Cryo-EM structure of the E. coli translating ribosome in complex with SRP and its receptor
about
A tale of two GTPases in cotranslational protein targetingStructures of the E. coli translating ribosome with SRP and its receptor and with the translocon.The Crystal Structure of the Signal Recognition Particle in Complex with Its ReceptorStructural basis of signal sequence surveillance and selection by the SRP–FtsY complexThe Structural Basis of FtsY Recruitment and GTPase Activation by SRP RNADirect visualization reveals dynamics of a transient intermediate during protein assembly.Activated GTPase movement on an RNA scaffold drives co-translational protein targetingStructure of the quaternary complex between SRP, SR, and translocon bound to the translating ribosome.Signal recognition particle-ribosome binding is sensitive to nascent chain length.Allosteric response and substrate sensitivity in peptide binding of the signal recognition particle.Molecular mechanism of co-translational protein targeting by the signal recognition particleBirth, life and death of nascent polypeptide chains.Ribosome-SRP-FtsY cotranslational targeting complex in the closed stateRegulation by a chaperone improves substrate selectivity during cotranslational protein targetingFingerloop activates cargo delivery and unloading during cotranslational protein targetingLinkers in the structural biology of protein-protein interactionsMembrane protein insertion and proton-motive-force-dependent secretion through the bacterial holo-translocon SecYEG-SecDF-YajC-YidC.Cryo-electron microscopy of ribosomal complexes in cotranslational folding, targeting, and translocation.Signal recognition particle: an essential protein-targeting machine.Co-translational protein targeting to the bacterial membrane.Fidelity of cotranslational protein targeting by the signal recognition particle.ATPase and GTPase Tangos Drive Intracellular Protein Transport.SecA-a New Twist in the Tale.The C-terminal regions of YidC from Rhodopirellula baltica and Oceanicaulis alexandrii bind to ribosomes and partially substitute for SRP receptor function in Escherichia coli.Membrane protein insertion and assembly by the bacterial holo-translocon SecYEG-SecDF-YajC-YidC.Signal sequence-independent SRP-SR complex formation at the membrane suggests an alternative targeting pathway within the SRP cycle.Analyzing Single-Molecule Protein Transportation Experiments via Hierarchical Hidden Markov Models.Synergistic actions between the SRP RNA and translating ribosome allow efficient delivery of the correct cargos during cotranslational protein targeting.Co-evolution of Two GTPases Enables Efficient Protein Targeting in an RNA-less Chloroplast Signal Recognition Particle Pathway.SecA mediates cotranslational targeting and translocation of an inner membrane protein.Electrostatic Interactions in Protein Structure, Folding, Binding, and Condensation.SIMIBI twins in protein targeting and localization.Dynamic switch of the signal recognition particle from scanning to targeting.Network models reveal stability and structural rearrangement of signal recognition particle.Cotranslational protein targeting to the membrane: Nascent-chain transfer in a quaternary complex formed at the translocon.
P2860
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P2860
Cryo-EM structure of the E. coli translating ribosome in complex with SRP and its receptor
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Cryo-EM structure of the E. co ...... plex with SRP and its receptor
@ast
Cryo-EM structure of the E. co ...... plex with SRP and its receptor
@en
Cryo-EM structure of the E. co ...... plex with SRP and its receptor
@nl
type
label
Cryo-EM structure of the E. co ...... plex with SRP and its receptor
@ast
Cryo-EM structure of the E. co ...... plex with SRP and its receptor
@en
Cryo-EM structure of the E. co ...... plex with SRP and its receptor
@nl
prefLabel
Cryo-EM structure of the E. co ...... plex with SRP and its receptor
@ast
Cryo-EM structure of the E. co ...... plex with SRP and its receptor
@en
Cryo-EM structure of the E. co ...... plex with SRP and its receptor
@nl
P2860
P50
P921
P3181
P356
P1476
Cryo-EM structure of the E. co ...... plex with SRP and its receptor
@en
P2093
Daniel Boehringer
Shu-Ou Shan
P2860
P2888
P3181
P356
10.1038/NSMB.1952
P577
2011-01-01T00:00:00Z
P5875
P6179
1051900408