74935FCDQ36853298-56CED36D-1A3E-44B7-A5A5-3D3008923E2BQ37022007-12A3535E-43C0-480E-A397-ABC8DAE87791Q38112613-9CAAEB37-C1D0-4A44-9D79-A373264730DBQ38966656-6BCF2655-3AB9-4CE3-859F-31CEDE36D857Q46384941-23B97DD8-034C-4396-A20B-AD8E4FE1049EQ50086320-3EABDA14-D863-488D-A9CB-65216D1D5871
P2860
The Structure of the Mammalian RNase H2 Complex Provides Insight into RNA{middle dot}DNA Hybrid Processing to Prevent Immune Dysfunction
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The Structure of the Mammalian ...... to Prevent Immune Dysfunction
@ast
The Structure of the Mammalian ...... to Prevent Immune Dysfunction
@en
The Structure of the Mammalian ...... to Prevent Immune Dysfunction
@nl
type
label
The Structure of the Mammalian ...... to Prevent Immune Dysfunction
@ast
The Structure of the Mammalian ...... to Prevent Immune Dysfunction
@en
The Structure of the Mammalian ...... to Prevent Immune Dysfunction
@nl
prefLabel
The Structure of the Mammalian ...... to Prevent Immune Dysfunction
@ast
The Structure of the Mammalian ...... to Prevent Immune Dysfunction
@en
The Structure of the Mammalian ...... to Prevent Immune Dysfunction
@nl
P2093
P2860
P921
P356
P1476
The Structure of the Mammalian ...... to Prevent Immune Dysfunction
@en
P2093
Fred W Perrino
Nadine M Shaban
Scott Harvey
Thomas Hollis
P2860
P304
P356
10.1074/JBC.M109.059048
P407
P577
2010-02-05T00:00:00Z