Crystal structures of IL-2-inducible T cell kinase complexed with inhibitors: insights into rational drug design and activity regulation

Crystal structures of IL-2-inducible T cell kinase complexed with inhibitors: insights into rational drug design and activity regulation

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http://www.wikidata.org/entity/Q27662256
Insights into the conformational flexibility of Bruton's tyrosine kinase from multiple ligand complex structuresA Novel Approach to the Discovery of Small-Molecule Ligands of CDK2X-ray crystal structure of bone marrow kinase in the x chromosome: a Tec family kinaseSubstrate and Inhibitor Specificity of the Type II p21-Activated Kinase, PAK6Selectively targeting an inactive conformation of interleukin-2-inducible T-cell kinase by allosteric inhibitorsEmergence of polyclonal FLT3 tyrosine kinase domain mutations during sequential therapy with sorafenib and sunitinib in FLT3-ITD-positive acute myeloid leukemia.Prodrug AST-003 Improves the Therapeutic Index of the Multi-Targeted Tyrosine Kinase Inhibitor SunitinibNanolitre-scale crystallization using acoustic liquid-transfer technology.Discovery of potent inhibitors for interleukin-2-inducible T-cell kinase: structure-based virtual screening and molecular dynamics simulation approaches.Can structural features of kinase receptors provide clues on selectivity and inhibition? A molecular modeling studyBruton's TK inhibitors: structural insights and evolution of clinical candidates.TEC and MAPK Kinase Signalling Pathways in T helper (TH) cell Development, TH2 Differentiation and Allergic Asthma.Advances in the design of ITK inhibitors.Productive induced metastability in allosteric modulation of kinase function.Sunitinib: from charge-density studies to interaction with proteins.
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Crystal structures of IL-2-inducible T cell kinase complexed with inhibitors: insights into rational drug design and activity regulation

Item
http://www.wikidata.org/entity/Q27662256
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2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
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name
Crystal structures of IL-2-ind ...... design and activity regulation
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Crystal structures of IL-2-ind ...... design and activity regulation
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Crystal structures of IL-2-ind ...... design and activity regulation
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type
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Crystal structures of IL-2-ind ...... design and activity regulation
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Crystal structures of IL-2-ind ...... design and activity regulation
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Crystal structures of IL-2-ind ...... design and activity regulation
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prefLabel
Crystal structures of IL-2-ind ...... design and activity regulation
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Crystal structures of IL-2-ind ...... design and activity regulation
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Crystal structures of IL-2-ind ...... design and activity regulation
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Crystal structures of IL-2-ind ...... design and activity regulation
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10.1111/J.1747-0285.2010.00993.X
P433
P478
P50
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P5875
P698
P921