Structure and mechanism of a bacterial sodium-dependent dicarboxylate transporter
about
The role of INDY in metabolism, health and longevityStructural basis for amino acid export by DMT superfamily transporter YddGIdentification of the first sodium binding site of the phosphate cotransporter NaPi-IIa (SLC34A1)Artificial citrate operon confers mineral phosphate solubilization ability to diverse fluorescent pseudomonadsMutations in the Na(+)/citrate cotransporter NaCT (SLC13A5) in pediatric patients with epilepsy and developmental delayStructure prediction of magnetosome-associated proteins.Crystallographic phasing from weak anomalous signals.Repeat-swap homology modeling of secondary active transporters: updated protocol and prediction of elevator-type mechanismsRecessive mutations in SLC13A5 result in a loss of citrate transport and cause neonatal epilepsy, developmental delay and teeth hypoplasia.Inhibition of citrate cotransporter Slc13a5/mINDY by RNAi improves hepatic insulin sensitivity and prevents diet-induced non-alcoholic fatty liver disease in mice.Correlating charge movements with local conformational changes of a Na(+)-coupled cotransporterStructure and function of the divalent anion/Na+ symporter from Vibrio cholerae and a humanized variantRobust and accurate prediction of residue-residue interactions across protein interfaces using evolutionary information.Functional characterization of a Na+-dependent dicarboxylate transporter from Vibrio cholerae.Structural insights into the elevator-like mechanism of the sodium/citrate symporter CitS.Determinants of substrate and cation transport in the human Na+/dicarboxylate cotransporter NaDC3.Mutations in SLC13A5 cause autosomal-recessive epileptic encephalopathy with seizure onset in the first days of life.Anomalous diffraction in crystallographic phase evaluationStructural insights into the transport of small molecules across membranesThe ABCs of membrane transporters in health and disease (SLC series): introduction.The Role of INDY in Metabolic RegulationThe physiological role of drug transporters.Involvement of CitCHX and CitDIC in developmental-related and postharvest-hot-air driven citrate degradation in citrus fruitsInterrogating Genes That Mediate Chlamydia trachomatis Survival in Cell Culture Using Conditional Mutants and Recombination.Knockdown of Indy/CeNac2 extends Caenorhabditis elegans life span by inducing AMPK/aak-2Family resemblances: A common fold for some dimeric ion-coupled secondary transportersPrevention of diet-induced hepatic steatosis and hepatic insulin resistance by second generation antisense oligonucleotides targeted to the longevity gene mIndy (Slc13a5)Structure-Based Identification of Inhibitors for the SLC13 Family of Na(+)/Dicarboxylate Cotransporters.Indy mutations and Drosophila longevity.SLC26A6 and NaDC-1 transporters interact to regulate oxalate and citrate homeostasis.SLC Transporters: Structure, Function, and Drug Discovery.The bacterial dicarboxylate transporter VcINDY uses a two-domain elevator-type mechanism.Convergent evolution of the arginine deiminase pathway: the ArcD and ArcE arginine/ornithine exchangersA general method for determining secondary active transporter substrate stoichiometry.Transcriptional Control of Dual Transporters Involved in α-Ketoglutarate Utilization Reveals Their Distinct Roles in Uropathogenic Escherichia coli.Structural fold and binding sites of the human Na⁺-phosphate cotransporter NaPi-IISodium-coupled dicarboxylate and citrate transporters from the SLC13 family.Expression and Purification of Haemophilus influenzae Rhomboid Intramembrane Protease GlpG for Structural Studies.The mammalian INDY homolog is induced by CREB in a rat model of type 2 diabetes.Discovery and Characterization of Novel GPR39 Agonists Allosterically Modulated by Zinc.
P2860
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P2860
Structure and mechanism of a bacterial sodium-dependent dicarboxylate transporter
description
2012 nî lūn-bûn
@nan
2012 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Structure and mechanism of a bacterial sodium-dependent dicarboxylate transporter
@ast
Structure and mechanism of a bacterial sodium-dependent dicarboxylate transporter
@en
Structure and mechanism of a bacterial sodium-dependent dicarboxylate transporter
@nl
type
label
Structure and mechanism of a bacterial sodium-dependent dicarboxylate transporter
@ast
Structure and mechanism of a bacterial sodium-dependent dicarboxylate transporter
@en
Structure and mechanism of a bacterial sodium-dependent dicarboxylate transporter
@nl
prefLabel
Structure and mechanism of a bacterial sodium-dependent dicarboxylate transporter
@ast
Structure and mechanism of a bacterial sodium-dependent dicarboxylate transporter
@en
Structure and mechanism of a bacterial sodium-dependent dicarboxylate transporter
@nl
P2860
P50
P3181
P356
P1433
P1476
Structure and mechanism of a bacterial sodium-dependent dicarboxylate transporter
@en
P2093
Romina Mancusso
P2860
P2888
P304
P3181
P356
10.1038/NATURE11542
P407
P577
2012-10-21T00:00:00Z
P5875
P6179
1008706580