The Crystal Structure of the Leishmania major Deoxyuridine Triphosphate Nucleotidohydrolase in Complex with Nucleotide Analogues, dUMP, and Deoxyuridine

The Crystal Structure of the Leishmania major Deoxyuridine Triphosphate Nucleotidohydrolase in Complex with Nucleotide Analogues, dUMP, and Deoxyuridine

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http://www.wikidata.org/entity/Q27667393
Recent developments in drug discovery for leishmaniasis and human African trypanosomiasisOn the catalytic mechanism of dimeric dUTPasesDeinococcus radiodurans DR2231 is a two-metal-ion mechanism hydrolase with exclusive activity on dUTPThe Potential of Secondary Metabolites from Plants as Drugs or Leads against Protozoan Neglected Diseases-Part III: In-Silico Molecular Docking InvestigationsEssential multimeric enzymes in kinetoplastid parasites: A host of potentially druggable protein-protein interactions.In silico work flow for scaffold hopping in LeishmaniaThe Type 2 dUTPase of Bacteriophage ϕNM1 Initiates Mobilization of Staphylococcus aureus Bovine Pathogenicity Island 1.Preventive DNA repair by sanitizing the cellular (deoxy)nucleoside triphosphate pool.In-silico Leishmania target selectivity of antiparasitic terpenoids.Interactions of antiparasitic alkaloids with Leishmania protein targets: a molecular docking analysis.Pyrimidine metabolism in schistosomes: A comparison with other parasites and the search for potential chemotherapeutic targets.Convergent evolution involving dimeric and trimeric dUTPases in pathogenicity island mobilization.Derepression of SaPIbov1 Is Independent of φNM1 Type 2 dUTPase Activity and Is Inhibited by dUTP and dUMP.Fresh insights into the pyrimidine metabolism in the trypanosomatids.Potential steps in the evolution of a fused trimeric all-β dUTPase involve a catalytically competent fused dimeric intermediate.Cysteine residues contribute to the dimerization and enzymatic activity of human nuclear dUTP nucleotidohydrolase (nDut)
P2860

The Crystal Structure of the Leishmania major Deoxyuridine Triphosphate Nucleotidohydrolase in Complex with Nucleotide Analogues, dUMP, and Deoxyuridine

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http://www.wikidata.org/entity/Q27667393
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2011 nî lūn-bûn
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2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2011 թվականի մայիսին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年论文
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name
The Crystal Structure of the L ...... logues, dUMP, and Deoxyuridine
@ast
The Crystal Structure of the L ...... logues, dUMP, and Deoxyuridine
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The Crystal Structure of the L ...... logues, dUMP, and Deoxyuridine
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type
label
The Crystal Structure of the L ...... logues, dUMP, and Deoxyuridine
@ast
The Crystal Structure of the L ...... logues, dUMP, and Deoxyuridine
@en
The Crystal Structure of the L ...... logues, dUMP, and Deoxyuridine
@nl
prefLabel
The Crystal Structure of the L ...... logues, dUMP, and Deoxyuridine
@ast
The Crystal Structure of the L ...... logues, dUMP, and Deoxyuridine
@en
The Crystal Structure of the L ...... logues, dUMP, and Deoxyuridine
@nl
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P1476
P2093
P2860
P304
P31
P356
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P433
P478
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P698
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P932
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P1433
P1476
The crystal structure of the L ...... logues, dUMP, and deoxyuridine
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P932
P953