Crystal structure of a soluble form of human monoglyceride lipase in complex with an inhibitor at 1.35 Å resolution - Wikidata - awgldk - TriplyDB

Crystal structure of a soluble form of human monoglyceride lipase in complex with an inhibitor at 1.35 Å resolution

Crystal structure of a soluble form of human monoglyceride lipase in complex with an inhibitor at 1.35 Å resolution

http://www.wikidata.org/entity/Q27666922

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The Metagenome-Derived Enzymes LipS and LipT Increase the Diversity of Known Lipases The structure of monoacylglycerol lipase from Bacillus sp. H257 reveals unexpected conservation of the cap architecture between bacterial and human enzymes Conformational Plasticity and Ligand Binding of Bacterial Monoacylglycerol Lipase Substrate selectivity of bacterial monoacylglycerol lipase based on crystal structure Structure of the type VI secretion phospholipase effector Tle1 provides insight into its hydrolysis and membrane targeting 2012 Division of medicinal chemistry award address. Trekking the cannabinoid road: a personal perspective Peroxide-Dependent MGL Sulfenylation Regulates 2-AG-Mediated Endocannabinoid Signaling in Brain Neurons Endocannabinoid enzyme engineering: soluble human thio-monoacylglycerol lipase (sol-S-hMGL).Structure of a CGI-58 motif provides the molecular basis of lipid droplet anchoring Specific Inter-residue Interactions as Determinants of Human Monoacylglycerol Lipase Catalytic Competency: A ROLE FOR GLOBAL CONFORMATIONAL CHANGES.Membrane phospholipid bilayer as a determinant of monoacylglycerol lipase kinetic profile and conformational repertoire.Active-site inhibitors modulate the dynamic properties of human monoacylglycerol lipase: a hydrogen exchange mass spectrometry study Crystal Structure of StnA for the Biosynthesis of Antitumor Drug Streptonigrin Reveals a Unique Substrate Binding Mode.The Lid Domain in Lipases: Structural and Functional Determinant of Enzymatic Properties.Monoglyceride lipase: Structure and inhibitors.Monoglyceride lipase as a drug target: At the crossroads of arachidonic acid metabolism and endocannabinoid signaling.Purification, crystallization and preliminary X-ray diffraction analysis of a soluble variant of the monoglyceride lipase Yju3p from the yeast Saccharomyces cerevisiae.Free-energy studies reveal a possible mechanism for oxidation-dependent inhibition of MGL.3D-QSAR study of benzotriazol-1-yl carboxamide scaffold as monoacylglycerol lipase inhibitors.A stereospecific carboxyl esterase from Bacillus coagulans hosting nonlipase activity within a lipase-like fold.Effects of Distal Mutations on the Structure, Dynamics and Catalysis of Human Monoacylglycerol Lipase.A patent review of Monoacylglycerol Lipase (MAGL) inhibitors (2013-2017).Conformational transition pathway in the inhibitor binding process of human monoacylglycerol lipase.In Vitro and in Vivo Evaluation of 11C-Labeled Azetidinecarboxylates for Imaging Monoacylglycerol Lipase by PET Imaging Studies.The crystal structure of monoacylglycerol lipase from M. tuberculosis reveals the basis for specific inhibition.

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P2860

Crystal structure of a soluble form of human monoglyceride lipase in complex with an inhibitor at 1.35 Å resolution

http://www.wikidata.org/entity/Q27666922

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2011 nî lūn-bûn

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2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2011年の論文

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2011年论文

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Crystal structure of a soluble ...... inhibitor at 1.35 Å resolution

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Crystal structure of a soluble ...... inhibitor at 1.35 Å resolution

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Crystal structure of a soluble ...... inhibitor at 1.35 Å resolution

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Crystal structure of a soluble ...... inhibitor at 1.35 Å resolution

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Crystal structure of a soluble ...... inhibitor at 1.35 Å resolution

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Crystal structure of a soluble ...... inhibitor at 1.35 Å resolution

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Crystal structure of a soluble ...... inhibitor at 1.35 Å resolution

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Crystal structure of a soluble ...... inhibitor at 1.35 Å resolution

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Crystal structure of a soluble ...... inhibitor at 1.35 Å resolution

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Crystal structure of a soluble ...... inhibitor at 1.35 Å resolution

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Bruce Grasberger

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Carsten Schubert

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Christopher M Flores

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Céline Schalk-Hihi

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Diane Maguire

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Frank Lewandowski

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Hongchang Ma

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Ingrid Deckman

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James K Kranz

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P2860

Expression of central and peripheral cannabinoid receptors in human immune tissues and leukocyte subpopulations

Crystal structure of the human monoacylglycerol lipase, a key actor in endocannabinoid signaling

Brain monoglyceride lipase participating in endocannabinoid inactivation

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

Electrostatics of nanosystems: application to microtubules and the ribosome

A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

Basic local alignment search tool

Protein crystallization by rational mutagenesis of surface residues: Lys to Ala mutations promote crystallization of RhoGDI

The impact of Glu-->Ala and Glu-->Asp mutations on the crystallization properties of RhoGDI: the structure of RhoGDI at 1.3 A resolution

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670-83

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10.1002/PRO.596

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4

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20

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Charles F Reynolds

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49824499

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21308848

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crystal structure

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