Potent, Highly Selective, and Orally Bioavailable Gem -Difluorinated Monocationic Inhibitors of Neuronal Nitric Oxide Synthase
about
Improved Synthesis of Chiral Pyrrolidine Inhibitors and Their Binding Properties to Neuronal Nitric Oxide SynthaseCyclopropyl- and methyl-containing inhibitors of neuronal nitric oxide synthaseIntramolecular hydrogen bonding: A potential strategy for more bioavailable inhibitors of neuronal nitric oxide synthaseSelective Monocationic Inhibitors of Neuronal Nitric Oxide Synthase. Binding Mode Insights from Molecular Dynamics SimulationsThe anti-cancer agent SU4312 unexpectedly protects against MPP(+) -induced neurotoxicity via selective and direct inhibition of neuronal NOSIntraprotein electron transfer between the FMN and heme domains in endothelial nitric oxide synthase holoenzyme.Development of nitric oxide synthase inhibitors for neurodegeneration and neuropathic pain.Acid-Facilitated Debenzylation of N-Boc, N-Benzyl Double Protected 2-Aminopyridinomethylpyrrolidine DerivativesRational Design of Orthogonal Multipolar Interactions with Fluorine in Protein-Ligand ComplexesRole of an isoform-specific serine residue in FMN-heme electron transfer in inducible nitric oxide synthase.On the selectivity of neuronal NOS inhibitorsRecent advances toward improving the bioavailability of neuronal nitric oxide synthase inhibitors.The discovery of potentially selective human neuronal nitric oxide synthase (nNOS) Inhibitors: a combination of pharmacophore modelling, CoMFA, virtual screening and molecular docking studies.Palladium-Catalyzed Arylation of Fluoroalkylamines.Structural basis for isoform-selective inhibition in nitric oxide synthase.Improvement of Cell Permeability of Human Neuronal Nitric Oxide Synthase Inhibitors Using Potent and Selective 2-Aminopyridine-Based Scaffolds with a Fluorobenzene Linker.Nonconventional difluoroalkylation of C(sp2)-H bonds through hydroarylation.Insights into the structural determinants for selective inhibition of nitric oxide synthase isoforms
P2860
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P2860
Potent, Highly Selective, and Orally Bioavailable Gem -Difluorinated Monocationic Inhibitors of Neuronal Nitric Oxide Synthase
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Potent, Highly Selective, and ...... Neuronal Nitric Oxide Synthase
@ast
Potent, Highly Selective, and ...... Neuronal Nitric Oxide Synthase
@en
Potent, Highly Selective, and ...... Neuronal Nitric Oxide Synthase
@nl
type
label
Potent, Highly Selective, and ...... Neuronal Nitric Oxide Synthase
@ast
Potent, Highly Selective, and ...... Neuronal Nitric Oxide Synthase
@en
Potent, Highly Selective, and ...... Neuronal Nitric Oxide Synthase
@nl
prefLabel
Potent, Highly Selective, and ...... Neuronal Nitric Oxide Synthase
@ast
Potent, Highly Selective, and ...... Neuronal Nitric Oxide Synthase
@en
Potent, Highly Selective, and ...... Neuronal Nitric Oxide Synthase
@nl
P2093
P2860
P356
P1476
Potent, highly selective, and ...... neuronal nitric oxide synthase
@en
P2093
Fengtian Xue
Huiying Li
Jianguo Fang
Linda J Roman
Richard B Silverman
Silvia L Delker
Thomas L Poulos
P2860
P304
14229-14238
P356
10.1021/JA106175Q
P407
P577
2010-10-01T00:00:00Z