Phox homology band 4.1/ezrin/radixin/moesin-like proteins function as molecular scaffolds that interact with cargo receptors and Ras GTPases
about
Gephyrin, the enigmatic organizer at GABAergic synapsesMelanoma: from melanocyte to genetic alterations and clinical optionsStructural basis for different phosphoinositide specificities of the PX domains of sorting nexins regulating G-protein signalingStructural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteinsA global analysis of SNX27-retromer assembly and cargo specificity reveals a function in glucose and metal ion transportA landscape of driver mutations in melanomaRole of the Retromer Complex in Neurodegenerative DiseasesPathways and therapeutic targets in melanomaPhosphoinositide binding by the SNX27 FERM domain regulates its localization at the immune synapse of activated T-cells.The Structure of the Ternary Complex of Krev Interaction Trapped 1 (KRIT1) Bound to Both the Rap1 GTPase and the Heart of Glass (HEG1) Cytoplasmic TailStructural Basis for Small G Protein Effector Interaction of Ras-related Protein 1 (Rap1) and Adaptor Protein Krev Interaction Trapped 1 (KRIT1)Structural Determinants for Binding of Sorting Nexin 17 (SNX17) to the Cytoplasmic Adaptor Protein Krev Interaction Trapped 1 (KRIT1)Structure of human SNX10 reveals insights into its role in human autosomal recessive osteopetrosisA molecular code for endosomal recycling of phosphorylated cargos by the SNX27-retromer complexRetromer-mediated endosomal protein sorting: all WASHed up!Structure and Membrane Binding Properties of the Endosomal Tetratricopeptide Repeat (TPR) Domain-containing Sorting Nexins SNX20 and SNX21SNX31: a novel sorting nexin associated with the uroplakin-degrading multivesicular bodies in terminally differentiated urothelial cellsCCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDLA role for sorting nexin 27 in AMPA receptor trafficking.Sorting nexin 27 regulation of G protein-gated inwardly rectifying K⁺ channels attenuates in vivo cocaine response.A unique PDZ domain and arrestin-like fold interaction reveals mechanistic details of endocytic recycling by SNX27-retromer.Cargo recognition in clathrin-mediated endocytosisSNX16 negatively regulates the migration and tumorigenesis of MCF-7 cellsRas-association domain of sorting Nexin 27 is critical for regulating expression of GIRK potassium channelsSorting nexin 27 (SNX27) associates with zonula occludens-2 (ZO-2) and modulates the epithelial tight junctionSorting nexin 27 regulates Aβ production through modulating γ-secretase activity.Sorting nexin 17 regulates ApoER2 recycling and reelin signalingHuman papillomavirus L2 facilitates viral escape from late endosomes via sorting nexin 17.SNX17 protects integrins from degradation by sorting between lysosomal and recycling pathwaysRas trafficking, localization and compartmentalized signallingSorting nexin 27 couples PTHR trafficking to retromer for signal regulation in osteoblasts during bone growth.Actin-Sorting Nexin 27 (SNX27)-Retromer Complex Mediates Rapid Parathyroid Hormone Receptor Recycling.A defect in the retromer accessory protein, SNX27, manifests by infantile myoclonic epilepsy and neurodegeneration.Loss of sorting nexin 27 contributes to excitatory synaptic dysfunction by modulating glutamate receptor recycling in Down's syndrome.Insights into the PX (phox-homology) domain and SNX (sorting nexin) protein families: structures, functions and roles in disease.Oncogenic BRAF fusions in mucosal melanomas activate the MAPK pathway and are sensitive to MEK/PI3K inhibition or MEK/CDK4/6 inhibition.G Protein-Gated Potassium Channels: A Link to Drug Addiction.GPCR Signaling and Trafficking: The Long and Short of It.PX-FERM proteins: A link between endosomal trafficking and signaling?SNX17 regulates Notch pathway and pancreas development through the retromer-dependent recycling of Jag1.
P2860
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P2860
Phox homology band 4.1/ezrin/radixin/moesin-like proteins function as molecular scaffolds that interact with cargo receptors and Ras GTPases
description
2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Phox homology band 4.1/ezrin/r ...... argo receptors and Ras GTPases
@ast
Phox homology band 4.1/ezrin/r ...... argo receptors and Ras GTPases
@en
Phox homology band 4.1/ezrin/r ...... argo receptors and Ras GTPases
@nl
type
label
Phox homology band 4.1/ezrin/r ...... argo receptors and Ras GTPases
@ast
Phox homology band 4.1/ezrin/r ...... argo receptors and Ras GTPases
@en
Phox homology band 4.1/ezrin/r ...... argo receptors and Ras GTPases
@nl
prefLabel
Phox homology band 4.1/ezrin/r ...... argo receptors and Ras GTPases
@ast
Phox homology band 4.1/ezrin/r ...... argo receptors and Ras GTPases
@en
Phox homology band 4.1/ezrin/r ...... argo receptors and Ras GTPases
@nl
P2860
P50
P356
P1476
Phox homology band 4.1/ezrin/r ...... argo receptors and Ras GTPases
@en
P2093
Andrea Bugarcic
Suzanne J Norwood
P2860
P304
P356
10.1073/PNAS.1017110108
P407
P577
2011-05-10T00:00:00Z