Lysine N -Decarboxylation Switch and Activation of the -Lactam Sensor Domain of BlaR1 Protein of Methicillin-resistant Staphylococcus aureus
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An Amino Acid Position at Crossroads of Evolution of Protein Function: ANTIBIOTIC SENSOR DOMAIN OF BlaR1 PROTEIN FROM STAPHYLOCOCCUS AUREUS VERSUS CLASS D -LACTAMASESClass D β-lactamases: a reappraisal after five decadesActivation of BlaR1 protein of methicillin-resistant Staphylococcus aureus, its proteolytic processing, and recovery from induction of resistance.Site-saturation mutagenesis of position V117 in OXA-1 β-lactamase: effect of side chain polarity on enzyme carboxylation and substrate turnover.Lysine carboxylation: unveiling a spontaneous post-translational modification.The different inhibition mechanisms of OXA-1 and OXA-24 β-lactamases are determined by the stability of active site carboxylated lysine.Bacterial cell-wall recycling.Dissection of events in the resistance to β-lactam antibiotics mediated by the protein BlaR1 from Staphylococcus aureus.Carboxylation and decarboxylation of active site Lys 84 controls the activity of OXA-24 β-lactamase of Acinetobacter baumannii: Raman crystallographic and solution evidence.13C-Carbamylation as a mechanistic probe for the inhibition of class D β-lactamases by avibactam and halide ions.A gratuitous β-Lactamase inducer uncovers hidden active site dynamics of the Staphylococcus aureus BlaR1 sensor domain.Characterization of genetic changes associated with daptomycin nonsusceptibility in Staphylococcus aureus.
P2860
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P2860
Lysine N -Decarboxylation Switch and Activation of the -Lactam Sensor Domain of BlaR1 Protein of Methicillin-resistant Staphylococcus aureus
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2011 nî lūn-bûn
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2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
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2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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Lysine N -Decarboxylation Swit ...... esistant Staphylococcus aureus
@ast
Lysine N -Decarboxylation Swit ...... esistant Staphylococcus aureus
@en
Lysine N -Decarboxylation Swit ...... esistant Staphylococcus aureus
@nl
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Lysine N -Decarboxylation Swit ...... esistant Staphylococcus aureus
@ast
Lysine N -Decarboxylation Swit ...... esistant Staphylococcus aureus
@en
Lysine N -Decarboxylation Swit ...... esistant Staphylococcus aureus
@nl
prefLabel
Lysine N -Decarboxylation Swit ...... esistant Staphylococcus aureus
@ast
Lysine N -Decarboxylation Swit ...... esistant Staphylococcus aureus
@en
Lysine N -Decarboxylation Swit ...... esistant Staphylococcus aureus
@nl
P2093
P2860
P356
P1476
Lysine N -Decarboxylation Swit ...... esistant Staphylococcus aureus
@en
P2093
Brian M Baker
Brian Wilson
Jeffrey Peng
Leticia I Llarrull
Malika Kumarasiri
Mijoon Lee
Oleg Borbulevych
P2860
P304
P356
10.1074/JBC.M111.252189
P407
P577
2011-09-09T00:00:00Z