Molecular Mechanism of the Negative Regulation of Smad1/5 Protein by Carboxyl Terminus of Hsc70-interacting Protein (CHIP)
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Fine-tuning multiprotein complexes using small moleculesKey role for ubiquitin protein modification in TGFβ signal transductionTGF-β and BMP signaling in osteoblast differentiation and bone formationA Structural Model of the Sgt2 Protein and Its Interactions with Chaperones and the Get4/Get5 ComplexOncogenic herpesvirus KSHV Hijacks BMP-Smad1-Id signaling to promote tumorigenesisIn vitro characterization of six STUB1 variants in spinocerebellar ataxia 16 reveals altered structural properties for the encoded CHIP proteins.Protein-Protein Interactions Modulate the Docking-Dependent E3-Ubiquitin Ligase Activity of Carboxy-Terminus of Hsc70-Interacting Protein (CHIP)STUB1 mutations in autosomal recessive ataxias - evidence for mutation-specific clinical heterogeneity.A bipartite interaction between Hsp70 and CHIP regulates ubiquitination of chaperoned client proteinsIdentification of C-terminal Hsp70-interacting protein as a mediator of tumour necrosis factor action in osteoblast differentiation by targeting osterix for degradationPrognostic value of the ubiquitin ligase carboxyl terminus of the Hsc70-interacting protein in postmenopausal breast cancer.Recognition of enzymes lacking bound cofactor by protein quality control.The molecular chaperone Hsp70 activates protein phosphatase 5 (PP5) by binding the tetratricopeptide repeat (TPR) domain.Transcriptional factors smad1 and smad9 act redundantly to mediate zebrafish ventral specification downstream of smad5.Hsp70 protein complexes as drug targets.The role of the cytosolic HSP70 chaperone system in diseases caused by misfolding and aberrant trafficking of ion channelsThe remarkable multivalency of the Hsp70 chaperones.Ca2+/S100 proteins act as upstream regulators of the chaperone-associated ubiquitin ligase CHIP (C terminus of Hsc70-interacting protein)STUB1 is essential for T-cell activation by ubiquitinating CARMA1.Ubc13 and COOH terminus of Hsp70-interacting protein (CHIP) are required for growth hormone receptor endocytosis.A novel function of cIAP1 as a mediator of CHIP-driven eIF4E regulation.Specific Binding of Tetratricopeptide Repeat Proteins to Heat Shock Protein 70 (Hsp70) and Heat Shock Protein 90 (Hsp90) Is Regulated by Affinity and Phosphorylation.Heat shock cognate 71 (HSC71) regulates cellular antiviral response by impairing formation of VISA aggregates.Structure and Interactions of the TPR Domain of Sgt2 with Yeast Chaperones and Ybr137wp.The E3 ubiquitin ligase CHIP and the molecular chaperone Hsc70 form a dynamic, tethered complex.CHIP as a membrane-shuttling proteostasis sensor.Combined x-ray crystallography and computational modeling approach to investigate the Hsp90 C-terminal peptide binding to FKBP51.Ubiquitination in Scleroderma Fibrosis and Its Treatment
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P2860
Molecular Mechanism of the Negative Regulation of Smad1/5 Protein by Carboxyl Terminus of Hsc70-interacting Protein (CHIP)
description
2011 nî lūn-bûn
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2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Molecular Mechanism of the Neg ...... c70-interacting Protein (CHIP)
@ast
Molecular Mechanism of the Neg ...... c70-interacting Protein (CHIP)
@en
Molecular Mechanism of the Neg ...... c70-interacting Protein (CHIP)
@nl
type
label
Molecular Mechanism of the Neg ...... c70-interacting Protein (CHIP)
@ast
Molecular Mechanism of the Neg ...... c70-interacting Protein (CHIP)
@en
Molecular Mechanism of the Neg ...... c70-interacting Protein (CHIP)
@nl
prefLabel
Molecular Mechanism of the Neg ...... c70-interacting Protein (CHIP)
@ast
Molecular Mechanism of the Neg ...... c70-interacting Protein (CHIP)
@en
Molecular Mechanism of the Neg ...... c70-interacting Protein (CHIP)
@nl
P2093
P2860
P3181
P356
P1476
Molecular Mechanism of the Neg ...... c70-interacting Protein (CHIP)
@en
P2093
Hong-Rui Wang
Jia-Wei Wu
Yi-Tong Liu
Zhi-Xin Wang
Zhijie Chang
P2860
P304
P3181
P356
10.1074/JBC.M110.201814
P407
P577
2011-05-06T00:00:00Z