Binding of a potent small-molecule inhibitor of six-helix bundle formation requires interactions with both heptad-repeats of the RSV fusion protein
about
Small-molecule inhibitors of dengue-virus entryCell entry of enveloped virusesStructure of Respiratory Syncytial Virus Fusion Glycoprotein in the Postfusion Conformation Reveals Preservation of Neutralizing EpitopesDownsizing human, bacterial, and viral proteins to short water-stable alpha helices that maintain biological potencyIdentification of a gp41 core-binding molecule with homologous sequence of human TNNI3K-like protein as a novel human immunodeficiency virus type 1 entry inhibitor.Respiratory syncytial virus: a prioritized or neglected target?Cross-resistance mechanism of respiratory syncytial virus against structurally diverse entry inhibitors.Pharmacokinetics-pharmacodynamics of a respiratory syncytial virus fusion inhibitor in the cotton rat model.Structure and function of respiratory syncytial virus surface glycoproteins.Efficient replication of a paramyxovirus independent of full zippering of the fusion protein six-helix bundle domain.Intranasal administration of maleic anhydride-modified human serum albumin for pre-exposure prophylaxis of respiratory syncytial virus infectionProgress in understanding and controlling respiratory syncytial virus: still crazy after all these yearsAntiviral Activity of TMC353121, a Respiratory Syncytial Virus (RSV) Fusion Inhibitor, in a Non-Human Primate ModelProtein-Protein Interactions of Viroporins in Coronaviruses and Paramyxoviruses: New Targets for Antivirals?Blocking Respiratory Syncytial Virus Entry: A Story with Twists.A generic screening platform for inhibitors of virus induced cell fusion using cellular electrical impedanceA fluorescence polarization assay using an engineered human respiratory syncytial virus F protein as a direct screening platformMolecular mechanism of respiratory syncytial virus fusion inhibitors.Targeting RSV with vaccines and small molecule drugs.A Short Double-Stapled Peptide Inhibits Respiratory Syncytial Virus Entry and Spreading.Mucosal delivery of a double-stapled RSV peptide prevents nasopulmonary infectionRecent developments with live-attenuated recombinant paramyxovirus vaccines.Therapeutic efficacy of a respiratory syncytial virus fusion inhibitorStructure-guided design of small-molecule therapeutics against RSV disease.GS-5806 inhibits pre- to postfusion conformational changes of the respiratory syncytial virus fusion protein.Revealing the binding mode between respiratory syncytial virus fusion protein and benzimidazole-based inhibitors.
P2860
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P2860
Binding of a potent small-molecule inhibitor of six-helix bundle formation requires interactions with both heptad-repeats of the RSV fusion protein
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Binding of a potent small-mole ...... eats of the RSV fusion protein
@ast
Binding of a potent small-mole ...... eats of the RSV fusion protein
@en
Binding of a potent small-mole ...... eats of the RSV fusion protein
@nl
type
label
Binding of a potent small-mole ...... eats of the RSV fusion protein
@ast
Binding of a potent small-mole ...... eats of the RSV fusion protein
@en
Binding of a potent small-mole ...... eats of the RSV fusion protein
@nl
prefLabel
Binding of a potent small-mole ...... eats of the RSV fusion protein
@ast
Binding of a potent small-mole ...... eats of the RSV fusion protein
@en
Binding of a potent small-mole ...... eats of the RSV fusion protein
@nl
P2093
P2860
P356
P1476
Binding of a potent small-mole ...... eats of the RSV fusion protein
@en
P2093
Dirk Roymans
Eric Arnoult
Hendrik L De Bondt
Herman van Vlijmen
Hidong Kim
Jean-François Bonfanti
Koen Andries
Marcia Van Ginderen
Maxwell D Cummings
Nick Verheyen
P2860
P304
P356
10.1073/PNAS.0910108106
P407
P577
2010-01-05T00:00:00Z