Structure of recombinant human rheumatoid arthritic synovial fluid phospholipase A2 at 2.2 A resolution
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Novel human secreted phospholipase A(2) with homology to the group III bee venom enzymePhospholipase A2 enzymes: physical structure, biological function, disease implication, chemical inhibition, and therapeutic interventionThe crystal structure of prokaryotic phospholipase A2A novel prokaryotic phospholipase A2. Characterization, gene cloning, and solution structureCrystal structure of human group X secreted phospholipase A2. Electrostatically neutral interfacial surface targets zwitterionic membranesCrystal Structure of a Class XIB Phospholipase A2 (PLA2): RICE (ORYZA SATIVA) ISOFORM-2 PLA2 AND AN OCTANOATE COMPLEXSelective Inhibition of Human Group IIA-secreted Phospholipase A2 (hGIIA) Signaling Reveals Arachidonic Acid Metabolism Is Associated with Colocalization of hGIIA to Vimentin in Rheumatoid SynoviocytesSolution structure of porcine pancreatic phospholipase A2Structure-based design of the first potent and selective inhibitor of human non-pancreatic secretory phospholipase A2Crystal structure of phospholipase A2 from Indian cobra reveals a trimeric associationCrystal structure of vipoxin at 2.0 A: an example of regulation of a toxic function generated by molecular evolutionPhospholipase A2: its usefulness in laboratory diagnostics.The electrostatic basis for the interfacial binding of secretory phospholipases A2.Inhibition of secreted phospholipases A₂ by 2-oxoamides based on α-amino acids: Synthesis, in vitro evaluation and molecular docking calculations.Therapeutic application of natural inhibitors against snake venom phospholipase A(2).An inhibitor of phospholipase A2 group IIA modulates adipocyte signaling and protects against diet-induced metabolic syndrome in ratsTotal chemical synthesis of enzymatically active human type II secretory phospholipase A2.Identification of a specific region of low molecular weight phospholipases A2 (residues 21-40) as a potential target for structure-based design of inhibitors of these enzymesGeneration of lyso-phospholipids from surfactant in acute lung injury is mediated by type-II phospholipase A2 and inhibited by a direct surfactant protein A-phospholipase A2 protein interactionEnzymatic toxins from snake venom: structural characterization and mechanism of catalysis.Nonbactericidal secreted phospholipase A2s are potential anti-inflammatory factors in the mammary gland.Receptor-binding capability of pancreatic phospholipase A2 is separable from its enzymatic activity.Phospholipase A2 as a mechanosensor.Sequence specific inhibition of human type II phospholipase A2 enzyme activity by phosphorothioate oligonucleotides.Secreted phospholipase A2 enzymes as therapeutic targets.A review on the strategies for the development and application of new anti-arthritic agents.The binding of amide substrate analogues to phospholipase A2. Studies by 13C-nuclear-magnetic-resonance and infrared spectroscopy.CrystTwiV: a webserver for automated phase extension and refinement in X-ray crystallography.Topology of the substrate-binding site of a Lys49-phospholipase A2 influences Ca2+-independent membrane-damaging activity.Mechanism of inhibition of human nonpancreatic secreted phospholipase A2 by the anti-inflammatory agent BMS-181162.Conserved domains and evolution of secreted phospholipases A(2).Enhanced hydrolysis of phosphatidylcholine by human group II non-pancreatic secreted phospholipase A2 as a result of interfacial activation by specific anions. Potential role of cholesterol sulphate.The role of phospholipase A2 in interleukin-1 alpha-mediated inhibition of mineralization of the osteoid formed by fetal rat calvaria cells in vitro.Crystal structure of the complex of group I PLA2 with a group II-specific peptide Leu-Ala-Ile-Tyr-Ser (LAIYS) at 2.6 A resolution.Molecular dynamics study of phospholipase A2 on a membrane surface.Expression of fully active ammodytoxin A, a potent presynaptically neurotoxic phospholipase A2, in Escherichia coli.pCRP-mCRP Dissociation Mechanisms as Potential Targets for the Development of Small-Molecule Anti-Inflammatory Chemotherapeutics.
P2860
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P2860
Structure of recombinant human rheumatoid arthritic synovial fluid phospholipase A2 at 2.2 A resolution
description
1991 nî lūn-bûn
@nan
1991 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
Structure of recombinant human ...... olipase A2 at 2.2 A resolution
@ast
Structure of recombinant human ...... olipase A2 at 2.2 A resolution
@en
Structure of recombinant human ...... olipase A2 at 2.2 A resolution
@nl
type
label
Structure of recombinant human ...... olipase A2 at 2.2 A resolution
@ast
Structure of recombinant human ...... olipase A2 at 2.2 A resolution
@en
Structure of recombinant human ...... olipase A2 at 2.2 A resolution
@nl
prefLabel
Structure of recombinant human ...... olipase A2 at 2.2 A resolution
@ast
Structure of recombinant human ...... olipase A2 at 2.2 A resolution
@en
Structure of recombinant human ...... olipase A2 at 2.2 A resolution
@nl
P2093
P356
P1433
P1476
Structure of recombinant human ...... olipase A2 at 2.2 A resolution
@en
P2093
D B McClure
D K Clawson
J L Bobbitt
R B Hermann
R M Kramer
R W Schevitz
P2888
P356
10.1038/352079A0
P407
P577
1991-07-04T00:00:00Z
P6179
1023767518