Conformational differences between the wild type and V30M mutant transthyretin modulate its binding to genistein: implications to tetramer stability and ligand-binding
about
Potent Kinetic Stabilizers That Prevent Transthyretin-Mediated Cardiomyocyte ProteotoxicityFluorogenic small molecules requiring reaction with a specific protein to create a fluorescent conjugate for biological imaging-what we know and what we need to learnX-ray crystal structure and activity of fluorenyl-based compounds as transthyretin fibrillogenesis inhibitorsStructural evidence for asymmetric ligand binding to transthyretinSynthesis and structural analysis of halogen substituted fibril formation inhibitors of Human Transthyretin (TTR)Applications of isothermal titration calorimetry in pure and applied research--survey of the literature from 2010.Stability of the transthyretin molecule as a key factor in the interaction with a-beta peptide--relevance in Alzheimer's disease.A competition assay to identify amyloidogenesis inhibitors by monitoring the fluorescence emitted by the covalent attachment of a stilbene derivative to transthyretin.Brain endogenous estrogen levels determine responses to estrogen replacement therapy via regulation of BACE1 and NEP in female Alzheimer's transgenic mice.Solid-State NMR Studies Reveal Native-like β-Sheet Structures in Transthyretin Amyloid.Evolution of quantitative methods in protein secondary structure determination via deep-ultraviolet resonance Raman spectroscopy.The transthyretin amyloidoses: from delineating the molecular mechanism of aggregation linked to pathology to a regulatory-agency-approved drug.Application of isothermal titration calorimetry as a tool to study natural product interactions.Transthyretin Binding Heterogeneity and Anti-amyloidogenic Activity of Natural Polyphenols and Their MetabolitesEvaluating the effect of mutations and ligand binding on transthyretin homotetramer dynamics.Discovery of γ-Mangostin as an Amyloidogenesis Inhibitor.Characteristics of human lysozyme and its disease-related mutants in their unfolded states.Factors affecting the physical stability (aggregation) of peptide therapeutics.Lignin-derived oak phenolics: a theoretical examination of additional potential health benefits of red wine.
P2860
Q27671971-97DCDC19-A16C-49BC-B391-854D0811A0C4Q27680199-9DBCA23E-3993-4CF8-89F6-772E116D8656Q27701718-9A167CAC-267D-40A0-8B35-C565C9CD9B0FQ27701741-9EFECD3E-CAC1-4CA1-8C7A-F8B926E26E0CQ27704552-99C1A523-3581-4FF7-B0C7-7B3EDC7124B6Q34244067-7786DA36-77DE-4671-9F79-71E3F135F446Q34428889-ECE67761-7B55-4A33-9854-5C902BD5E0B9Q34576022-3D9D6432-D372-4190-8588-287689265D38Q36650676-8EBC1138-1EC1-42C4-B9D2-96614BBC2608Q37280085-FE1DA665-C1C4-4591-88B7-AF0B771E7FEEQ37965338-CD6947A5-13F6-4847-BDAD-6E983C33F417Q37975816-5E83FAF8-9437-4070-B6A3-533E452C83DAQ38292496-251B0202-48A8-4A66-BE5B-C837152FD2E2Q40430478-1304990E-1E31-49EB-A778-6055030F0930Q41007447-5A9F0854-8E25-46CA-A4A9-8DFEBCCC4535Q43263823-946B90A6-D49B-4C9F-BF52-8347EAE81D52Q45941788-B6D1440D-77C7-4984-AF10-A73B83C72DA3Q46259884-A80FF515-15B1-430F-BDF1-E7107B2C9132Q50554887-9EBA5F0E-E1FF-4AEC-A0D6-3E277F6B49DD
P2860
Conformational differences between the wild type and V30M mutant transthyretin modulate its binding to genistein: implications to tetramer stability and ligand-binding
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年学术文章
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2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
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name
Conformational differences bet ...... r stability and ligand-binding
@ast
Conformational differences bet ...... r stability and ligand-binding
@en
Conformational differences bet ...... r stability and ligand-binding
@nl
type
label
Conformational differences bet ...... r stability and ligand-binding
@ast
Conformational differences bet ...... r stability and ligand-binding
@en
Conformational differences bet ...... r stability and ligand-binding
@nl
prefLabel
Conformational differences bet ...... r stability and ligand-binding
@ast
Conformational differences bet ...... r stability and ligand-binding
@en
Conformational differences bet ...... r stability and ligand-binding
@nl
P2093
P50
P1476
Conformational differences bet ...... r stability and ligand-binding
@en
P2093
Daniela B B Trivella
Helton José Wiggers
Leonardo de Castro Palmieri
Luís Maurício T R Lima
P304
P356
10.1016/J.JSB.2010.03.002
P577
2010-03-06T00:00:00Z