Danthron Functions as a Retinoic X Receptor Antagonist by Stabilizing Tetramers of the Receptor - Wikidata - awgldk - TriplyDB

Danthron Functions as a Retinoic X Receptor Antagonist by Stabilizing Tetramers of the Receptor

Danthron Functions as a Retinoic X Receptor Antagonist by Stabilizing Tetramers of the Receptor

http://www.wikidata.org/entity/Q27665948

about

The retinoid X receptors and their ligands Regulation of the nongenomic actions of retinoid X receptor-α by targeting the coregulator-binding sites Structural Basis for Retinoic X Receptor Repression on the Tetramer Advances in drug design with RXR modulators RXR Partial Agonist CBt-PMN Exerts Therapeutic Effects on Type 2 Diabetes without the Side Effects of RXR Full Agonists.Danthron triggers ROS and mitochondria-mediated apoptotic death in C6 rat glioma cells through caspase cascades, apoptosis-inducing factor and endonuclease G multiple signaling.NSC-640358 acts as RXRα ligand to promote TNFα-mediated apoptosis of cancer cell Targeting truncated RXRα for cancer therapy.Synthesis and SAR study of modulators inhibiting tRXRα-dependent AKT activation.Danthron activates AMP-activated protein kinase and regulates lipid and glucose metabolism in vitro.Retinoid X receptor ligands: a patent review (2007 - 2013).Application of isothermal titration calorimetry as a tool to study natural product interactions.Latanoprost effectively ameliorates glucose and lipid disorders in db/db and ob/ob mice.Quantitative toxicoproteomic analysis of zebrafish embryos exposed to a retinoid X receptor antagonist UVI3003.Modulation of nongenomic activation of PI3K signalling by tetramerization of N-terminally-cleaved RXRα.A representative retinoid X receptor antagonist UVI3003 induced teratogenesis in zebrafish embryos.Natural product modulators of human sensations and mood: molecular mechanisms and therapeutic potential.Antagonist-perturbation mechanism for activation function-2 fixed motifs: active conformation and docking mode of retinoid X receptor antagonists.Identification of danthron as an isoform-specific inhibitor of HEME OXYGENASE-1/cytochrome P450 reductase interaction with anti-tumor activity.Retinoid X Receptor Antagonists Overview of the structure-based non-genomic effects of the nuclear receptor RXRα

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Danthron Functions as a Retinoic X Receptor Antagonist by Stabilizing Tetramers of the Receptor

http://www.wikidata.org/entity/Q27665948

description

2011 nî lūn-bûn

@nan

2011 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2011 թվականի հունվարին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Danthron Functions as a Retino ...... zing Tetramers of the Receptor

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Danthron Functions as a Retino ...... zing Tetramers of the Receptor

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Danthron Functions as a Retino ...... zing Tetramers of the Receptor

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Danthron Functions as a Retino ...... zing Tetramers of the Receptor

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Danthron Functions as a Retino ...... zing Tetramers of the Receptor

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JBC.M110.166215

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Journal of Biological Chemistry

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Danthron Functions as a Retino ...... zing Tetramers of the Receptor

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Chenjing Li

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Haitao Zhang

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Hong Ding

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Hualiang Jiang

http://www.w3.org/2001/XMLSchema#string

Jing Chen

http://www.w3.org/2001/XMLSchema#string

Li Li

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Liang Yu

http://www.w3.org/2001/XMLSchema#string

Lihong Hu

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Lili Chen

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Rong Zhou

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P2860

Crystal structure of the human RXRalpha ligand-binding domain bound to its natural ligand: 9-cis retinoic acid

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

PROCHECK: a program to check the stereochemical quality of protein structures

Processing of X-ray diffraction data collected in oscillation mode

Crystal structure of a heterodimeric complex of RAR and RXR ligand-binding domains

Structural basis for autorepression of retinoid X receptor by tetramer formation and the AF-2 helix

Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARalpha

Molecular recognition of agonist ligands by RXRs

Modulators of the structural dynamics of the retinoid X receptor to reveal receptor function

Structural basis for catalytic and inhibitory mechanisms of beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ)

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1868-75

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scholarly article

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