Galectin inhibitory disaccharides promote tumour immunity in a breast cancer model
about
Galectin-1 research in T cell immunity: past, present and futureGalectins in epithelial functionsGalectins and their ligands: negative regulators of anti-tumor immunityIdentification of galectin-1 as a critical factor in function of mouse mesenchymal stromal cell-mediated tumor promotionA major secretory defect of tumour-infiltrating T lymphocytes due to galectin impairing LFA-1-mediated synapse completion.Inhibition mechanism of human galectin-7 by a novel galactose-benzylphosphate inhibitorTaloside inhibitors of galectin-1 and galectin-3Investigation into the feasibility of thioditaloside as a novel scaffold for galectin-3-specific inhibitorsStructural basis of multivalent galactose-based dendrimer recognition by human galectin-7Structural characterization of human galectin-4 C-terminal domain: elucidating the molecular basis for recognition of glycosphingolipids, sulfated saccharides and blood group antigensSymmetric dithiodigalactoside: strategic combination of binding studies and detection of selectivity between a plant toxin and human lectins.Thiodigalactoside inhibits murine cancers by concurrently blocking effects of galectin-1 on immune dysregulation, angiogenesis and protection against oxidative stress.Galectin-1 is overexpressed in CD133+ human lung adenocarcinoma cells and promotes their growth and invasiveness.Proteomic Identification of Target Proteins of Thiodigalactoside in White Adipose Tissue from Diet-Induced Obese Rats.Galectin-1 regulates tissue exit of specific dendritic cell populations.Self-assembled glycopeptide nanofibers as modulators of galectin-1 bioactivity.Dual thio-digalactoside-binding modes of human galectins as the structural basis for the design of potent and selective inhibitors.Engineering galectin-glycan interactions for immunotherapy and immunomodulationGalectin-1 is essential for efficient liver regeneration following hepatectomy.Mechanism of immune evasion in breast cancer.Galectin-1 and immunotherapy for brain cancer.Galectin-1 as a potent target for cancer therapy: role in the tumor microenvironment.Three-dimensional structural aspects of protein-polysaccharide interactions.Various ways to improve whole cancer cell vaccines.Galectin-3 inhibitors: a patent review (2008-present).Structural characterisation of human galectin-4 N-terminal carbohydrate recognition domain in complex with glycerol, lactose, 3'-sulfo-lactose, and 2'-fucosyllactose.Synthesis and biological activity of divalent ligands based on 3-deoxy-4-thiolactose, an isosteric analogue of lactose.Design of a peptidic inhibitor that targets the dimer interface of a prototypic galectin.Galectin-1 inhibitors and their potential therapeutic applications: a patent review.Development of a potent melanoma vaccine capable of stimulating CD8(+) T-cells independently of dendritic cells in a mouse model.Inhibiting galectin-1 reduces murine lung metastasis with increased CD4(+) and CD8 (+) T cells and reduced cancer cell adherence.Metabolic inhibition of galectin-1-binding carbohydrates accentuates antitumor immunity.Synthesis, antimicrobial and cytotoxicity evaluation of new cholesterol congenersImmunochemiluminescent detection of galectin-3 in tumoral tissue from prostate.Targeted inhibition of galectin 1 by thiodigalactoside dramatically reduces body weight gain in diet-induced obese rats.Interstrain differences in chronic hepatitis and tumor development in a murine model of inflammation-mediated hepatocarcinogenesis.Glioma-derived galectin-1 regulates innate and adaptive antitumor immunity.Combined inhibition of autophagy protein 5 and galectin-1 by thiodigalactoside reduces diet-induced obesity through induction of white fat browning.Thiodigalactoside shows antitumour activity by beta-galactoside-binding protein and regulatory T cells inhibition in oral squamous cell carcinoma.Increased plasma levels of galectin-1 in pancreatic cancer: potential use as biomarker
P2860
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P2860
Galectin inhibitory disaccharides promote tumour immunity in a breast cancer model
description
2010 nî lūn-bûn
@nan
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Galectin inhibitory disaccharides promote tumour immunity in a breast cancer model
@ast
Galectin inhibitory disaccharides promote tumour immunity in a breast cancer model
@en
Galectin inhibitory disaccharides promote tumour immunity in a breast cancer model
@nl
type
label
Galectin inhibitory disaccharides promote tumour immunity in a breast cancer model
@ast
Galectin inhibitory disaccharides promote tumour immunity in a breast cancer model
@en
Galectin inhibitory disaccharides promote tumour immunity in a breast cancer model
@nl
prefLabel
Galectin inhibitory disaccharides promote tumour immunity in a breast cancer model
@ast
Galectin inhibitory disaccharides promote tumour immunity in a breast cancer model
@en
Galectin inhibitory disaccharides promote tumour immunity in a breast cancer model
@nl
P2093
P50
P3181
P1433
P1476
Galectin inhibitory disaccharides promote tumour immunity in a breast cancer model
@en
P2093
Elwyn Gabutero
Emily M Sullivan
I Darren Grice
Kimberley A Stannard
Koichi Ito
Pauline Low
Stacy A Scott
P304
P3181
P356
10.1016/J.CANLET.2010.08.005
P407
P577
2010-12-28T00:00:00Z