Discovery of imidazo[1,5-a]pyrido[3,2-e]pyrazines as a new class of phosphodiesterase 10A inhibitiors

Discovery of imidazo[1,5-a]pyrido[3,2-e]pyrazines as a new class of phosphodiesterase 10A inhibitiors

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http://www.wikidata.org/entity/Q27661409
Advances in targeting cyclic nucleotide phosphodiesterasesSynthesis and in vitro evaluation of new analogues as inhibitors for phosphodiesterase 10A.Radiosynthesis and Radiotracer Properties of a 7-(2-[18F]Fluoroethoxy)-6-methoxypyrrolidinylquinazoline for Imaging of Phosphodiesterase 10A with PET.Phosphodiesterase 10A inhibitors: a 2009 - 2012 patent update.Phosphodiesterase 10A inhibitors: analysis of US/EP patents granted since 2012.Phosphodiesterase-1b deletion confers depression-like behavioral resistance separate from stress-related effects in mice.Computational determination of binding structures and free energies of phosphodiesterase-2 with benzo[1,4]diazepin-2-one derivatives.Effect of PDE10A inhibitors on MK-801-induced immobility in the forced swim test.Composite multi-parameter ranking of real and virtual compounds for design of MC4R agonists: renaissance of the Free-Wilson methodology.Particle swarm optimization and genetic algorithm as feature selection techniques for the QSAR modeling of imidazo[1,5-a]pyrido[3,2-e]pyrazines, inhibitors of phosphodiesterase 10A.Phosphodiesterase-1b (Pde1b) knockout mice are resistant to forced swim and tail suspension induced immobility and show upregulation of Pde10a.TAK-063, a novel PDE10A inhibitor with balanced activation of direct and indirect pathways, provides a unique opportunity for the treatment of schizophrenia.Inhibition of Adrenergic and Non-Adrenergic Smooth Muscle Contraction in the Human Prostate by the Phosphodiesterase 10-Selective Inhibitor TC-E 5005.
P2860

Discovery of imidazo[1,5-a]pyrido[3,2-e]pyrazines as a new class of phosphodiesterase 10A inhibitiors

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http://www.wikidata.org/entity/Q27661409
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2010 nî lūn-bûn
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2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
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2010 թվականի հունիսին հրատարակված գիտական հոդված
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2010年の論文
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2010年論文
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2010年論文
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2010年論文
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2010年論文
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2010年論文
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2010年论文
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name
Discovery of imidazo[1,5-a]pyr ...... sphodiesterase 10A inhibitiors
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Discovery of imidazo[1,5-a]pyr ...... sphodiesterase 10A inhibitiors
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Discovery of imidazo[1,5-a]pyr ...... sphodiesterase 10A inhibitiors
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type
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Discovery of imidazo[1,5-a]pyr ...... sphodiesterase 10A inhibitiors
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Discovery of imidazo[1,5-a]pyr ...... sphodiesterase 10A inhibitiors
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Discovery of imidazo[1,5-a]pyr ...... sphodiesterase 10A inhibitiors
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Discovery of imidazo[1,5-a]pyr ...... sphodiesterase 10A inhibitiors
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Discovery of imidazo[1,5-a]pyr ...... sphodiesterase 10A inhibitiors
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Discovery of imidazo[1,5-a]pyr ...... sphodiesterase 10A inhibitiors
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P2093
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P1476
Discovery of imidazo[1,5-a]pyr ...... sphodiesterase 10A inhibitiors
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P2093
P304
P31
P356
P407
P433
P478
P577
P698