Engineering a model protein cavity to catalyze the Kemp elimination
about
Catalytic efficiency of designed catalytic proteinsThe Impact of Introducing a Histidine into an Apolar Cavity Site on Docking and Ligand RecognitionRoles for Ordered and Bulk Solvent in Ligand Recognition and Docking in Two Related CavitiesAlteration in the cavity size adjacent to the active site of RB69 DNA polymerase changes its conformational dynamicsRational Design, Preparation, and Characterization of a Therapeutic Enzyme Mutant with Improved Stability and Function for Cocaine DetoxificationStructural and thermodynamic consequences of burial of an artificial ion pair in the hydrophobic interior of a proteinA Promiscuous De Novo Retro-Aldolase Catalyzes Asymmetric Michael Additions via Schiff Base IntermediatesHydrogen Bonding of 1,2-Azaborines in the Binding Cavity of T4 Lysozyme Mutants: Structures and ThermodynamicsAchievements and Challenges in Computational Protein Design.RB69 DNA polymerase structure, kinetics, and fidelity.Kemp Eliminase Activity of Ketosteroid Isomerase.Improvement of biocatalysts for industrial and environmental purposes by saturation mutagenesisComputational strategies for the design of new enzymatic functionsKemp Elimination in Cationic Micelles: Designed Enzyme-Like Rates Achieved through the Addition of Long-Chain BasesRecent advances in rational approaches for enzyme engineering.A redox-mediated Kemp eliminase.De novo active sites for resurrected Precambrian enzymes.The R117A variant of the Escherichia coli transacylase FabD synthesizes novel acyl-(acyl carrier proteins).Kemp Elimination Catalyzed by Naturally Occurring Aldoxime Dehydratases.A multi-systemic mitochondrial disorder due to a dominant p.Y955H disease variant in DNA polymerase gamma.Role of conformational dynamics in the evolution of novel enzyme function.
P2860
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P2860
Engineering a model protein cavity to catalyze the Kemp elimination
description
2012 nî lūn-bûn
@nan
2012 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Engineering a model protein cavity to catalyze the Kemp elimination
@ast
Engineering a model protein cavity to catalyze the Kemp elimination
@en
Engineering a model protein cavity to catalyze the Kemp elimination
@nl
type
label
Engineering a model protein cavity to catalyze the Kemp elimination
@ast
Engineering a model protein cavity to catalyze the Kemp elimination
@en
Engineering a model protein cavity to catalyze the Kemp elimination
@nl
prefLabel
Engineering a model protein cavity to catalyze the Kemp elimination
@ast
Engineering a model protein cavity to catalyze the Kemp elimination
@en
Engineering a model protein cavity to catalyze the Kemp elimination
@nl
P2860
P356
P1476
Engineering a model protein cavity to catalyze the Kemp elimination
@en
P2093
Brian K Shoichet
P2860
P304
16179-16183
P356
10.1073/PNAS.1208076109
P407
P577
2012-09-17T00:00:00Z