Crystal Structure of NALP3 Protein Pyrin Domain (PYD) and Its Implications in Inflammasome Assembly - Wikidata - awgldk - TriplyDB

Crystal Structure of NALP3 Protein Pyrin Domain (PYD) and Its Implications in Inflammasome Assembly

Crystal Structure of NALP3 Protein Pyrin Domain (PYD) and Its Implications in Inflammasome Assembly

http://www.wikidata.org/entity/Q27672559

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The adaptor MAVS promotes NLRP3 mitochondrial localization and inflammasome activation Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes.Questions and controversies in innate immune research: what is the physiological role of NLRP3?Reactive oxygen species and mitochondria: A nexus of cellular homeostasis Pyrin- and CARD-only Proteins as Regulators of NLR Functions Biochemical and structural aspects of the ATP-binding domain in inflammasome-forming human NLRP proteins An Update on PYRIN Domain-Containing Pattern Recognition Receptors: From Immunity to Pathology Helical assembly in the death domain (DD) superfamily Control of innate and adaptive immunity by the inflammasome Structural and Functional Analysis of the NLRP4 Pyrin Domain Structure of the Absent in Melanoma 2 (AIM2) Pyrin Domain Provides Insights into the Mechanisms of AIM2 Autoinhibition and Inflammasome Assembly Three-Dimensional Structure of Human NLRP10/PYNOD Pyrin Domain Reveals a Homotypic Interaction Site Distinct from Its Mouse Homologue Structural Basis for the Interaction between the Potato Virus X Resistance Protein (Rx) and Its Cofactor Ran GTPase-activating Protein 2 (RanGAP2)Novel Disulfide Bond-Mediated Dimerization of the CARD Domain Was Revealed by the Crystal Structure of CARMA1 CARD Crystal Structure of the F27G AIM2 PYD Mutant and Similarities of Its Self-Association to DED/DED Interactions Structures of the NLRP14 pyrin domain reveal a conformational switch mechanism regulating its molecular interactions International Union of Basic and Clinical Pharmacology. XCVI. Pattern recognition receptors in health and disease Initiation and perpetuation of NLRP3 inflammasome activation and assembly Activation and assembly of the inflammasomes through conserved protein domain families A Novel Mutation in the Pyrin Domain of the NOD-like Receptor Family Pyrin Domain Containing Protein 3 in Muckle-Wells Syndrome.Structural features of caspase-activating complexes Identification of multifaceted binding modes for pyrin and ASC pyrin domains gives insights into pyrin inflammasome assembly.MARK4 regulates NLRP3 positioning and inflammasome activation through a microtubule-dependent mechanism Preliminary X-ray crystallographic studies of the TIR domain of human Toll-like receptor 6.PIDD mediates and stabilizes the interaction between RAIDD and caspase-2 for the PIDDosome assembly.Structural mechanisms in NLR inflammasome signaling.An updated view on the structure and function of PYRIN domains.IKKα negatively regulates ASC-dependent inflammasome activation.Crystallization and preliminary X-ray crystallographic analysis of the CARD domain of apoptosis repressor with CARD (ARC).NLRP3 inflammasome: from a danger signal sensor to a regulatory node of oxidative stress and inflammatory diseases.On the electrostatic properties of homodimeric proteins.Redox regulation of NLRP3 inflammasomes: ROS as trigger or effector?Crystal structure of caspase recruiting domain (CARD) of apoptosis repressor with CARD (ARC) and its implication in inhibition of apoptosis.Multiple binding sites on the pyrin domain of ASC protein allow self-association and interaction with NLRP3 protein.Crystallization and preliminary X-ray crystallographic studies of cPOP1 Crystallization and preliminary X-ray crystallographic studies of the CARD domain of human CARMA1 Preliminary X-ray crystallographic studies of the short form of the human TRAF4 TRAF domain.Preliminary X-ray crystallographic studies of the TRAF domain of human TRAF4 NLRP3 inflammasome and host protection against bacterial infection Crystallization and preliminary X-ray crystallographic studies of the CIDE-N domain of CIDE-3.

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Crystal Structure of NALP3 Protein Pyrin Domain (PYD) and Its Implications in Inflammasome Assembly

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2011 nî lūn-bûn

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2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2011 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2011年の論文

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Crystal Structure of NALP3 Pro ...... tions in Inflammasome Assembly

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Crystal Structure of NALP3 Pro ...... tions in Inflammasome Assembly

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Crystal Structure of NALP3 Pro ...... tions in Inflammasome Assembly

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Crystal Structure of NALP3 Pro ...... tions in Inflammasome Assembly

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Crystal Structure of NALP3 Pro ...... tions in Inflammasome Assembly

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Crystal Structure of NALP3 Pro ...... tions in Inflammasome Assembly

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Crystal Structure of NALP3 Pro ...... tions in Inflammasome Assembly

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Crystal Structure of NALP3 Pro ...... tions in Inflammasome Assembly

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Journal of Biological Chemistry

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Crystal Structure of NALP3 Pro ...... tions in Inflammasome Assembly

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Hyun Ho Park

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Ju Young Bae

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P2860

Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1

ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells

Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome

Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes

The Fas-FADD death domain complex structure reveals the basis of DISC assembly and disease mutations

The inflammasomes

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

Monomer/dimer transition of the caspase-recruitment domain of human Nod1

NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

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45

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286

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protein structure

crystal structure

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3234776

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