Visualizing the reaction coordinate of an O-GlcNAc hydrolase
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Inhibition of a bacterial O-GlcNAcase homologue by lactone and lactam derivatives: structural, kinetic and thermodynamic analysesStructural and mechanistic insight into N-glycan processing by endo-α-mannosidaseGaining insight into the inhibition of glycoside hydrolase family 20 exo-β-N-acetylhexosaminidases using a structural approachMetabolism of Vertebrate Amino Sugars with N-Glycolyl Groups: INTRACELLULAR -O-LINKED N-GLYCOLYLGLUCOSAMINE (GlcNGc), UDP-GlcNGc, AND THE BIOCHEMICAL AND STRUCTURAL RATIONALE FOR THE SUBSTRATE TOLERANCE OF -O-LINKED -N-ACETYLGLUCOSAMINIDASEThree-dimensional structure of aStreptomyces sviceusGNAT acetyltransferase with similarity to the C-terminal domain of the human GH84O-GlcNAcaseStructure of a complete four-domain chitinase from Moritella marina, a marine psychrophilic bacteriumSelective trihydroxyazepane NagZ inhibitors increase sensitivity of Pseudomonas aeruginosa to β-lactamsGaining insight into the catalysis by GH20 lacto-N-biosidase using small molecule inhibitors and structural analysisO-GlcNAcase: promiscuous hexosaminidase or key regulator of O-GlcNAc signaling?Tail tubular protein A: a dual-function tail protein of Klebsiella pneumoniae bacteriophage KP32.Combining weak affinity chromatography, NMR spectroscopy and molecular simulations in carbohydrate-lysozyme interaction studies.OGA inhibition by GlcNAc-selenazolineDevelopment of inhibitors as research tools for carbohydrate-processing enzymes.O-GlcNAc signalling: implications for cancer cell biology.Dilution of dipolar interactions in a spin-labeled, multimeric metalloenzyme for DEER studies.Chemical approaches to study O-GlcNAcylation.Efficient and Regioselective Synthesis of β-GalNAc/GlcNAc-Lactose by a Bifunctional Transglycosylating β-N-Acetylhexosaminidase from Bifidobacterium bifidum.Nutrient-driven O-GlcNAc cycling - think globally but act locally.Computational enzymatic catalysis--clarifying enzymatic mechanisms with the help of computers.Chemical tools to explore nutrient-driven O-GlcNAc cycling.An allolactose trapped at the lacZ β-galactosidase active site with its galactosyl moiety in a (4)H3 conformation provides insights into the formation, conformation, and stabilization of the transition state.In Vitro Biochemical Assays for O-GlcNAc-Processing Enzymes.Structural and functional insight into human O-GlcNAcaseStructural insights into the substrate binding adaptability and specificity of human O-GlcNAcaseStructures of human O-GlcNAcase and its complexes reveal a new substrate recognition mode.Development of an indicator for the direct visualization of radical intermediates in organic reactions.Structural and mechanistic insights into a Bacteroides vulgatus retaining N-acetyl-β-galactosaminidase that uses neighbouring group participation.Computational evidence for the substrate-assisted catalytic mechanism of O-GlcNAcase. A DFT investigation
P2860
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P2860
Visualizing the reaction coordinate of an O-GlcNAc hydrolase
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Visualizing the reaction coordinate of an O-GlcNAc hydrolase
@ast
Visualizing the reaction coordinate of an O-GlcNAc hydrolase
@en
Visualizing the reaction coordinate of an O-GlcNAc hydrolase
@nl
type
label
Visualizing the reaction coordinate of an O-GlcNAc hydrolase
@ast
Visualizing the reaction coordinate of an O-GlcNAc hydrolase
@en
Visualizing the reaction coordinate of an O-GlcNAc hydrolase
@nl
prefLabel
Visualizing the reaction coordinate of an O-GlcNAc hydrolase
@ast
Visualizing the reaction coordinate of an O-GlcNAc hydrolase
@en
Visualizing the reaction coordinate of an O-GlcNAc hydrolase
@nl
P50
P356
P1476
Visualizing the reaction coordinate of an O-GlcNAc hydrolase
@en
P304
P356
10.1021/JA9086769
P407
P577
2010-02-17T00:00:00Z