Discovery of α,β- and α,γ-diamino acid scaffolds for the inhibition of M1 family aminopeptidases
about
An integrated approach to the ligand binding specificity of Neisseria meningitidis M1 alanine aminopeptidase by fluorogenic substrate profiling, inhibitory studies and molecular modeling.Structure-guided, single-point modifications in the phosphinic dipeptide structure yield highly potent and selective inhibitors of neutral aminopeptidases.A structural insight into the P1S1 binding mode of diaminoethylphosphonic and phosphinic acids, selective inhibitors of alanine aminopeptidases.Insight into the remarkable affinity and selectivity of the aminobenzosuberone scaffold for the M1 aminopeptidases family based on structure analysis.
P2860
Discovery of α,β- and α,γ-diamino acid scaffolds for the inhibition of M1 family aminopeptidases
description
2011 nî lūn-bûn
@nan
2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Discovery of α,β- and α,γ-diam ...... n of M1 family aminopeptidases
@ast
Discovery of α,β- and α,γ-diam ...... n of M1 family aminopeptidases
@en
Discovery of α,β- and α,γ-diam ...... n of M1 family aminopeptidases
@nl
type
label
Discovery of α,β- and α,γ-diam ...... n of M1 family aminopeptidases
@ast
Discovery of α,β- and α,γ-diam ...... n of M1 family aminopeptidases
@en
Discovery of α,β- and α,γ-diam ...... n of M1 family aminopeptidases
@nl
prefLabel
Discovery of α,β- and α,γ-diam ...... n of M1 family aminopeptidases
@ast
Discovery of α,β- and α,γ-diam ...... n of M1 family aminopeptidases
@en
Discovery of α,β- and α,γ-diam ...... n of M1 family aminopeptidases
@nl
P2093
P2860
P356
P1433
P1476
Discovery of α,β- and α,γ-diam ...... n of M1 family aminopeptidases
@en
P2093
Anthony Addlagatta
Chandan Kishor
Rajesh Gumpena
Roopa Jones Ganji
P2860
P304
P356
10.1002/CMDC.201100298
P577
2011-11-04T00:00:00Z