Mechanism underlying selective regulation of G protein-gated inwardly rectifying potassium channels by the psychostimulant-sensitive sorting nexin 27
about
Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteinsA global analysis of SNX27-retromer assembly and cargo specificity reveals a function in glucose and metal ion transportRole of the Retromer Complex in Neurodegenerative DiseasesVirogenetic and optogenetic mechanisms to define potential therapeutic targets in psychiatric disordersPhosphoinositide binding by the SNX27 FERM domain regulates its localization at the immune synapse of activated T-cells.Ligand-Induced Dynamic Changes in Extended PDZ Domains from NHERF1A molecular code for endosomal recycling of phosphorylated cargos by the SNX27-retromer complexGIRK2 splice variants and neuronal G protein-gated K+ channels: implications for channel function and behaviorNeurobiology of resilienceSorting nexin 27 regulation of G protein-gated inwardly rectifying K⁺ channels attenuates in vivo cocaine response.A unique PDZ domain and arrestin-like fold interaction reveals mechanistic details of endocytic recycling by SNX27-retromer.Tethered protein display identifies a novel Kir3.2 (GIRK2) regulator from protein scaffold librariesSNX16 negatively regulates the migration and tumorigenesis of MCF-7 cellsRas-association domain of sorting Nexin 27 is critical for regulating expression of GIRK potassium channelsSorting nexin 27 regulates Aβ production through modulating γ-secretase activity.Snx14 regulates neuronal excitability, promotes synaptic transmission, and is imprinted in the brain of mice.The role of the retromer complex in aging-related neurodegeneration: a molecular and genomic review.GIRK3 gates activation of the mesolimbic dopaminergic pathway by ethanol.Sorting nexin 27 interacts with Fzd7 and mediates Wnt signalling.Sorting nexin 27 couples PTHR trafficking to retromer for signal regulation in osteoblasts during bone growth.Actin-Sorting Nexin 27 (SNX27)-Retromer Complex Mediates Rapid Parathyroid Hormone Receptor Recycling.A defect in the retromer accessory protein, SNX27, manifests by infantile myoclonic epilepsy and neurodegeneration.Atypical parkinsonism-associated retromer mutant alters endosomal sorting of specific cargo proteins.SNX27 Deletion Causes Hydrocephalus by Impairing Ependymal Cell Differentiation and CiliogenesisLoss of sorting nexin 27 contributes to excitatory synaptic dysfunction by modulating glutamate receptor recycling in Down's syndrome.Firing modes of dopamine neurons drive bidirectional GIRK channel plasticity.Insights into the PX (phox-homology) domain and SNX (sorting nexin) protein families: structures, functions and roles in disease.Sorting nexins provide diversity for retromer-dependent trafficking events.Plasticity of PDZ domains in ligand recognition and signaling.The emerging contribution of sequence context to the specificity of protein interactions mediated by PDZ domains.Structures and target recognition modes of PDZ domains: recurring themes and emerging pictures.New insights into the therapeutic potential of Girk channels.G Protein-Gated Potassium Channels: A Link to Drug Addiction.GPCR Signaling and Trafficking: The Long and Short of It.Barcoding of GPCR trafficking and signaling through the various trafficking roadmaps by compartmentalized signaling networks.Expression of sorting nexin 12 is regulated in developing cerebral cortical neurons.SNX27, a protein involved in down syndrome, regulates GPR17 trafficking and oligodendrocyte differentiation.PX-FERM proteins: A link between endosomal trafficking and signaling?β1-adrenergic receptor recycles via a membranous organelle, recycling endosome, by binding with sorting nexin27.GGA1 regulates signal-dependent sorting of BACE1 to recycling endosomes, which moderates Aβ production.
P2860
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P2860
Mechanism underlying selective regulation of G protein-gated inwardly rectifying potassium channels by the psychostimulant-sensitive sorting nexin 27
description
2011 nî lūn-bûn
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2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年论文
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name
Mechanism underlying selective ...... ant-sensitive sorting nexin 27
@ast
Mechanism underlying selective ...... ant-sensitive sorting nexin 27
@en
Mechanism underlying selective ...... ant-sensitive sorting nexin 27
@nl
type
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Mechanism underlying selective ...... ant-sensitive sorting nexin 27
@ast
Mechanism underlying selective ...... ant-sensitive sorting nexin 27
@en
Mechanism underlying selective ...... ant-sensitive sorting nexin 27
@nl
prefLabel
Mechanism underlying selective ...... ant-sensitive sorting nexin 27
@ast
Mechanism underlying selective ...... ant-sensitive sorting nexin 27
@en
Mechanism underlying selective ...... ant-sensitive sorting nexin 27
@nl
P2093
P2860
P3181
P356
P1476
Mechanism underlying selective ...... ant-sensitive sorting nexin 27
@en
P2093
Bartosz Balana
Innokentiy Maslennikov
Kalyn M Stern
Laia Bahima
Paul A Slesinger
Senyon Choe
Witek Kwiatkowski
P2860
P304
P3181
P356
10.1073/PNAS.1018645108
P407
P577
2011-04-05T00:00:00Z