Structure of a two-G-tetrad intramolecular G-quadruplex formed by a variant human telomeric sequence in K+ solution: insights into the interconversion of human telomeric G-quadruplex structures - Wikidata - awgldk - TriplyDB

Structure of a two-G-tetrad intramolecular G-quadruplex formed by a variant human telomeric sequence in K+ solution: insights into the interconversion of human telomeric G-quadruplex structures

Structure of a two-G-tetrad intramolecular G-quadruplex formed by a variant human telomeric sequence in K+ solution: insights into the interconversion of human telomeric G-quadruplex structures

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Solution structure of the major G-quadruplex formed in the human VEGF promoter in K+: insights into loop interactions of the parallel G-quadruplexes Solution structure of a 2:1 complex of anticancer drug XR5944 with TFF1 estrogen response element: insights into DNA recognition by a bis-intercalator Mechanical unfolding of human telomere G-quadruplex DNA probed by integrated fluorescence and magnetic tweezers spectroscopy.Coexistence of an ILPR i-motif and a partially folded structure with comparable mechanical stability revealed at the single-molecule level.Structural insights into G-quadruplexes: towards new anticancer drugs.Emulsified BMVC derivative induced filtration for G-quadruplex DNA structural separation Binding of gemini bisbenzimidazole drugs with human telomeric G-quadruplex dimers: effect of the spacer in the design of potent telomerase inhibitors Loss of loop adenines alters human telomere d[AG3(TTAG3)3] quadruplex folding.Bcl-2 promoter sequence G-quadruplex interactions with three planar and non-planar cationic porphyrins: TMPyP4, TMPyP3, and TMPyP2.Explaining the varied glycosidic conformational, G-tract length and sequence preferences for anti-parallel G-quadruplexes Conformation and stability of intramolecular telomeric G-quadruplexes: sequence effects in the loops.Kinetics and mechanism of G-quadruplex formation and conformational switch in a G-quadruplex of PS2.M induced by Pb²⁺G-quadruplex structure and stability illuminated by 2-aminopurine phasor plots Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement.Separation of Quadruplex Polymorphism in DNA Sequences by Reversed-Phase Chromatography.The major G-quadruplex formed in the human platelet-derived growth factor receptor β promoter adopts a novel broken-strand structure in K+ solution.Sequence, stability, and structure of G-quadruplexes and their interactions with drugs Populated intermediates in the thermal unfolding of the human telomeric quadruplex.G-register exchange dynamics in guanine quadruplexes.DNA G-quadruplex and its potential as anticancer drug target A New G-Quadruplex with Hairpin Loop Immediately Upstream of the Human BCL2 P1 Promoter Modulates Transcription.Folding and misfolding pathways of G-quadruplex DNA.Effects of G-Quadruplex Topology on Electronic Transfer Integrals Effect of sequence and metal ions on UVB-induced anti cyclobutane pyrimidine dimer formation in human telomeric DNA sequences.Conformational changes of non-B DNA.G-quadruplexes incorporating modified constituents: a review.G-quadruplex interacting small molecules and drugs: from bench toward bedside.Targeting unimolecular G-quadruplex nucleic acids: a new paradigm for the drug discovery?G-triplex structure and formation propensity.The [Au(9-methylcaffein-8-ylidene)2]+ / DNA Tel23 System: Solution, Computational and Biological Studies.A direct view of the complex multi-pathway folding of telomeric G-quadruplexes.An investigation of G-quadruplex structural polymorphism in the human telomere using a combined approach of hydrodynamic bead modeling and molecular dynamics simulation.Computational and Experimental Studies of ADP-Ribosylation.Folding dynamics and conformational heterogeneity of human telomeric G-quadruplex structures in Na+ solutions by single molecule FRET microscopy Thermodynamic characterization of human telomere quadruplex unfolding Interaction of human telomeric DNA with N-methyl mesoporphyrin IX.Clustered abasic lesions profoundly change the structure and stability of human telomeric G-quadruplexes.Structural dynamics of possible late-stage intermediates in folding of quadruplex DNA studied by molecular simulations.Classification of g-quadruplex DNA on the basis of the quadruplex twist angle and planarity of g-quartets.Identification of small interfering RNA targeting Signal Transducer and Activator of Transcription 6: Characterisation and selection of candidates for pre-clinical development.

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Structure of a two-G-tetrad intramolecular G-quadruplex formed by a variant human telomeric sequence in K+ solution: insights into the interconversion of human telomeric G-quadruplex structures

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Danzhou Yang

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Elizabeth Veliath

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Jixun Dai

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P2860

Crystal structure of parallel quadruplexes from human telomeric DNA

The Hallmarks of Cancer

Extension of life-span by introduction of telomerase into normal human cells

Human telomeres contain at least three types of G-rich repeat distributed non-randomly

Structure of the intramolecular human telomeric G-quadruplex in potassium solution: a novel adenine triple formation

Structure of a human telomeric DNA sequence stabilized by 8-bromoguanosine substitutions, as determined by NMR in a K+ solution

Structure of the Hybrid-2 type intramolecular human telomeric G-quadruplex in K+ solution: insights into structure polymorphism of the human telomeric sequence

Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution

Structure of the Human Telomere in K + Solution: A Stable Basket-Type G-Quadruplex with Only Two G-Tetrad Layers

Solution structure of the human telomeric repeat d[AG3(T2AG3)3] G-tetraplex

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10.1093/NAR/GKP1029

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3

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38

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19946019

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