The mechanism of sodium and substrate release from the binding pocket of vSGLT - Wikidata - awgldk - TriplyDB

The mechanism of sodium and substrate release from the binding pocket of vSGLT

The mechanism of sodium and substrate release from the binding pocket of vSGLT

http://www.wikidata.org/entity/Q27666183

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Visualizing functional motions of membrane transporters with molecular dynamics simulations How LeuT shapes our understanding of the mechanisms of sodium-coupled neurotransmitter transporters Complete mapping of substrate translocation highlights the role of LeuT N-terminal segment in regulating transport cycle Substrate-bound outward-open state of the betaine transporter BetP provides insights into Na+ coupling.Unveiling the Mechanism of Arginine Transport through AdiC with Molecular Dynamics Simulations: The Guiding Role of Aromatic Residues Substrate specificity and ion coupling in the Na+/betaine symporter BetP Insights into transport mechanism from LeuT engineered to transport tryptophan X-ray structures of LeuT in substrate-free outward-open and apo inward-open states Structure and mechanism of a glutamate-GABA antiporter Arginine oscillation explains Na+ independence in the substrate/product antiporter CaiT Alternating-access mechanism in conformationally asymmetric trimers of the betaine transporter BetP Sugar binding residue affects apparent Na+ affinity and transport stoichiometry in mouse sodium/glucose cotransporter type 3B Conformational Changes in Two Inter-Helical Loops of Mhp1 Membrane Transporter.A gate-free pathway for substrate release from the inward-facing state of the Na⁺-galactose transporter Simulated annealing reveals the kinetic activity of SGLT1, a member of the LeuT structural family.Modelling and mutational analysis of Aspergillus nidulans UreA, a member of the subfamily of urea/H⁺ transporters in fungi and plants A mechanism for intracellular release of Na+ by neurotransmitter/sodium symporters.Conformational dynamics of ligand-dependent alternating access in LeuT.Structural insights into the elevator-like mechanism of the sodium/citrate symporter CitS.NBCe1 as a model carrier for understanding the structure-function properties of Na⁺ -coupled SLC4 transporters in health and disease.Identification of a mutation associated with fatal Foal Immunodeficiency Syndrome in the Fell and Dales pony.Forces and dynamics of glucose and inhibitor binding to sodium glucose co-transporter SGLT1 studied by single molecule force spectroscopy.Conserved tyrosine in the first transmembrane segment of solute:sodium symporters is involved in Na+-coupled substrate co-transport.Evolutionary relationship between 5+5 and 7+7 inverted repeat folds within the amino acid-polyamine-organocation superfamily.Conformational cycle and ion-coupling mechanism of the Na+/hydantoin transporter Mhp1.Computational and biochemical docking of the irreversible cocaine analog RTI 82 directly demonstrates ligand positioning in the dopamine transporter central substrate-binding site.High selectivity of the γ-aminobutyric acid transporter 2 (GAT-2, SLC6A13) revealed by structure-based approach.Mechanism of melibiose/cation symport of the melibiose permease of Salmonella typhimurium.Metadynamics simulations reveal a Na+ independent exiting path of galactose for the inward-facing conformation of vSGLT Identification of a second substrate-binding site in solute-sodium symporters.The molecular mechanism of ion-dependent gating in secondary transporters.A conserved asparagine residue in transmembrane segment 1 (TM1) of serotonin transporter dictates chloride-coupled neurotransmitter transport Interaction of H+ with the extracellular and intracellular aspects of hMATE1.Properties of an inward-facing state of LeuT: conformational stability and substrate release.Importance of host cell arginine uptake in Francisella phagosomal escape and ribosomal protein amounts.The structural pathway for water permeation through sodium-glucose cotransporters Simulations of the alternating access mechanism of the sodium symporter Mhp1.Interaction of α-Lipoic Acid with the Human Na+/Multivitamin Transporter (hSMVT).Bridging the gap between structure and kinetics of human SGLT1.The Human Sodium-Glucose Cotransporter (hSGLT1) Is a Disulfide-Bridged Homodimer with a Re-Entrant C-Terminal Loop

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P2860

The mechanism of sodium and substrate release from the binding pocket of vSGLT

http://www.wikidata.org/entity/Q27666183

description

2010 nî lūn-bûn

@nan

2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

The mechanism of sodium and substrate release from the binding pocket of vSGLT

@ast

The mechanism of sodium and substrate release from the binding pocket of vSGLT

@en

The mechanism of sodium and substrate release from the binding pocket of vSGLT

@nl

type

label

The mechanism of sodium and substrate release from the binding pocket of vSGLT

@ast

The mechanism of sodium and substrate release from the binding pocket of vSGLT

@en

The mechanism of sodium and substrate release from the binding pocket of vSGLT

@nl

prefLabel

The mechanism of sodium and substrate release from the binding pocket of vSGLT

@ast

The mechanism of sodium and substrate release from the binding pocket of vSGLT

@en

The mechanism of sodium and substrate release from the binding pocket of vSGLT

@nl

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The mechanism of sodium and substrate release from the binding pocket of vSGLT

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Akira Watanabe

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Ernest M Wright

http://www.w3.org/2001/XMLSchema#string

Jeff Abramson

http://www.w3.org/2001/XMLSchema#string

John M Rosenberg

http://www.w3.org/2001/XMLSchema#string

Michael Grabe

http://www.w3.org/2001/XMLSchema#string

Seungho Choe

http://www.w3.org/2001/XMLSchema#string

P2860

LeuT-desipramine structure reveals how antidepressants block neurotransmitter reuptake

High-resolution structure prediction and the crystallographic phase problem

Positioning of proteins in membranes: a computational approach

Structure of a prokaryotic virtual proton pump at 3.2 Å resolution

The Crystal Structure of a Sodium Galactose Transporter Reveals Mechanistic Insights into Na+/Sugar Symport

Structure and Molecular Mechanism of a Nucleobase-Cation-Symport-1 Family Transporter

A competitive inhibitor traps LeuT in an open-to-out conformation.

Molecular basis of transport and regulation in the Na(+)/betaine symporter BetP

Structure and mechanism of an amino acid antiporter

Structure and Mechanism of a Na+-Independent Amino Acid Transporter

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988-991

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scholarly article

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1907435

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10.1038/NATURE09580

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7326

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468

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Vincent Chaptal

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2010-12-05T00:00:00Z

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49658656

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1032394298

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21131949

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3736980

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