DNA stretching in the nucleosome facilitates alkylation by an intercalating antitumour agent
about
CENP-C directs a structural transition of CENP-A nucleosomes mainly through sliding of DNA gyresPerturbations in nucleosome structure from heavy metal associationSpecific DNA structural attributes modulate platinum anticancer drug site selection and cross-link generationLigand substitutions between ruthenium-cymene compounds can control protein versus DNA targeting and anticancer activity.An Organometallic Compound which Exhibits a DNA Topology-Dependent One-Stranded Intercalation ModeDNA architecture, deformability, and nucleosome positioning.A bulky DNA lesion derived from a highly potent polycyclic aromatic tumorigen stabilizes nucleosome core particle structure.Rapid DNA-protein cross-linking and strand scission by an abasic site in a nucleosome core particle.Nucleosome structural studies.Probing interactions between lysine residues in histone tails and nucleosomal DNA via product and kinetic analysis.Stereochemical control of nucleosome targeting by platinum-intercalator antitumor agents.Rapid Histone-Catalyzed DNA Lesion Excision and Accompanying Protein Modification in Nucleosomes and Nucleosome Core Particles.Mechanistic studies on histone catalyzed cleavage of apyrimidinic/apurinic sites in nucleosome core particlesHistone modification via rapid cleavage of C4'-oxidized abasic sites in nucleosome core particles.Nucleosome core particle-catalyzed strand scission at abasic sites.Abasic and oxidized abasic site reactivity in DNA: enzyme inhibition, cross-linking, and nucleosome catalyzed reactions.Enzymatic excision of uracil residues in nucleosomes depends on the local DNA structure and dynamics.Reversible DNA-Protein Cross-Linking at Epigenetic DNA Marks.Probing Enhanced Double-Strand Break Formation at Abasic Sites within Clustered Lesions in Nucleosome Core Particles.Enhanced Cleavage at Abasic Sites within Clustered Lesions in Nucleosome Core Particles
P2860
Q27310150-8D2D83D1-0A82-412B-84AC-343674601EC3Q27661854-5583E432-39E9-4835-A4E2-19F21EDEA589Q27670649-5DAC9C93-4C68-41A5-87D0-DCE4F29CD651Q27682260-03B4F7B7-9764-4BB6-A36B-7699C546914CQ27704876-1F52B628-95F1-4A3C-A207-F138A6AD8E2DQ33541170-272B24B4-B343-410A-9BE3-344255414507Q34345579-E6241A05-BE98-44EC-8950-002BDC1D4837Q34450293-F156582B-C56D-455B-8B7F-F46E7FEFB51DQ34642470-A4F5799F-DF2D-4E61-BF0C-C7D7B2ECB882Q35108248-71152AB6-726D-4997-B342-511B063236D3Q35770597-2EEA860F-3133-4CA9-8BBF-A8AD3F250F7CQ36181450-30E33A84-7FBC-4DA9-93DC-4CD8F3BAABA8Q36336116-48A0D7A9-B2DC-49FC-8982-2168DCB79834Q36800809-68811D98-F111-4E26-A3B0-6EBAD0966207Q37033853-BDD1029D-4CA4-4941-BF28-B8252F3771E5Q37620930-389E76C2-884D-400B-96AA-77F8C031704CQ42029581-3F9D04B7-67A3-4076-B6DB-1F11C204EF9EQ47817094-31A4FE88-8DAE-413E-9743-B67764A08E93Q48124453-D70A381D-4F5C-4210-887D-2659A368265FQ57025715-B37FACD6-D03A-4843-934C-0123B5D8DE20
P2860
DNA stretching in the nucleosome facilitates alkylation by an intercalating antitumour agent
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
DNA stretching in the nucleoso ...... intercalating antitumour agent
@ast
DNA stretching in the nucleoso ...... intercalating antitumour agent
@en
DNA stretching in the nucleoso ...... intercalating antitumour agent
@nl
type
label
DNA stretching in the nucleoso ...... intercalating antitumour agent
@ast
DNA stretching in the nucleoso ...... intercalating antitumour agent
@en
DNA stretching in the nucleoso ...... intercalating antitumour agent
@nl
prefLabel
DNA stretching in the nucleoso ...... intercalating antitumour agent
@ast
DNA stretching in the nucleoso ...... intercalating antitumour agent
@en
DNA stretching in the nucleoso ...... intercalating antitumour agent
@nl
P2093
P2860
P356
P1476
DNA stretching in the nucleoso ...... intercalating antitumour agent
@en
P2093
Curt A Davey
Gabriela E Davey
Yuancai Dong
P2860
P304
P356
10.1093/NAR/GKP1174
P407
P577
2010-04-01T00:00:00Z