Structural insights into recognition and repair of UV-DNA damage by Spore Photoproduct Lyase, a radical SAM enzyme
about
Spore photoproduct lyase: the known, the controversial, and the unknownA Radical Transfer Pathway in Spore Photoproduct LyaseThe structure of an authentic spore photoproduct lesion in DNA suggests a basis for recognitionRescuing DNA repair activity by rewiring the H-atom transfer pathway in the radical SAM enzyme, spore photoproduct lyaseCan biowarfare agents be defeated with light?Insights into the Activity Change of Spore Photoproduct Lyase Induced by Mutations at a Peripheral Glycine ResidueUnusually large deuterium discrimination during spore photoproduct formation.Glycyl radical activating enzymes: structure, mechanism, and substrate interactionsEmerging themes in radical SAM chemistryCombined Mössbauer spectroscopic, multi-edge X-ray absorption spectroscopic, and density functional theoretical study of the radical SAM enzyme spore photoproduct lyase.Recent advances in radical SAM enzymology: new structures and mechanisms.Solution phase dynamics of the DNA repair enzyme spore photoproduct lyase as probed by H/D exchange.Why Nature Uses Radical SAM Enzymes so Widely: Electron Nuclear Double Resonance Studies of Lysine 2,3-Aminomutase Show the 5'-dAdo• "Free Radical" Is Never FreePhotochemistry and Photobiology of the Spore Photoproduct: A 50-Year Journey.The thiostrepton A tryptophan methyltransferase TsrM catalyses a cob(II)alamin-dependent methyl transfer reaction.Mechanistic studies of the spore photoproduct lyase via a single cysteine mutationChemical syntheses of oligodeoxyribonucleotides containing spore photoproduct.Cysteine methylation controls radical generation in the Cfr radical AdoMet rRNA methyltransferaseThe enzyme-mediated direct reversal of a dithymine photoproduct in germinating endosporesRadical S-adenosylmethionine enzymes.Formation and Direct Repair of UV-induced Dimeric DNA Pyrimidine Lesions.Beyond xeroderma pigmentosum: DNA damage and repair in an ecological context. A tribute to James E. Cleaver.Spore photoproduct within DNA is a surprisingly poor substrate for its designated repair enzyme-The spore photoproduct lyase.Molecular architectures and functions of radical enzymes and their (re)activating proteins.Gender-related prognostic value and genomic pattern of intra-tumor heterogeneity in colorectal cancer.DNA Repair by the Radical SAM Enzyme Spore Photoproduct Lyase: From Biochemistry to Structural Investigations.Identification of natural and artificial DNA substrates for light-activated LOV-HTH transcription factor EL222Hydrogen transfer in SAM-mediated enzymatic radical reactions.Direct observation of a deoxyadenosyl radical in an active enzyme environment.Radical SAM Enzymes in the Biosynthesis of Ribosomally Synthesized and Post-translationally Modified Peptides (RiPPs).Mechanistic Investigations of PoyD, a Radical S-Adenosyl-l-methionine Enzyme Catalyzing Iterative and Directional Epimerizations in Polytheonamide A Biosynthesis.Kinetic Isotope Effects and Hydrogen/Deuterium Exchange Reveal Large Conformational Changes During the Catalysis of the Clostridium acetobutylicum Spore Photoproduct Lyase.Biochemical and Structural Characterization of a Schiff Base in the Radical-Mediated Biosynthesis of 4-Demethylwyosine by TYW1.The radical SAM enzyme spore photoproduct lyase employs a tyrosyl radical for DNA repair
P2860
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P2860
Structural insights into recognition and repair of UV-DNA damage by Spore Photoproduct Lyase, a radical SAM enzyme
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2012 nî lūn-bûn
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2012 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
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2012 թվականի հոտեմբերին հրատարակված գիտական հոդված
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2012年の論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年论文
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name
Structural insights into recog ...... ct Lyase, a radical SAM enzyme
@ast
Structural insights into recog ...... ct Lyase, a radical SAM enzyme
@en
Structural insights into recog ...... ct Lyase, a radical SAM enzyme
@nl
type
label
Structural insights into recog ...... ct Lyase, a radical SAM enzyme
@ast
Structural insights into recog ...... ct Lyase, a radical SAM enzyme
@en
Structural insights into recog ...... ct Lyase, a radical SAM enzyme
@nl
prefLabel
Structural insights into recog ...... ct Lyase, a radical SAM enzyme
@ast
Structural insights into recog ...... ct Lyase, a radical SAM enzyme
@en
Structural insights into recog ...... ct Lyase, a radical SAM enzyme
@nl
P2093
P2860
P356
P1476
Structural insights into recog ...... ct Lyase, a radical SAM enzyme
@en
P2093
Alhosna Benjdia
Korbinian Heil
Thomas R M Barends
P2860
P304
P356
10.1093/NAR/GKS603
P407
P577
2012-10-01T00:00:00Z