Use of structure-based design to discover a potent, selective, in vivo active phosphodiesterase 10A inhibitor lead series for the treatment of schizophrenia
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Advances in targeting cyclic nucleotide phosphodiesterasesEfficient stacking on protein amide fragments.Current Understanding of PDE10A in the Modulation of Basal Ganglia Circuitry.In vitro and in vivo characterisation of Lu AF64280, a novel, brain penetrant phosphodiesterase (PDE) 2A inhibitor: potential relevance to cognitive deficits in schizophrenia.Structure-Based Design, Synthesis, Biological Evaluation, and Molecular Docking of Novel PDE10 Inhibitors With Antioxidant Activities.
P2860
Use of structure-based design to discover a potent, selective, in vivo active phosphodiesterase 10A inhibitor lead series for the treatment of schizophrenia
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Use of structure-based design ...... the treatment of schizophrenia
@ast
Use of structure-based design ...... the treatment of schizophrenia
@en
Use of structure-based design ...... the treatment of schizophrenia
@nl
type
label
Use of structure-based design ...... the treatment of schizophrenia
@ast
Use of structure-based design ...... the treatment of schizophrenia
@en
Use of structure-based design ...... the treatment of schizophrenia
@nl
prefLabel
Use of structure-based design ...... the treatment of schizophrenia
@ast
Use of structure-based design ...... the treatment of schizophrenia
@en
Use of structure-based design ...... the treatment of schizophrenia
@nl
P2093
P50
P356
P1476
Use of structure-based design ...... the treatment of schizophrenia
@en
P2093
Christopher J Helal
Christopher J Schmidt
Douglas S Chapin
Eric S Marr
Frederick R Nelson
John M Humphrey
Julia Cianfrogna
Kari R Fonseca
Kimberly F Fennell
P304
P356
10.1021/JM2001508
P407
P577
2011-06-08T00:00:00Z