The x-ray crystal structure of the first RNA recognition motif and site-directed mutagenesis suggest a possible HuR redox sensing mechanism

The x-ray crystal structure of the first RNA recognition motif and site-directed mutagenesis suggest a possible HuR redox sensing mechanism

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http://www.wikidata.org/entity/Q27660171
Redox signalling directly regulates TDP-43 via cysteine oxidation and disulphide cross-linkingRedox regulation of FoxO transcription factorsThe structure of the ARE-binding domains of Hu antigen R (HuR) undergoes conformational changes during RNA bindingPreliminary crystallographic analysis of the RNA-binding domain of HuR and its poly(U)-binding properties.Discovering and validating unknown phospho-sites from p38 and HuR protein kinases in vitro by Phosphoproteomic and Bioinformatic toolsThe C-terminal RNA binding motif of HuR is a multi-functional domain leading to HuR oligomerization and binding to U-rich RNA targets.NPGPx modulates CPEB2-controlled HIF-1α RNA translation in response to oxidative stressClinical significance of HuR expression in human malignancy.Changes in cellular mRNA stability, splicing, and polyadenylation through HuR protein sequestration by a cytoplasmic RNA virusHu Antigen R (HuR) multimerization contributes to glioma disease progression.Posttranscriptional regulation of FOXO expression: microRNAs and beyond.Dimerization model of the C-terminal RNA Recognition Motif of HuR.Posttranscriptional Upregulation of IDH1 by HuR Establishes a Powerful Survival Phenotype in Pancreatic Cancer Cells.RNA Binding Protein Regulation and Cross-Talk in the Control of AU-rich mRNA Fate.Regulation of HuR structure and function by dihydrotanshinone-I.
P2860

The x-ray crystal structure of the first RNA recognition motif and site-directed mutagenesis suggest a possible HuR redox sensing mechanism

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http://www.wikidata.org/entity/Q27660171
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2010 nî lūn-bûn
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2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2010 թվականի ապրիլին հրատարակված գիտական հոդված
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2010年の論文
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年學術文章
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name
The x-ray crystal structure of ...... le HuR redox sensing mechanism
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The x-ray crystal structure of ...... le HuR redox sensing mechanism
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The x-ray crystal structure of ...... le HuR redox sensing mechanism
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The x-ray crystal structure of ...... le HuR redox sensing mechanism
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The x-ray crystal structure of ...... le HuR redox sensing mechanism
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The x-ray crystal structure of ...... le HuR redox sensing mechanism
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The x-ray crystal structure of ...... le HuR redox sensing mechanism
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The x-ray crystal structure of ...... le HuR redox sensing mechanism
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The x-ray crystal structure of ...... le HuR redox sensing mechanism
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P1433
P1476
P2093
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P31
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P1433
P1476
The x-ray crystal structure of ...... le HuR redox sensing mechanism
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P2093
P304
P31
P356
P407
P433
P478
P577
P698
P921