Discovery of 1-amino-5H-pyrido[4,3-b]indol-4-carboxamide inhibitors of Janus kinase 2 (JAK2) for the treatment of myeloproliferative disorders

Discovery of 1-amino-5H-pyrido[4,3-b]indol-4-carboxamide inhibitors of Janus kinase 2 (JAK2) for the treatment of myeloproliferative disorders

Item
http://www.wikidata.org/entity/Q27674404
Efficacious intermittent dosing of a novel JAK2 inhibitor in mouse models of polycythemia veraEvaluation of the in vitro and in vivo efficacy of the JAK inhibitor AZD1480 against JAK-mutated acute lymphoblastic leukemia.Asymmetric synthesis of trifluoromethylated amines via catalytic enantioselective isomerization of imines.Three dimensional quantitative structure-activity relationship of 5H-Pyrido[4,3-b]indol-4-carboxamide JAK2 inhibitors.PDK1 inhibitorsSelective JAK inhibitors.Stereoselective metal-free catalytic synthesis of chiral trifluoromethyl aryl and alkyl amines.Structural insights of JAK2 inhibitors: pharmacophore modeling and ligand-based 3D-QSAR studies of pyrido-indole derivatives.A simple and facile synthesis of tricyclic-fused pyrimido[4,5-b]indol-2-amines.Dual inhibitors of Janus kinase 2 and 3 (JAK2/3): designing by pharmacophore- and docking-based virtual screening approach.Trifluoromethylation of Secondary Nitroalkanes.One-pot synthesis of carbazoles via tandem C-C cross-coupling and reductive amination.Pharmacophore and docking-based virtual screening approach for the design of new dual inhibitors of Janus kinase 1 and Janus kinase 2.
P2860

Discovery of 1-amino-5H-pyrido[4,3-b]indol-4-carboxamide inhibitors of Janus kinase 2 (JAK2) for the treatment of myeloproliferative disorders

Item
http://www.wikidata.org/entity/Q27674404
description
2011 nî lūn-bûn
@nan
2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Discovery of 1-amino-5H-pyrido ...... f myeloproliferative disorders
@ast
Discovery of 1-amino-5H-pyrido ...... f myeloproliferative disorders
@en
Discovery of 1-amino-5H-pyrido ...... f myeloproliferative disorders
@nl
type
label
Discovery of 1-amino-5H-pyrido ...... f myeloproliferative disorders
@ast
Discovery of 1-amino-5H-pyrido ...... f myeloproliferative disorders
@en
Discovery of 1-amino-5H-pyrido ...... f myeloproliferative disorders
@nl
prefLabel
Discovery of 1-amino-5H-pyrido ...... f myeloproliferative disorders
@ast
Discovery of 1-amino-5H-pyrido ...... f myeloproliferative disorders
@en
Discovery of 1-amino-5H-pyrido ...... f myeloproliferative disorders
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P577
P698
P356
P1433
P1476
Discovery of 1-amino-5H-pyrido ...... f myeloproliferative disorders
@en
P2093
P304
P31
P356
P407
P433
P478
P577
P698